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Bhupinder Pal
Bhupinder Pal
Laboratory Head, Olivia Newton-John Cancer Research Institute
Geverifieerd e-mailadres voor onjcri.org.au - Homepage
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Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers
E Lim, F Vaillant, D Wu, NC Forrest, B Pal, AH Hart, ML Asselin-Labat, ...
Nature medicine 15 (8), 907-913, 2009
16122009
Control of mammary stem cell function by steroid hormone signalling
ML Asselin-Labat, F Vaillant, JM Sheridan, B Pal, D Wu, ER Simpson, ...
Nature 465 (7299), 798-802, 2010
7852010
Notch signaling regulates mammary stem cell function and luminal cell-fate commitment
T Bouras, B Pal, F Vaillant, G Harburg, ML Asselin-Labat, SR Oakes, ...
Cell stem cell 3 (4), 429-441, 2008
5242008
Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways
E Lim, D Wu, B Pal, T Bouras, ML Asselin-Labat, F Vaillant, H Yagita, ...
Breast Cancer Research 12, 1-14, 2010
4702010
Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells
M Rigau, S Ostrouska, TS Fulford, DN Johnson, K Woods, Z Ruan, ...
Science 367 (6478), eaay5516, 2020
3212020
Targeting BCL-2 with the BH3 mimetic ABT-199 in estrogen receptor-positive breast cancer
F Vaillant, D Merino, L Lee, K Breslin, B Pal, ME Ritchie, GK Smyth, ...
Cancer cell 24 (1), 120-129, 2013
3042013
RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers
E Nolan, F Vaillant, D Branstetter, B Pal, G Giner, L Whitehead, SW Lok, ...
Nature medicine 22 (8), 933-939, 2016
2662016
Construction of developmental lineage relationships in the mouse mammary gland by single-cell RNA profiling
B Pal, Y Chen, F Vaillant, P Jamieson, L Gordon, AC Rios, S Wilcox, N Fu, ...
Nature communications 8 (1), 1627, 2017
1792017
A single‐cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast
B Pal, Y Chen, F Vaillant, BD Capaldo, R Joyce, X Song, VL Bryant, ...
The EMBO journal 40 (11), e107333, 2021
1722021
Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer
D Merino, JR Whittle, F Vaillant, A Serrano, JN Gong, G Giner, ...
Science translational medicine 9 (401), eaam7049, 2017
1712017
Global changes in the mammary epigenome are induced by hormonal cues and coordinated by Ezh2
B Pal, T Bouras, W Shi, F Vaillant, JM Sheridan, N Fu, K Breslin, K Jiang, ...
Cell reports 3 (2), 411-426, 2013
1492013
Intraclonal plasticity in mammary tumors revealed through large-scale single-cell resolution 3D imaging
AC Rios, BD Capaldo, F Vaillant, B Pal, R van Ineveld, CA Dawson, ...
Cancer cell 35 (4), 618-632. e6, 2019
1432019
Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling
CA Dawson, B Pal, F Vaillant, LC Gandolfo, Z Liu, C Bleriot, F Ginhoux, ...
Nature cell biology 22 (5), 546-558, 2020
1262020
A phase Ib dose-escalation and expansion study of the BCL2 inhibitor venetoclax combined with tamoxifen in ER and BCL2–positive metastatic breast cancer
SW Lok, JR Whittle, F Vaillant, CE Teh, LL Lo, AN Policheni, ART Bergin, ...
Cancer discovery 9 (3), 354-369, 2019
1252019
Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer
D Merino, TS Weber, A Serrano, F Vaillant, K Liu, B Pal, L Di Stefano, ...
Nature communications 10 (1), 766, 2019
1222019
Identification of quiescent and spatially restricted mammary stem cells that are hormone responsive
NY Fu, AC Rios, B Pal, CW Law, P Jamieson, R Liu, F Vaillant, F Jackling, ...
Nature cell biology 19 (3), 164-176, 2017
1142017
EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival
NY Fu, AC Rios, B Pal, R Soetanto, ATL Lun, K Liu, T Beck, SA Best, ...
Nature Cell Biology 17 (4), 365-375, 2015
892015
Taurine deficiency as a driver of aging
P Singh, K Gollapalli, S Mangiola, D Schranner, MA Yusuf, M Chamoli, ...
Science 380 (6649), eabn9257, 2023
882023
Essential role for a novel population of binucleated mammary epithelial cells in lactation
AC Rios, NY Fu, PR Jamieson, B Pal, L Whitehead, KR Nicholas, ...
Nature communications 7 (1), 11400, 2016
882016
Differential methylation analysis of reduced representation bisulfite sequencing experiments using edgeR
Y Chen, B Pal, JE Visvader, GK Smyth
F1000Research 6, 2017
852017
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