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Aimee M. Deaton
Aimee M. Deaton
Director, Alnylam Pharmaceuticals
Verified email at alnylam.com
Title
Cited by
Cited by
Year
CpG islands and the regulation of transcription
AM Deaton, A Bird
Genes & development 25 (10), 1010-1022, 2011
36922011
CpG islands influence chromatin structure via the CpG-binding protein Cfp1
JP Thomson, PJ Skene, J Selfridge, T Clouaire, J Guy, S Webb, ARW Kerr, ...
Nature 464 (7291), 1082-1086, 2010
7602010
A transient heterochromatic state in Xist preempts X inactivation choice without RNA stabilization
BK Sun, AM Deaton, JT Lee
Molecular cell 21 (5), 617-628, 2006
3722006
Cell type–specific DNA methylation at intragenic CpG islands in the immune system
AM Deaton, S Webb, ARW Kerr, RS Illingworth, J Guy, R Andrews, A Bird
Genome research 21 (7), 1074-1086, 2011
3482011
MNase titration reveals differences between nucleosome occupancy and chromatin accessibility
J Mieczkowski, A Cook, SK Bowman, B Mueller, BH Alver, S Kundu, ...
Nature communications 7 (1), 11485, 2016
2392016
A temporal threshold for formaldehyde crosslinking and fixation
L Schmiedeberg, P Skene, A Deaton, A Bird
PLoS One 4 (2), e4636, 2009
1412009
H3K27 modifications define segmental regulatory domains in the Drosophila bithorax complex
SK Bowman, AM Deaton, H Domingues, PI Wang, RI Sadreyev, ...
Elife 3, e02833, 2014
1282014
A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis
RP Kristjansson, S Benonisdottir, OB Davidsson, A Oddsson, V Tragante, ...
Nature genetics 51 (2), 267-276, 2019
1022019
Nucleosomal occupancy changes locally over key regulatory regions during cell differentiation and reprogramming
JA West, A Cook, BH Alver, M Stadtfeld, AM Deaton, K Hochedlinger, ...
Nature communications 5 (1), 4719, 2014
1022014
Enhancer regions show high histone H3. 3 turnover that changes during differentiation
AM Deaton, M Gomez-Rodriguez, J Mieczkowski, MY Tolstorukov, ...
elife 5, e15316, 2016
972016
Genome-wide association meta-analysis yields 20 loci associated with gallstone disease
E Ferkingstad, A Oddsson, S Gretarsdottir, S Benonisdottir, G Thorleifsson, ...
Nature communications 9 (1), 5101, 2018
882018
Multiplexed Illumina sequencing libraries from picogram quantities of DNA
SK Bowman, MD Simon, AM Deaton, M Tolstorukov, ML Borowsky, ...
BMC genomics 14, 1-7, 2013
882013
A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells
PC Cook, H Owen, AM Deaton, JG Borger, SL Brown, T Clouaire, ...
Nature communications 6 (1), 6920, 2015
842015
Plasma proteomic associations with genetics and health in the UK Biobank
BB Sun, J Chiou, M Traylor, C Benner, YH Hsu, TG Richardson, ...
Nature 622 (7982), 329-338, 2023
832023
Phenotypes associated with genes encoding drug targets are predictive of clinical trial side effects
PA Nguyen, DA Born, AM Deaton, P Nioi, LD Ward
Nature communications 10 (1), 1579, 2019
832019
Nonclinical cardiovascular safety evaluation of romosozumab, an inhibitor of sclerostin for the treatment of osteoporosis in postmenopausal women at high risk of fracture
JR Turk, AM Deaton, J Yin, M Stolina, M Felx, G Boyd, JG Bienvenu, ...
Regulatory Toxicology and Pharmacology 115, 104697, 2020
352020
Specificity of Atonal and Scute bHLH factors: analysis of cognate E box binding sites and the influence of Senseless
LM Powell, AM Deaton, MA Wear, AP Jarman
Genes to Cells 13 (9), 915-929, 2008
342008
Gene-level analysis of rare variants in 379,066 whole exome sequences identifies an association of GIGYF1 loss of function with type 2 diabetes
AM Deaton, MM Parker, LD Ward, AO Flynn-Carroll, L BonDurant, ...
Scientific reports 11 (1), 21565, 2021
322021
A unique DNA methylation signature defines a population of IFN‐γ/IL‐4 double‐positive T cells during helminth infection
AM Deaton, PC Cook, D De Sousa, AT Phythian‐Adams, A Bird, ...
European journal of immunology 44 (6), 1835-1841, 2014
302014
GWAS of serum ALT and AST reveals an association of SLC30A10 Thr95Ile with hypermanganesemia symptoms
LD Ward, HC Tu, CB Quenneville, S Tsour, AO Flynn-Carroll, MM Parker, ...
Nature Communications 12 (1), 4571, 2021
29*2021
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