Juan Carlos Acosta Cobacho
Juan Carlos Acosta Cobacho
Institute of Biomedicine and Biotechnology of Cantabria, Universidad de Cantabria, CSIC
Verified email at - Homepage
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Chemokine signaling via the CXCR2 receptor reinforces senescence
JC Acosta, A O'Loghlen, A Banito, MV Guijarro, A Augert, S Raguz, ...
cell 133 (6), 1006-1018, 2008
A complex secretory program orchestrated by the inflammasome controls paracrine senescence
JC Acosta, A Banito, T Wuestefeld, A Georgilis, P Janich, JP Morton, ...
Nature cell biology 15 (8), 978-990, 2013
Senescence impairs successful reprogramming to pluripotent stem cells
A Banito, ST Rashid, JC Acosta, SD Li, CF Pereira, I Geti, S Pinho, ...
Genes & development 23 (18), 2134-2139, 2009
mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype
N Herranz, S Gallage, M Mellone, T Wuestefeld, S Klotz, CJ Hanley, ...
Nature cell biology 17 (9), 1205-1217, 2015
Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS
M Barradas, E Anderton, JC Acosta, SD Li, A Banito, ...
Genes & development 23 (10), 1177-1182, 2009
Senescence: a new weapon for cancer therapy
JC Acosta, J Gil
Trends in cell biology 22 (4), 211-219, 2012
p21Cip1 and p27Kip1 induce distinct cell cycle effects and differentiation programs in myeloid leukemia cells
MJ Muñoz-Alonso, JC Acosta, C Richard, MD Delgado, J Sedivy, J León
Journal of Biological Chemistry 280 (18), 18120-18129, 2005
Paracrine cellular senescence exacerbates biliary injury and impairs regeneration
S Ferreira-Gonzalez, WY Lu, A Raven, B Dwyer, TY Man, E O’Duibhir, ...
Nature communications 9 (1), 1020, 2018
SKP2 oncogene is a direct MYC target gene and MYC down-regulates p27KIP1 through SKP2 in human leukemia cells
G Bretones, JC Acosta, JM Caraballo, N Ferrándiz, MT Gómez-Casares, ...
Journal of Biological Chemistry 286 (11), 9815-9825, 2011
Control of senescence by CXCR2 and its ligands
JC Acosta, A Loghlen, A Banito, S Raguz, J Gil
Cell cycle 7 (19), 2956-2959, 2008
A role for CXCR2 in senescence, but what about in cancer?
JC Acosta, J Gil
Cancer research 69 (6), 2167-2170, 2009
The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype
P Hari, FR Millar, N Tarrats, J Birch, A Quintanilla, CJ Rink, ...
Science advances 5 (6), eaaw0254, 2019
Suppression of autophagy impedes glioblastoma development and induces senescence
N Gammoh, J Fraser, C Puente, HM Syred, H Kang, T Ozawa, D Lam, ...
Autophagy 12 (9), 1431-1439, 2016
Inhibition of cell differentiation: a critical mechanism for MYC-mediated carcinogenesis?
J Leon, N Ferrandiz, JC Acosta, MD Delgado
Cell Cycle 8 (8), 1148-1157, 2009
An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition
HL Young, EJ Rowling, M Bugatti, E Giurisato, N Luheshi, I Arozarena, ...
Journal of Experimental Medicine 214 (6), 1691-1710, 2017
Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest
JC Acosta, N Ferrándiz, G Bretones, V Torrano, R Blanco, C Richard, ...
Molecular and cellular biology 28 (24), 7286-7295, 2008
Notch signaling mediates secondary senescence
YV Teo, N Rattanavirotkul, N Olova, A Salzano, A Quintanilla, N Tarrats, ...
Cell Reports 27 (4), 997-1007. e5, 2019
MYC in chronic myeloid leukemia: induction of aberrant DNA synthesis and association with poor response to imatinib
M Albajar, MT Gómez-Casares, J Llorca, I Mauleon, JP Vaqué, JC Acosta, ...
Molecular Cancer Research 9 (5), 564-576, 2011
Nuclear pore density controls heterochromatin reorganization during senescence
C Boumendil, P Hari, KCF Olsen, JC Acosta, WA Bickmore
Genes & development 33 (3-4), 144-149, 2019
PHD3 regulates p53 protein stability by hydroxylating proline 359
J Rodriguez, A Herrero, S Li, N Rauch, A Quintanilla, K Wynne, A Krstic, ...
Cell reports 24 (5), 1316-1329, 2018
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