Christopher Dobson
Christopher Dobson
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Protein misfolding, functional amyloid, and human disease
F Chiti, CM Dobson
Annu. Rev. Biochem. 75, 333-366, 2006
58432006
Protein folding and misfolding
CM Dobson
Nature 426 (6968), 884-890, 2003
45402003
Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases
M Bucciantini, E Giannoni, F Chiti, F Baroni, L Formigli, J Zurdo, N Taddei, ...
nature 416 (6880), 507-511, 2002
25742002
Protein misfolding, evolution and disease
CM Dobson
Trends in biochemical sciences 24 (9), 329-332, 1999
21391999
Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution
M Stefani, CM Dobson
Journal of molecular medicine 81 (11), 678-699, 2003
17012003
The amyloid state and its association with protein misfolding diseases
TPJ Knowles, M Vendruscolo, CM Dobson
Nature reviews Molecular cell biology 15 (6), 384-396, 2014
13582014
Designing conditions for in vitro formation of amyloid protofilaments and fibrils
F Chiti, P Webster, N Taddei, A Clark, M Stefani, G Ramponi, CM Dobson
Proceedings of the National Academy of Sciences 96 (7), 3590-3594, 1999
12181999
Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis
DR Booth, M Sunde, V Bellotti, CV Robinson, WL Hutchinson, PE Fraser, ...
Nature 385 (6619), 787-793, 1997
11671997
Rationalization of the effects of mutations on peptide andprotein aggregation rates
F Chiti, M Stefani, N Taddei, G Ramponi, CM Dobson
Nature 424 (6950), 805-808, 2003
11132003
The structural basis of protein folding and its links with human disease
CM Dobson
Philosophical Transactions of the Royal Society of London. Series B …, 2001
10112001
Principles of protein folding, misfolding and aggregation
CM Dobson
Seminars in cell & developmental biology 15 (1), 3-16, 2004
9972004
Protein folding: a perspective from theory and experiment
CM Dobson, A Šali, M Karplus
Angewandte Chemie International Edition 37 (7), 868-893, 1998
9691998
Chemical space and biology
CM Dobson
Nature 432 (7019), 824, 2004
8962004
Hydrodynamic radii of native and denatured proteins measured by pulse field gradient NMR techniques
DK Wilkins, SB Grimshaw, V Receveur, CM Dobson, JA Jones, LJ Smith
Biochemistry 38 (50), 16424-16431, 1999
8831999
The protofilament structure of insulin amyloid fibrils
JL Jimenez, EJ Nettleton, M Bouchard, CV Robinson, CM Dobson, ...
Proceedings of the National Academy of Sciences 99 (14), 9196-9201, 2002
8702002
Amyloid fibrils from muscle myoglobin
M Fändrich, MA Fletcher, CM Dobson
Nature 410 (6825), 165-166, 2001
8672001
The folding of hen lysozyme involves partially structured intermediates and multiple pathways
SE Radford, CM Dobson, PA Evans
Nature 358 (6384), 302-307, 1992
8201992
An analytical solution to the kinetics of breakable filament assembly
TPJ Knowles, CA Waudby, GL Devlin, SIA Cohen, A Aguzzi, ...
Science 326 (5959), 1533-1537, 2009
8142009
Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism
SIA Cohen, S Linse, LM Luheshi, E Hellstrand, DA White, L Rajah, ...
Proceedings of the National Academy of Sciences 110 (24), 9758-9763, 2013
7662013
Amyloid formation by globular proteins under native conditions
F Chiti, CM Dobson
Nature chemical biology 5 (1), 15, 2009
7642009
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Artikelen 1–20