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Bruce Sachais
Bruce Sachais
Chief Medical Officer, New York Blood Center
Geverifieerd e-mailadres voor nybc.org
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Deployment of convalescent plasma for the prevention and treatment of COVID-19
EM Bloch, S Shoham, A Casadevall, BS Sachais, B Shaz, JL Winters, ...
The Journal of clinical investigation 130 (6), 2757-2765, 2020
9382020
Evidence‐based practice guidelines for plasma transfusion
JD Roback, S Caldwell, J Carson, R Davenport, MJ Drew, A Eder, M Fung, ...
Transfusion 50 (6), 1227-1239, 2010
3682010
Ultralarge complexes of PF4 and heparin are central to the pathogenesis of heparin-induced thrombocytopenia
L Rauova, M Poncz, SE McKenzie, MP Reilly, G Arepally, JW Weisel, ...
Blood 105 (1), 131-138, 2005
3202005
Heparin-induced thrombocytopenia/thrombosis in a transgenic mouse model requires human platelet factor 4 and platelet activation through FcγRIIA
MP Reilly, SM Taylor, NK Hartman, GM Arepally, BS Sachais, DB Cines, ...
Blood, The Journal of the American Society of Hematology 98 (8), 2442-2447, 2001
2812001
Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial
P Bégin, J Callum, E Jamula, R Cook, NM Heddle, A Tinmouth, MP Zeller, ...
Nature medicine 27 (11), 2012-2024, 2021
2402021
Platelet factor 4 localization in carotid atherosclerotic plaques: correlation with clinical parameters
S Pitsilos, J Hunt, ER Mohler, AM Prabhakar, M Poncz, J Dawicki, ...
Thrombosis and haemostasis 90 (12), 1112-1120, 2003
2322003
Efficacy of transfusion with granulocytes from G-CSF/dexamethasone–treated donors in neutropenic patients with infection
TH Price, M Boeckh, RW Harrison, J McCullough, PM Ness, RG Strauss, ...
Blood, The Journal of the American Society of Hematology 126 (18), 2153-2161, 2015
2242015
Molecular cloning, structural characterization and functional expression of the human substance P receptor
Y Takeda, KB Chou, J Takeda, BS Sachais, JE Krause
Biochemical and biophysical research communications 179 (3), 1232-1240, 1991
2191991
Factor VIII ectopically expressed in platelets: efficacy in hemophilia A treatment
HV Yarovoi, D Kufrin, DE Eslin, MA Thornton, SL Haberichter, Q Shi, ...
Blood 102 (12), 4006-4013, 2003
2142003
Platelet factor 4 enhances the binding of oxidized low-density lipoprotein to vascular wall cells
T Nassar, BS Sachais, S Akkawi, MA Kowalska, K Bdeir, E Leitersdorf, ...
Journal of Biological Chemistry 278 (8), 6187-6193, 2003
1962003
Elimination of platelet factor 4 (PF4) from platelets reduces atherosclerosis in C57Bl/6 and apoE-/-mice
BS Sachais, T Turrentine, JMD McKenna, AH Rux, D Rader, ...
Thrombosis and haemostasis 98 (11), 1108-1113, 2007
1782007
A peptide derived from the nonreceptor binding region of urokinase plasminogen activator (uPA) inhibits tumor progression and angiogenesis and induces tumor cell death in vivo
Y Guo, AAR Higazi, A Arakelian, BS Sachais, D Cines, RH Goldfarb, ...
The FASEB Journal 14 (10), 1400-1410, 2000
1572000
Endothelial expression of E-selectin is induced by the platelet-specific chemokine platelet factor 4 through LRP in an NF-κB–dependent manner
G Yu, AH Rux, P Ma, K Bdeir, BS Sachais
Blood 105 (9), 3545-3551, 2005
1542005
Molecular basis for the species selectivity of the substance P antagonist CP-96,345.
BS Sachais, RM Snider, JA Lowe 3rd, JE Krause
Journal of Biological Chemistry 268 (4), 2319-2323, 1993
1521993
The cooperative activity between the carboxyl-terminal TSP1 repeats and the CUB domains of ADAMTS13 is crucial for recognition of von Willebrand factor under flow
P Zhang, W Pan, AH Rux, BS Sachais, XL Zheng
Blood, The Journal of the American Society of Hematology 110 (6), 1887-1894, 2007
1482007
Platelets regulate CD4+ T-cell differentiation via multiple chemokines in humans
N Gerdes, L Zhu, M Ersoy, A Hermansson, P Hjemdahl, H Hu, ...
Thrombosis and haemostasis 106 (08), 353-362, 2011
1422011
Platelet factor 4 binds to low-density lipoprotein receptors and disrupts the endocytic itinerary, resulting in retention of low-density lipoprotein on the cell surface
BS Sachais, A Kuo, T Nassar, J Morgan, K Kariko, KJ Williams, ...
Blood, The Journal of the American Society of Hematology 99 (10), 3613-3622, 2002
1272002
Ligand binding kinetics of substance P and neurokinin A receptors stably expressed in Chinese hamster ovary cells and evidence for differential stimulation of inositol 1, 4, 5 …
Y Takeda, P Blount, BS Sachais, AD Hershey, R Raddatz, JE Krause
Journal of neurochemistry 59 (2), 740-745, 1992
1181992
Heparin‐induced thrombocytopenia: an autoimmune disorder regulated through dynamic autoantigen assembly/disassembly
DB Cines, L Rauova, G Arepally, MP Reilly, SE McKenzie, BS Sachais, ...
Journal of Clinical Apheresis: The Official Journal of the American Society …, 2007
1012007
Defensin promotes the binding of lipoprotein (a) to vascular matrix
K Bdeir, W Cane, G Canziani, I Chaiken, J Weisel, ML Koschinsky, ...
Blood, The Journal of the American Society of Hematology 94 (6), 2007-2019, 1999
951999
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Artikelen 1–20