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Paul K. Ziegler
Paul K. Ziegler
Principal Investigator at Dr. Senckenberg Institute of Pathology Frankfurt University Hospital
Verified email at paul-ziegler.com
Title
Cited by
Cited by
Year
Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties
S Schwitalla, AA Fingerle, P Cammareri, T Nebelsiek, SI Göktuna, ...
Cell 152 (1), 25-38, 2013
11452013
IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis
M Rokavec, MG Öner, H Li, R Jackstadt, L Jiang, D Lodygin, M Kaller, ...
The Journal of clinical investigation 124 (4), 1853-1867, 2014
7732014
IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis
M Rokavec, MG Öner, H Li, R Jackstadt, L Jiang, D Lodygin, M Kaller, ...
The Journal of clinical investigation 124 (4), 1853-1867, 2014
7732014
High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity
MD Schulz, Ç Atay, J Heringer, FK Romrig, S Schwitalla, B Aydin, ...
Nature 514 (7523), 508-512, 2014
4682014
Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically
TL Putoczki, S Thiem, A Loving, RA Busuttil, NJ Wilson, PK Ziegler, ...
Cancer cell 24 (2), 257-271, 2013
4222013
Loss of p53 in enterocytes generates an inflammatory microenvironment enabling invasion and lymph node metastasis of carcinogen-induced colorectal tumors
S Schwitalla, PK Ziegler, D Horst, V Becker, I Kerle, Y Begus-Nahrmann, ...
Cancer cell 23 (1), 93-106, 2013
2982013
IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis
CK Pallangyo, PK Ziegler, FR Greten
Journal of experimental medicine 212 (13), 2253-2266, 2015
1412015
Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer
AM Nicolas, M Pesic, E Engel, PK Ziegler, M Diefenhardt, KB Kennel, ...
Cancer Cell 40 (2), 168-184. e13, 2022
1392022
Mitophagy in intestinal epithelial cells triggers adaptive immunity during tumorigenesis
PK Ziegler, J Bollrath, CK Pallangyo, T Matsutani, Ö Canli, T De Oliveira, ...
Cell 174 (1), 88-101. e16, 2018
1112018
AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer
J Varga, A Nicolas, V Petrocelli, M Pesic, A Mahmoud, BE Michels, ...
Journal of Experimental Medicine 217 (10), e20191515, 2020
612020
Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy
D Denk, V Petrocelli, C Conche, M Drachsler, PK Ziegler, A Braun, ...
Immunity 55 (11), 2059-2073. e8, 2022
402022
TNF-α–dependent loss of IKKβ-deficient myeloid progenitors triggers a cytokine loop culminating in granulocytosis
AK Mankan, O Canli, S Schwitalla, P Ziegler, J Tschopp, T Korn, ...
Proceedings of the National Academy of Sciences 108 (16), 6567-6572, 2011
352011
Complete pathological response after neoadjuvant short-course immunotherapy with ipilimumab and nivolumab in locally advanced MSI-H/dMMR rectal cancer
J Trojan, S Stintzing, O Haase, C Koch, P Ziegler, M Demes, I Jelas
The oncologist 26 (12), e2110-e2114, 2021
302021
Loss of Stat6 affects chromatin condensation in intestinal epithelial cells causing diverse outcome in murine models of inflammation-associated and sporadic colon carcinogenesis
T De Oliveira, M Ramakrishnan, MA Diamanti, PK Ziegler, F Brombacher, ...
Oncogene 38 (11), 1787-1801, 2019
142019
Colorectal cancer organoid–stroma biobank allows subtype-specific assessment of individualized therapy responses
HF Farin, MH Mosa, B Ndreshkjana, BM Grebbin, B Ritter, C Menche, ...
Cancer discovery 13 (10), 2192-2211, 2023
132023
Evaluation of prognostic factors after primary chemoradiotherapy of anal cancer: A multicenter study of the German Cancer Consortium-Radiation Oncology Group (DKTK-ROG)
D Martin, T Schreckenbach, P Ziegler, N Filmann, G Kalinauskaite, ...
Radiotherapy and Oncology 167, 233-238, 2022
72022
How to learn with intentional mistakes: Noisyensembles to overcome poor tissue quality for deep learning in computational pathology
RS Mayer, S Gretser, LE Heckmann, PK Ziegler, B Walter, H Reis, ...
Frontiers in Medicine 9, 959068, 2022
52022
Transglutaminase 2 is associated with adverse colorectal cancer survival and represents a therapeutic target
P Malkomes, I Lunger, E Oppermann, J Lorenz, SF Faqar-Uz-Zaman, ...
Cancer Gene Therapy 30 (10), 1346-1354, 2023
42023
Multi-magnification networks for deformable image registration on histopathology images
O Cetin, Y Shu, N Flinner, P Ziegler, P Wild, H Koeppl
International Workshop on Biomedical Image Registration, 124-133, 2022
42022
Fluorescence confocal microscopy on liver specimens for full digitization of transplant pathology
MN Kinzler, F Schulze, A Reitz, S Gretser, P Ziegler, O Shmorhun, ...
Liver Transplantation 29 (9), 940-951, 2023
32023
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