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Jian XU
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Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A
VG Sankaran, TF Menne, J Xu, TE Akie, G Lettre, B Van Handel, ...
Science 322 (5909), 1839-1842, 2008
10202008
An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level
DE Bauer, SC Kamran, S Lessard, J Xu, Y Fujiwara, C Lin, Z Shao, ...
Science 342 (6155), 253-257, 2013
6562013
Developmental and species-divergent globin switching are driven by BCL11A
VG Sankaran, J Xu, T Ragoczy, GC Ippolito, CR Walkley, SD Maika, ...
Nature 460 (7259), 1093-1097, 2009
4712009
Transcriptional silencing of γ-globin by BCL11A involves long-range interactions and cooperation with SOX6
J Xu, VG Sankaran, M Ni, TF Menne, RV Puram, W Kim, SH Orkin
Genes & development 24 (8), 783-798, 2010
4562010
Direct promoter repression by BCL11A controls the fetal to adult hemoglobin switch
N Liu, VV Hargreaves, Q Zhu, JV Kurland, J Hong, W Kim, F Sher, ...
Cell 173 (2), 430-442. e17, 2018
3842018
Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing
J Xu, C Peng, VG Sankaran, Z Shao, EB Esrick, BG Chong, GC Ippolito, ...
Science 334 (6058), 993-996, 2011
3642011
Polycomb repressive complex 2 regulates normal hematopoietic stem cell function in a developmental-stage-specific manner
H Xie, J Xu, JH Hsu, M Nguyen, Y Fujiwara, C Peng, SH Orkin
Cell stem cell 14 (1), 68-80, 2014
3242014
Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin
T Masuda, X Wang, M Maeda, MC Canver, F Sher, APW Funnell, C Fisher, ...
Science 351 (6270), 285-289, 2016
3222016
In situ capture of chromatin interactions by biotinylated dCas9
X Liu, Y Zhang, Y Chen, M Li, F Zhou, K Li, H Cao, M Ni, Y Liu, Z Gu, ...
Cell 170 (5), 1028-1043. e19, 2017
2792017
Mapping cellular hierarchy by single-cell analysis of the cell surface repertoire
G Guo, S Luc, E Marco, TW Lin, C Peng, MA Kerenyi, S Beyaz, W Kim, ...
Cell stem cell 13 (4), 492-505, 2013
2742013
The mitochondrial respiratory chain is essential for haematopoietic stem cell function
E Ansó, SE Weinberg, LP Diebold, BJ Thompson, S Malinge, ...
Nature cell biology 19 (6), 614-625, 2017
2652017
CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells
J Kim, Z Hu, L Cai, K Li, E Choi, B Faubert, D Bezwada, ...
Nature 546 (7656), 168-172, 2017
2632017
Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production
Y Li, V Esain, L Teng, J Xu, W Kwan, IM Frost, AD Yzaguirre, X Cai, ...
Genes & development 28 (23), 2597-2612, 2014
2602014
Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A
J Xu, DE Bauer, MA Kerenyi, TD Vo, S Hou, YJ Hsu, H Yao, JJ Trowbridge, ...
Proceedings of the National Academy of Sciences 110 (16), 6518-6523, 2013
2572013
Methylation profiling of twenty promoter-CpG islands of genes which may contribute to hepatocellular carcinogenesis
J Yu, M Ni, J Xu, H Zhang, B Gao, J Gu, J Chen, L Zhang, M Wu, S Zhen, ...
BMC cancer 2, 1-14, 2002
2572002
Advances in the understanding of haemoglobin switching
VG Sankaran, J Xu, SH Orkin
British journal of haematology 149 (2), 181-194, 2010
2522010
Dynamic control of enhancer repertoires drives lineage and stage-specific transcription during hematopoiesis
J Huang, X Liu, D Li, Z Shao, H Cao, Y Zhang, E Trompouki, TV Bowman, ...
Developmental cell 36 (1), 9-23, 2016
2232016
Combinatorial assembly of developmental stage-specific enhancers controls gene expression programs during human erythropoiesis
J Xu, Z Shao, K Glass, DE Bauer, L Pinello, B Van Handel, S Hou, ...
Developmental cell 23 (4), 796-811, 2012
2232012
Dissecting super-enhancer hierarchy based on chromatin interactions
J Huang, K Li, W Cai, X Liu, Y Zhang, SH Orkin, J Xu, GC Yuan
Nature communications 9 (1), 943, 2018
2082018
Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells
J Xu, JA Watts, SD Pope, P Gadue, M Kamps, K Plath, KS Zaret, ST Smale
Genes & development 23 (24), 2824-2838, 2009
2022009
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