| Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux RE Lee, JG Hurdle, J Liu, DF Bruhn, T Matt, MS Scherman, PK Vaddady, ... Nature medicine 20 (2), 152-158, 2014 | 184 | 2014 |
| Binding affinity prediction with property-encoded shape distribution signatures S Das, MP Krein, CM Breneman Journal of chemical information and modeling 50 (2), 298-308, 2010 | 76 | 2010 |
| Rapid comparison of protein binding site surfaces with property encoded shape distributions S Das, A Kokardekar, CM Breneman Journal of chemical information and modeling 49 (12), 2863-2872, 2009 | 63 | 2009 |
| Phenyl‐Glutarimides: Alternative Cereblon Binders for the Design of PROTACs J Min, A Mayasundari, F Keramatnia, B Jonchere, SW Yang, J Jarusiewicz, ... Angewandte Chemie International Edition 60 (51), 26663-26670, 2021 | 57 | 2021 |
| Identification of potent, selective, and orally bioavailable small-molecule GSPT1/2 degraders from a focused library of cereblon modulators G Nishiguchi, F Keramatnia, J Min, Y Chang, B Jonchere, S Das, M Actis, ... Journal of medicinal chemistry 64 (11), 7296-7311, 2021 | 57 | 2021 |
| Current trends in virtual high throughput screening using ligand-based and structure-based methods N Sukumar, S Das Combinatorial chemistry & high throughput screening 14 (10), 872-888, 2011 | 49 | 2011 |
| Targeting histone demethylases in MYC-driven neuroblastomas with ciclopirox J Yang, S Milasta, D Hu, AM AlTahan, RB Interiano, J Zhou, J Davidson, ... Cancer research 77 (17), 4626-4638, 2017 | 47 | 2017 |
| Structure–activity relationships of spectinamide antituberculosis agents: a dissection of ribosomal inhibition and native efflux avoidance contributions J Liu, DF Bruhn, RB Lee, Z Zheng, T Janusic, D Scherbakov, ... ACS infectious diseases 3 (1), 72-88, 2017 | 38 | 2017 |
| ABCG2 requires a single aromatic amino acid to “clamp” substrates and inhibitors into the binding pocket T Gose, T Shafi, Y Fukuda, S Das, Y Wang, A Allcock, AG McHarg, ... FASEB journal: official publication of the Federation of American Societies …, 2020 | 31 | 2020 |
| Bromodomain-selective BET inhibitors are potent antitumor agents against MYC-driven pediatric cancer PJ Slavish, L Chi, MK Yun, L Tsurkan, NE Martinez, B Jonchere, SC Chai, ... Cancer research 80 (17), 3507-3518, 2020 | 30 | 2020 |
| PESDserv: a server for high-throughput comparison of protein binding site surfaces S Das, MP Krein, CM Breneman Bioinformatics 26 (15), 1913-1914, 2010 | 18 | 2010 |
| Novel vitexin-inspired scaffold against leukemia T Ling, W Lang, X Feng, S Das, J Maier, C Jeffries, A Shelat, F Rivas European Journal of Medicinal Chemistry 146, 501-510, 2018 | 17 | 2018 |
| Synthesis of bi-substrate state mimics of dihydropteroate synthase as potential inhibitors and molecular probes J Qi, KG Virga, S Das, Y Zhao, MK Yun, SW White, RE Lee Bioorganic & medicinal chemistry 19 (3), 1298-1305, 2011 | 16 | 2011 |
| Small molecule sequestration of the intrinsically disordered protein, p27Kip1, within soluble oligomers LI Iconaru, S Das, A Nourse, AA Shelat, J Zuo, RW Kriwacki Journal of molecular biology 433 (18), 167120, 2021 | 15 | 2021 |
| Mechanisms of Resistance Associated with the Inhibition of the Dehydration Step of Type II Fatty Acid Synthase in Mycobacterium tuberculosis AE Grzegorzewicz, C Gee, S Das, J Liu, JM Belardinelli, V Jones, ... ACS infectious diseases 6 (2), 195-204, 2019 | 11 | 2019 |
| Development of a pterin-based fluorescent probe for screening dihydropteroate synthase Y Zhao, D Hammoudeh, W Lin, S Das, MK Yun, Z Li, E Griffith, T Chen, ... Bioconjugate Chemistry 22 (10), 2110-2117, 2011 | 11 | 2011 |
| Composition for reduction of trpa1 and trpv1 sensations JC Haught, K Sreekrishna, S Das, IISH HOKE, TW Coffindaffer, KA Bakes, ... US Patent App. 13/873,749, 2013 | 10 | 2013 |
| Synthesis and evaluation of colletoic acid core derivatives T Ling, LN Gautam, E Griffith, S Das, W Lang, WR Shadrick, A Shelat, ... European Journal of Medicinal Chemistry 110, 126-132, 2016 | 9 | 2016 |
| Evaluating and evolving a screening library in academia: the St Jude approach G Nishiguchi, S Das, J Ochoada, H Long, RE Lee, Z Rankovic, AA Shelat Drug discovery today 26 (4), 1060-1069, 2021 | 8 | 2021 |
| 17-DMAG dually inhibits Hsp90 and histone lysine demethylases in alveolar rhabdomyosarcoma S Singh, A Abu-Zaid, W Lin, J Low, A Abdolvahabi, H Jin, Q Wu, B Cooke, ... Iscience 24 (1), 2021 | 8 | 2021 |
