High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia ACH Smith, AR Raimondi, CD Salthouse, MS Ignatius, JS Blackburn, ... Blood, The Journal of the American Society of Hematology 115 (16), 3296-3303, 2010 | 150 | 2010 |
Glycogen synthase kinase 3 inhibitors induce the canonical WNT/β-catenin pathway to suppress growth and self-renewal in embryonal rhabdomyosarcoma EY Chen, MT DeRan, MS Ignatius, KB Grandinetti, R Clagg, KM McCarthy, ... Proceedings of the National Academy of Sciences 111 (14), 5349-5354, 2014 | 143 | 2014 |
Optimized cell transplantation using adult rag2 mutant zebrafish Q Tang, NS Abdelfattah, JS Blackburn, JC Moore, SA Martinez, FE Moore, ... Nature methods 11 (8), 821-824, 2014 | 134 | 2014 |
In vivo imaging of tumor-propagating cells, regional tumor heterogeneity, and dynamic cell movements in embryonal rhabdomyosarcoma MS Ignatius, E Chen, NM Elpek, AZ Fuller, IM Tenente, R Clagg, S Liu, ... Cancer cell 21 (5), 680-693, 2012 | 127 | 2012 |
colgate/hdac1 Repression of foxd3 expression is required to permit mitfa-dependent melanogenesis MS Ignatius, HE Moose, HM El-Hodiri, PD Henion Developmental biology 313 (2), 568-583, 2008 | 92 | 2008 |
Imaging tumour cell heterogeneity following cell transplantation into optically clear immune-deficient zebrafish Q Tang, JC Moore, MS Ignatius, IM Tenente, MN Hayes, EG Garcia, ... Nature communications 7 (1), 10358, 2016 | 89 | 2016 |
Insights into pediatric rhabdomyosarcoma research: Challenges and goals ME Yohe, CM Heske, E Stewart, PC Adamson, N Ahmed, CR Antonescu, ... Pediatric blood & cancer 66 (10), e27869, 2019 | 71 | 2019 |
Myogenic regulatory transcription factors regulate growth in rhabdomyosarcoma IM Tenente, MN Hayes, MS Ignatius, K McCarthy, M Yohe, S Sindiri, ... Elife 6, e19214, 2017 | 68 | 2017 |
Vangl2/RhoA signaling pathway regulates stem cell self-renewal programs and growth in rhabdomyosarcoma MN Hayes, K McCarthy, A Jin, ML Oliveira, S Iyer, SP Garcia, S Sindiri, ... Cell stem cell 22 (3), 414-427. e6, 2018 | 66 | 2018 |
The NOTCH1/SNAIL1/MEF2C pathway regulates growth and self-renewal in embryonal rhabdomyosarcoma MS Ignatius, MN Hayes, R Lobbardi, EY Chen, KM McCarthy, P Sreenivas, ... Cell reports 19 (11), 2304-2318, 2017 | 65 | 2017 |
A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development X Le, EK Pugach, S Hettmer, NY Storer, J Liu, AA Wills, A DiBiase, ... Development 140 (11), 2354-2364, 2013 | 63 | 2013 |
High-throughput imaging of adult fluorescent zebrafish with an LED fluorescence macroscope JS Blackburn, S Liu, AR Raimondi, MS Ignatius, CD Salthouse, ... Nature protocols 6 (2), 229-241, 2011 | 60 | 2011 |
tp53 deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish MS Ignatius, MN Hayes, FE Moore, Q Tang, SP Garcia, PR Blackburn, ... Elife 7, e37202, 2018 | 59 | 2018 |
Distinct Functional and Temporal Requirements for Zebrafish Hdac1 during Neural Crest-Derived Craniofacial and Peripheral Neuron Development MS Ignatius, A Unal Eroglu, S Malireddy, G Gallagher, RM Nambiar, ... PloS one 8 (5), e63218, 2013 | 53 | 2013 |
Zebrafish colgate/hdac1 functions in the non-canonical Wnt pathway during axial extension and in Wnt-independent branchiomotor neuron migration RM Nambiar, MS Ignatius, PD Henion Mechanisms of development 124 (9-10), 682-698, 2007 | 49 | 2007 |
Fluorescent imaging of cancer in zebrafish MS Ignatius, DM Langenau Methods in cell biology 105, 437-459, 2011 | 39 | 2011 |
Interaction between SNAI2 and MYOD enhances oncogenesis and suppresses differentiation in Fusion Negative Rhabdomyosarcoma S Pomella, P Sreenivas, BE Gryder, L Wang, D Milewski, M Cassandri, ... Nature communications 12 (1), 192, 2021 | 37 | 2021 |
Cross-species array comparative genomic hybridization identifies novel oncogenic events in zebrafish and human embryonal rhabdomyosarcoma EY Chen, KP Dobrinski, KH Brown, R Clagg, E Edelman, MS Ignatius, ... PLoS genetics 9 (8), e1003727, 2013 | 36 | 2013 |
Zebrafish as a model for cancer self-renewal MS Ignatius, DM Langenau Zebrafish 6 (4), 377-387, 2009 | 22 | 2009 |
SNAI2-Mediated Repression of BIM Protects Rhabdomyosarcoma from Ionizing Radiation L Wang, NR Hensch, K Bondra, P Sreenivas, XR Zhao, J Chen, ... Cancer research 81 (21), 5451-5463, 2021 | 13 | 2021 |