Antonio Covacci
Antonio Covacci
Novartis Vaccines
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cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors
S Censini, C Lange, Z Xiang, JE Crabtree, P Ghiara, M Borodovsky, ...
Proceedings of the National Academy of Sciences 93 (25), 14648-14653, 1996
Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer.
A Covacci, S Censini, M Bugnoli, R Petracca, D Burroni, G Macchia, ...
Proceedings of the National Academy of Sciences 90 (12), 5791-5795, 1993
Helicobacter pylori Adhesin Binding Fucosylated Histo-Blood Group Antigens Revealed by Retagging
D Ilver, A Arnqvist, J Ogren, IM Frick, D Kersulyte, ET Incecik, DE Berg, ...
Science 279 (5349), 373-377, 1998
Helicobacter pylori Virulence and Genetic Geography
A Covacci, JL Telford, GD Giudice, J Parsonnet, R Rappuoli
Science 284 (5418), 1328-1333, 1999
Disruption of the Epithelial Apical-Junctional Complex by Helicobacter pylori CagA
MR Amieva, R Vogelmann, A Covacci, LS Tompkins, WJ Nelson, ...
Science 300 (5624), 1430-1434, 2003
Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA …
Z Xiang, S Censini, PF Bayeli, JL Telford, N Figura, R Rappuoli, ...
Infection and immunity 63 (1), 94-98, 1995
Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag-driven host cell translocation
M Stein, R Rappuoli, A Covacci
Proceedings of the National Academy of Sciences 97 (3), 1263-1268, 2000
Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease.
JL Telford, P Ghiara, M Dell'Orco, M Comanducci, D Burroni, M Bugnoli, ...
The Journal of experimental medicine 179 (5), 1653-1658, 1994
Coxsackie B4 virus infection of β cells and natural killer cell insulitis in recent-onset type 1 diabetic patients
F Dotta, S Censini, AGS van Halteren, L Marselli, M Masini, S Dionisi, ...
Proceedings of the National Academy of Sciences 104 (12), 5115-5120, 2007
A pneumococcal pilus influences virulence and host inflammatory responses
MA Barocchi, J Ries, X Zogaj, C Hemsley, B Albiger, A Kanth, S Dahlberg, ...
Proceedings of the National Academy of Sciences 103 (8), 2857-2862, 2006
c‐Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs
M Stein, F Bagnoli, R Halenbeck, R Rappuoli, WJ Fantl, A Covacci
Molecular microbiology 43 (4), 971-980, 2002
Helicobacter pylori induced interleukin-8 expression in gastric epithelial cells is associated with CagA positive phenotype.
JE Crabtree, A Covacci, SM Farmery, Z Xiang, DS Tompkins, S Perry, ...
Journal of clinical pathology 48 (1), 41-45, 1995
Mutants of pertussis toxin suitable for vaccine development
M Pizza, A Covacci, A Bartoloni, M Perugini, L Nencioni, MT De Magistris, ...
Science 246 (4929), 497-500, 1989
Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species
C Donati, NL Hiller, H Tettelin, A Muzzi, NJ Croucher, SV Angiuoli, ...
Genome biology 11 (10), 1-19, 2010
Helicobacter pylori activates mitogen-activated protein kinase cascades and induces expression of the proto-oncogenes c-fos and c-jun
T Meyer-ter-Vehn, A Covacci, M Kist, HL Pahl
Journal of Biological Chemistry 275 (21), 16064-16072, 2000
The Design of Vaccines Against Helicobacter Pylori and Their Development
G Del Giudice, A Covacci, JL Telford, C Montecucco, R Rappuoli
Annual review of immunology 19 (1), 523-563, 2001
Helicobacter pylori CagA induces a transition from polarized to invasive phenotypes in MDCK cells
F Bagnoli, L Buti, L Tompkins, A Covacci, MR Amieva
Proceedings of the National Academy of Sciences 102 (45), 16339-16344, 2005
Induction of host signal transduction pathways by Helicobacter pylori
ED Segal, C Lange, A Covacci, LS Tompkins, S Falkow
Proceedings of the National Academy of Sciences 94 (14), 7595-7599, 1997
The Complete Genome Sequence of Helicobacter pylori Strain G27
DA Baltrus, MR Amieva, A Covacci, TM Lowe, DS Merrell, KM Ottemann, ...
Journal of bacteriology 191 (1), 447-448, 2009
The Complete Genome Sequence of Fibrobacter succinogenes S85 Reveals a Cellulolytic and Metabolic Specialist
G Suen, PJ Weimer, DM Stevenson, FO Aylward, J Boyum, J Deneke, ...
PloS one 6 (4), e18814, 2011
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