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Denis A Malyshev
Denis A Malyshev
Scientist, Omniome INC
Geverifieerd e-mailadres voor synthorx.com - Homepage
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A semi-synthetic organism with an expanded genetic alphabet
DA Malyshev, K Dhami, T Lavergne, T Chen, N Dai, JM Foster, IR Corrêa, ...
Nature 509 (7500), 385-388, 2014
6602014
The expanded genetic alphabet
DA Malyshev, FE Romesberg
Angewandte Chemie International Edition 54 (41), 11930-11944, 2015
2092015
Vicinal amino alcohols as organocatalysts in asymmetric cross-aldol reaction of ketones: application in the synthesis of convolutamydine A
AV Malkov, MA Kabeshov, M Bella, O Kysilka, DA Malyshev, ...
Organic Letters 9 (26), 5473-5476, 2007
2062007
Homogeneous nickel catalysts for the selective transfer of a single arylthio group in the catalytic hydrothiolation of alkynes
DA Malyshev, NM Scott, N Marion, ED Stevens, VP Ananikov, ...
Organometallics 25 (19), 4462-4470, 2006
1882006
Efficient and sequence-independent replication of DNA containing a third base pair establishes a functional six-letter genetic alphabet
DA Malyshev, K Dhami, HT Quach, T Lavergne, P Ordoukhanian, ...
Proceedings of the National Academy of Sciences 109 (30), 12005-12010, 2012
1752012
Natural-like replication of an unnatural base pair for the expansion of the genetic alphabet and biotechnology applications
L Li, M Degardin, T Lavergne, DA Malyshev, K Dhami, P Ordoukhanian, ...
Journal of the American Chemical Society 136 (3), 826-829, 2014
1732014
PCR with an expanded genetic alphabet
DA Malyshev, YJ Seo, P Ordoukhanian, FE Romesberg
Journal of the American Chemical Society 131 (41), 14620-14621, 2009
1612009
KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry
K Betz, DA Malyshev, T Lavergne, W Welte, K Diederichs, TJ Dwyer, ...
Nature chemical biology 8 (7), 612-614, 2012
1532012
Nickel (II) Chloride‐Catalyzed Regioselective Hydrothiolation of Alkynes
VP Ananikov, DA Malyshev, IP Beletskaya, GG Aleksandrov, IL Eremenko
Advanced Synthesis & Catalysis 347 (15), 1993-2001, 2005
1202005
Site-specific labeling of DNA and RNA using an efficiently replicated and transcribed class of unnatural base pairs
YJ Seo, DA Malyshev, T Lavergne, P Ordoukhanian, FE Romesberg
Journal of the American Chemical Society 133 (49), 19878-19888, 2011
1102011
Solution structure, mechanism of replication, and optimization of an unnatural base pair
DA Malyshev, DA Pfaff, SI Ippoliti, GT Hwang, TJ Dwyer, FE Romesberg
Chemistry–A European Journal 16 (42), 12650-12659, 2010
902010
Structural insights into DNA replication without hydrogen bonds
K Betz, DA Malyshev, T Lavergne, W Welte, K Diederichs, FE Romesberg, ...
Journal of the American Chemical Society 135 (49), 18637-18643, 2013
862013
Systematic exploration of a class of hydrophobic unnatural base pairs yields multiple new candidates for the expansion of the genetic alphabet
K Dhami, DA Malyshev, P Ordoukhanian, T Kubelka, M Hocek, ...
Nucleic acids research 42 (16), 10235-10244, 2014
822014
Palladium and platinum catalyzed hydroselenation of alkynes: Se H vs Se Se addition to C C bond
VP Ananikov, DA Malyshev, IP Beletskaya, GG Aleksandrov, IL Eremenko
Journal of organometallic chemistry 679 (2), 162-172, 2003
792003
A personalized platform identifies trametinib plus zoledronate for a patient with KRAS-mutant metastatic colorectal cancer
E Bangi, C Ang, P Smibert, AV Uzilov, AG Teague, Y Antipin, R Chen, ...
Science Advances 5 (5), eaav6528, 2019
752019
Vanadium-catalyzed asymmetric epoxidation of allylic alcohols in water
AV Malkov, L Czemerys, DA Malyshev
The Journal of Organic Chemistry 74 (9), 3350-3355, 2009
622009
Sila Morita− Baylis− Hillman Reaction of Cyclopropenes
S Chuprakov, DA Malyshev, A Trofimov, V Gevorgyan
Journal of the American Chemical Society 129 (48), 14868-14869, 2007
572007
Major groove substituents and polymerase recognition of a class of predominantly hydrophobic unnatural base pairs
T Lavergne, DA Malyshev, FE Romesberg
Chemistry–A European Journal 18 (4), 1231-1239, 2012
542012
Expanding the scope of replicable unnatural DNA: stepwise optimization of a predominantly hydrophobic base pair
T Lavergne, M Degardin, DA Malyshev, HT Quach, K Dhami, ...
Journal of the American Chemical Society 135 (14), 5408-5419, 2013
492013
FRET characterization of complex conformational changes in a large 16S ribosomal RNA fragment site-specifically labeled using unnatural base pairs
T Lavergne, R Lamichhane, DA Malyshev, Z Li, L Li, E Sperling, ...
ACS chemical biology 11 (5), 1347-1353, 2016
472016
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Artikelen 1–20