| Identification of proteins directly from tissue: in situ tryptic digestions coupled with imaging mass spectrometry MR Groseclose, M Andersson, WM Hardesty, RM Caprioli Journal of Mass Spectrometry 42 (2), 254-262, 2007 | 431 | 2007 |
| High‐throughput proteomic analysis of formalin‐fixed paraffin‐embedded tissue microarrays using MALDI imaging mass spectrometry MR Groseclose, PP Massion, P Chaurand, RM Caprioli Proteomics 8 (18), 3715-3724, 2008 | 374 | 2008 |
| Imaging mass spectrometry of proteins and peptides: 3D volume reconstruction M Andersson, MR Groseclose, AY Deutch, RM Caprioli Nature methods 5 (1), 101-108, 2008 | 296 | 2008 |
| Advanced MALDI mass spectrometry imaging in pharmaceutical research and drug development S Schulz, M Becker, MR Groseclose, S Schadt, C Hopf Current opinion in biotechnology 55, 51-59, 2019 | 275 | 2019 |
| MALDI imaging mass spectrometry: bridging biology and chemistry in drug development S Castellino, MR Groseclose, D Wagner Bioanalysis 3 (21), 2427-2441, 2011 | 255 | 2011 |
| A mimetic tissue model for the quantification of drug distributions by MALDI imaging mass spectrometry MR Groseclose, S Castellino Analytical chemistry 85 (21), 10099-10106, 2013 | 221 | 2013 |
| HER2-overexpressing breast cancers amplify FGFR signaling upon acquisition of resistance to dual therapeutic blockade of HER2 AB Hanker, JT Garrett, MV Estrada, PD Moore, PG Ericsson, JP Koch, ... Clinical Cancer Research 23 (15), 4323-4334, 2017 | 81 | 2017 |
| Central nervous system disposition and metabolism of fosdevirine (GSK2248761), a non-nucleoside reverse transcriptase inhibitor: an LC-MS and matrix-assisted laser desorption … S Castellino, MR Groseclose, J Sigafoos, D Wagner, M de Serres, ... Chemical research in toxicology 26 (2), 241-251, 2013 | 81 | 2013 |
| Assessing drug and metabolite detection in liver tissue by UV-MALDI and IR-MALDESI mass spectrometry imaging coupled to FT-ICR MS JA Barry, MR Groseclose, G Robichaud, S Castellino, DC Muddiman International journal of mass spectrometry 377, 448-455, 2015 | 58 | 2015 |
| Imaging MS in toxicology: an investigation of juvenile rat nephrotoxicity associated with dabrafenib administration MR Groseclose, SB Laffan, KS Frazier, A Hughes-Earle, S Castellino Journal of the american society for mass spectrometry 26 (6), 887-898, 2015 | 55 | 2015 |
| Quantification and assessment of detection capability in imaging mass spectrometry using a revised mimetic tissue model JA Barry, MR Groseclose, S Castellino Bioanalysis 11 (11), 1099-1116, 2019 | 51 | 2019 |
| An investigation into retigabine (ezogabine) associated dyspigmentation in rat eyes by MALDI imaging mass spectrometry MR Groseclose, S Castellino Chemical Research in Toxicology 32 (2), 294-303, 2019 | 47 | 2019 |
| Multimodal imaging approach to examine biodistribution kinetics of Cabotegravir (GSK1265744) long acting parenteral formulation in rat BM Jucker, H Alsaid, M Rambo, SC Lenhard, B Hoang, F Xie, ... Journal of Controlled Release 268, 102-112, 2017 | 32 | 2017 |
| Spatially aware clustering of ion images in mass spectrometry imaging data using deep learning W Zhang, M Claesen, T Moerman, MR Groseclose, E Waelkens, ... Analytical and bioanalytical chemistry 413, 2803-2819, 2021 | 31 | 2021 |
| Intramuscular and subcutaneous drug depot characterization of a long-acting cabotegravir nanoformulation by MALDI IMS MR Groseclose, S Castellino International Journal of Mass Spectrometry 437, 92-98, 2019 | 24 | 2019 |
| Drug-induced liver fibrosis: testing nevirapine in a viral-like liver setting using histopathology, MALDI IMS, and gene expression HR Brown, S Castellino, MR Groseclose, CS Elangbam, ... Toxicologic pathology 44 (1), 112-131, 2016 | 24 | 2016 |
| Imaging mass spectrometry analysis for follicular lymphoma grading SS Samsi, AK Krishnamurthy, MR Groseclose, RM Caprioli, G Lozanski, ... 2009 Annual International Conference of the IEEE Engineering in Medicine and …, 2009 | 23 | 2009 |
| From proteomic multimarker profiling to interesting proteins: thymosin‐β4 and kininogen‐1 as new potential biomarkers for inflammatory hepatic lesions C Henkel, K Schwamborn, HW Zimmermann, F Tacke, E Kühnen, ... Journal of Cellular and Molecular Medicine 15 (10), 2176-2188, 2011 | 22 | 2011 |
| The emergence of imaging mass spectrometry in drug discovery and development: Making a difference by driving decision making S Castellino, NM Lareau, MR Groseclose Journal of Mass Spectrometry 56 (8), e4717, 2021 | 19 | 2021 |
| Revised preparation of a mimetic tissue model for quantitative imaging mass spectrometry JA Barry, MR Groseclose, DD Fraser, S Castellino | 19 | 2018 |
William HardestyGlaxoSmithKlineVerified email at gsk.com
William HardestyGlaxoSmithKlineVerified email at gsk.com