Simon Dujardin, PhD
Simon Dujardin, PhD
Post-doctoral fellow, Massachusetts General Hospital, Harvard Medical School
Geverifieerd e-mailadres voor mgh.harvard.edu - Homepage
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Tau protein liquid–liquid phase separation can initiate tau aggregation
S Wegmann, B Eftekharzadeh, K Tepper, KM Zoltowska, RE Bennett, ...
The EMBO journal 37 (7), e98049, 2018
1632018
Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies
S Dujardin, K Lécolle, R Caillierez, S Bégard, N Zommer, C Lachaud, ...
Acta neuropathologica communications 2 (1), 14, 2014
1512014
CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia
H Makishima, AM Jankowska, MA McDevitt, C O'Keefe, S Dujardin, ...
Blood 117 (21), e198-e206, 2011
1432011
Ectosomes: a new mechanism for non-exosomal secretion of tau protein
S Dujardin, S Bégard, R Caillierez, C Lachaud, L Delattre, S Carrier, ...
PloS one 9 (6), e100760, 2014
1082014
What is the evidence that tau pathology spreads through prion-like propagation?
A Mudher, M Colin, S Dujardin, M Medina, I Dewachter, SMA Naini, ...
Acta neuropathologica communications 5 (1), 99, 2017
992017
Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies
M Tardivel, S Bégard, L Bousset, S Dujardin, A Coens, R Melki, L Buée, ...
Acta neuropathologica communications 4 (1), 117, 2016
942016
Tau protein disrupts nucleocytoplasmic transport in Alzheimer’s disease
B Eftekharzadeh, JG Daigle, LE Kapinos, A Coyne, J Schiantarelli, ...
Neuron 99 (5), 925-940. e7, 2018
822018
Tau impairs neural circuits, dominating amyloid-β effects, in Alzheimer models in vivo
MA Busche, S Wegmann, S Dujardin, C Commins, J Schiantarelli, ...
Nature neuroscience 22 (1), 57-64, 2019
702019
Enhanced tau aggregation in the presence of amyloid β
RE Bennett, SL DeVos, S Dujardin, B Corjuc, R Gor, J Gonzalez, AD Roe, ...
The American journal of pathology 187 (7), 1601-1612, 2017
632017
Invited review: animal models of tauopathies and their implications for research/translation into the clinic
S Dujardin, M Colin, L Buée
Neuropathology and applied neurobiology 41 (1), 59-80, 2015
402015
Lentiviral delivery of the human wild-type tau protein mediates a slow and progressive neurodegenerative tau pathology in the rat brain
R Caillierez, S Bégard, K Lécolle, V Deramecourt, N Zommer, S Dujardin, ...
Molecular Therapy 21 (7), 1358-1368, 2013
312013
Clinical, neuropathological, and biochemical characterization of the novel tau mutation P332S
V Deramecourt, F Lebert, CA Maurage, FJ Fernandez-Gomez, S Dujardin, ...
Journal of Alzheimer's Disease 31 (4), 741-749, 2012
302012
Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo
SL DeVos, BT Corjuc, C Commins, S Dujardin, RN Bannon, D Corjuc, ...
Brain 141 (7), 2194-2212, 2018
252018
Different tau species lead to heterogeneous tau pathology propagation and misfolding
S Dujardin, S Bégard, R Caillierez, C Lachaud, S Carrier, S Lieger, ...
Acta neuropathologica communications 6 (1), 1-12, 2018
242018
From the prion-like propagation hypothesis to therapeutic strategies of anti-tau immunotherapy
M Colin, S Dujardin, S Schraen-Maschke, G Meno-Tetang, C Duyckaerts, ...
Acta neuropathologica, 1-23, 2020
172020
Correction: Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer’s Disease
B Eftekharzadeh, JG Daigle, LE Kapinos, A Coyne, J Schiantarelli, ...
Neuron 101 (2), 349, 2019
52019
In vivo detection of tau fibrils and amyloid β aggregates with luminescent conjugated oligothiophenes and multiphoton microscopy
M Calvo-Rodriguez, SS Hou, AC Snyder, S Dujardin, H Shirani, ...
Acta neuropathologica communications 7 (1), 1-10, 2019
32019
Tau prion-like propagation: state of the art and current challenges
S Dujardin, BT Hyman
Tau Biology, 305-325, 2019
22019
Selection of an efficient AAV vector for robust CNS transgene expression
KS Hanlon, JC Meltzer, T Buzhdygan, MJ Cheng, M Sena-Esteves, ...
Molecular Therapy-Methods & Clinical Development 15, 320-332, 2019
12019
European Society of Gene and Cell Therapy French Society of Cell and Gene Therapy Collaborative Congress 2012 October 25–29, 2012 Palais des Congrès de Versailles Versailles …
T VandenDriessche, RA Pearson, RJ Chandler, CC Bartholomae, ...
Human Gene Therapy 23 (10), A1-A173, 2012
12012
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