Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease B Zhang, C Gaiteri, LG Bodea, Z Wang, J McElwee, AA Podtelezhnikov, ... Cell 153 (3), 707-720, 2013 | 1819 | 2013 |
A molecular network of the aging human brain provides insights into the pathology and cognitive decline of Alzheimer’s disease S Mostafavi, C Gaiteri, SE Sullivan, CC White, S Tasaki, J Xu, M Taga, ... Nature neuroscience 21 (6), 811-819, 2018 | 447 | 2018 |
A multi-omic atlas of the human frontal cortex for aging and Alzheimer’s disease research PL De Jager, Y Ma, C McCabe, J Xu, BN Vardarajan, D Felsky, HU Klein, ... Scientific data 5 (1), 1-13, 2018 | 431 | 2018 |
An xQTL map integrates the genetic architecture of the human brain's transcriptome and epigenome B Ng, CC White, HU Klein, SK Sieberts, C McCabe, E Patrick, J Xu, L Yu, ... Nature neuroscience 20 (10), 1418-1426, 2017 | 429 | 2017 |
Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level ECB Johnson, EK Carter, EB Dammer, DM Duong, ES Gerasimov, Y Liu, ... Nature Neuroscience, 1-13, 2022 | 355 | 2022 |
Beyond modules and hubs: the potential of gene coexpression networks for investigating molecular mechanisms of complex brain disorders C Gaiteri, Y Ding, B French, GC Tseng, E Sibille Genes, Brain and Behavior 13 (1), 13-24, 2014 | 281 | 2014 |
Meta-analysis of the Alzheimer’s disease human brain transcriptome and functional dissection in mouse models YW Wan, R Al-Ouran, CG Mangleburg, TM Perumal, TV Lee, K Allison, ... Cell reports 32 (2), 107908, 2020 | 243 | 2020 |
A molecular signature of depression in the amygdala E Sibille, Y Wang, J Joeyen-Waldorf, C Gaiteri, A Surget, S Oh, C Belzung, ... American journal of psychiatry 166 (9), 1011-1024, 2009 | 229 | 2009 |
Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease M Giraldo, F Lopera, AL Siniard, JJ Corneveaux, I Schrauwen, J Carvajal, ... Neurobiology of aging 34 (8), 2077. e11-2077. e18, 2013 | 173 | 2013 |
Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia L Yu, VA Petyuk, C Gaiteri, S Mostafavi, T Young‐Pearse, RC Shah, ... Annals of neurology, 2018 | 111 | 2018 |
Genetic variants in Alzheimer disease—molecular and brain network approaches C Gaiteri, S Mostafavi, CJ Honey, PL De Jager, DA Bennett Nature Reviews Neurology 12 (7), 413, 2016 | 108 | 2016 |
Deconvolving the contributions of cell-type heterogeneity on cortical gene expression E Patrick, M Taga, A Ergun, B Ng, W Casazza, M Cimpean, C Yung, ... PLOS Computational Biology 16 (8), e1008120, 2020 | 104 | 2020 |
Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors VN Lagomarsino, RV Pearse II, L Liu, YC Hsieh, MA Fernandez, ... Neuron 109 (21), 3402-3420. e9, 2021 | 100 | 2021 |
Identifying robust communities and multi-community nodes by combining top-down and bottom-up approaches to clustering C Gaiteri, M Chen, B Szymanski, K Kuzmin, J Xie, C Lee, T Blanche, ... Scientific reports 5 (1), 1-14, 2015 | 83 | 2015 |
Seasonal plasticity of cognition and related biological measures in adults with and without Alzheimer disease: Analysis of multiple cohorts ASP Lim, C Gaiteri, L Yu, S Sohail, W Swardfager, S Tasaki, JA Schneider, ... PLoS medicine 15 (9), e1002647, 2018 | 69 | 2018 |
TOMM40′ 523 variant and cognitive decline in older persons with APOE ε3/3 genotype L Yu, MW Lutz, RS Wilson, DK Burns, AD Roses, AM Saunders, C Gaiteri, ... Neurology 88 (7), 661-668, 2017 | 60 | 2017 |
Altered gene synchrony suggests a combined hormone-mediated dysregulated state in major depression C Gaiteri, JP Guilloux, DA Lewis, E Sibille PloS one 5 (4), e9970, 2010 | 58 | 2010 |
The molecular and neuropathological consequences of genetic risk for Alzheimer’s dementia S Tasaki, C Gaiteri, S Mostafavi, P De Jager, DA Bennett Frontiers in Neuroscience 12, 699, 2018 | 55 | 2018 |
Benchmarking of deep neural networks for predicting personal gene expression from DNA sequence highlights shortcomings A Sasse, B Ng, AE Spiro, S Tasaki, DA Bennett, C Gaiteri, PL De Jager, ... Nature Genetics, 1-5, 2023 | 51 | 2023 |
Inferring protein expression changes from mRNA in Alzheimer’s dementia using deep neural networks S Tasaki, J Xu, DR Avey, L Johnson, VA Petyuk, RJ Dawe, DA Bennett, ... Nature Communications 13 (1), 1-15, 2022 | 51 | 2022 |