Gonadotropin-releasing hormone receptors RP Millar, ZL Lu, AJ Pawson, CA Flanagan, K Morgan, SR Maudsley Endocrine reviews 25 (2), 235-275, 2004 | 921 | 2004 |
Cloning and functional expression of a mouse gonadotropin-releasing hormone receptor. M Tsutsumi, W Zhou, RP Millar, PL Mellon, JL Roberts, CA Flanagan, ... Molecular Endocrinology 6 (7), 1163-1169, 1992 | 464 | 1992 |
A reciprocal mutation supports helix 2 and helix 7 proximity in the gonadotropin-releasing hormone receptor. W Zhou, C Flanagan, JA Ballesteros, K Konvicka, JS Davidson, ... Molecular pharmacology 45 (2), 165-170, 1994 | 327 | 1994 |
Cloning and characterization of the human GnRH receptor L Chi, W Zhou, A Prikhozhan, C Flanagan, JS Davidson, M Golembo, ... Molecular and cellular endocrinology 91 (1-2), R1-R6, 1993 | 269 | 1993 |
Gonadotropin-releasing hormone (GnRH)-binding sites in human breast cancer cell lines and inhibitory effects of GnRH antagonists KA Eidne, CA Flanagan, NS Harris, RP Millar The Journal of Clinical Endocrinology & Metabolism 64 (3), 425-432, 1987 | 269 | 1987 |
Gonadotropin-releasing hormone binding sites in human breast carcinoma KA Eidne, CA Flanagan, RP Millar Science 229 (4717), 989-991, 1985 | 234 | 1985 |
Glutamate 301 of the mouse gonadotropin-releasing hormone receptor confers specificity for arginine 8 of mammalian gonadotropin-releasing hormone. CA Flanagan, II Becker, JS Davidson, IK Wakefield, W Zhou, SC Sealfon, ... Journal of Biological Chemistry 269 (36), 22636-22641, 1994 | 155 | 1994 |
A Locus of the Gonadotropin-releasing Hormone Receptor That Differentiates Agonist and Antagonist Binding Sites (∗) W Zhou, V Rodic, S Kitanovic, CA Flanagan, L Chi, H Weinstein, ... Journal of Biological Chemistry 270 (32), 18853-18857, 1995 | 128 | 1995 |
Asn102 of the gonadotropin-releasing hormone receptor is a critical determinant of potency for agonists containing C-terminal glycinamide JS Davidson, CA McArdle, P Davies, R Elario, CA Flanagan, RP Millar Journal of Biological Chemistry 271 (26), 15510-15514, 1996 | 112 | 1996 |
Identification of N-glycosylation sites in the gonadotropin-releasing hormone receptor: role in receptor expression but not ligand binding JS Davidson, CA Flanagan, W Zhou, II Becker, R Elario, W Emeran, ... Molecular and cellular endocrinology 107 (2), 241-245, 1995 | 104 | 1995 |
Chimeric Analogues of Vertebrate Gonadotropin-Releasing Hormones Comprising Substitutions of the Variant Amino Acids in Positions 5, 7, and 8: Characterization of requirements … RP Millar, CA Flanagan, RC Milton, JA King Journal of Biological Chemistry 264 (35), 21007-21013, 1989 | 100 | 1989 |
Comparative sequence analysis and functional characterization of the cloned sheep gonadotropin-releasing hormone receptor reveals differences in primary structure and ligand … N Illing, GFM Jacobs, II Becker, CA Flanagan, JS Davidson, A Eales, ... Biochemical and biophysical research communications 196 (2), 745-751, 1993 | 99 | 1993 |
The functional microdomain in transmembrane helices 2 and 7 regulates expression, activation, and coupling pathways of the gonadotropin-releasing hormone receptor CA Flanagan, W Zhou, L Chi, T Yuen, V Rodic, D Robertson, M Johnson, ... Journal of Biological Chemistry 274 (41), 28880-28886, 1999 | 93 | 1999 |
A GPCR that is not “DRY” CA Flanagan Molecular pharmacology 68 (1), 1-3, 2005 | 88 | 2005 |
A chicken gonadotropin-releasing hormone receptor that confers agonist activity to mammalian antagonists: identification of D-Lys6 in the ligand and extracellular loop two of … YM Sun, CA Flanagan, N Illing, TR Ott, R Sellar, BJ Fromme, J Hapgood, ... Journal of Biological Chemistry 276 (11), 7754-7761, 2001 | 88 | 2001 |
Multiple interactions of the Asp2. 61 (98) side chain of the gonadotropin-releasing hormone receptor contribute differentially to ligand interaction CA Flanagan, V Rodic, K Konvicka, T Yuen, L Chi, JE Rivier, RP Millar, ... Biochemistry 39 (28), 8133-8141, 2000 | 85 | 2000 |
Role of aspartate7. 32 (302) of the human gonadotropin-releasing hormone receptor in stabilizing a high-affinity ligand conformation BJ Fromme, AA Katz, RW Roeske, RP Millar, CA Flanagan Molecular pharmacology 60 (6), 1280-1287, 2001 | 77 | 2001 |
Irreversible activation of the gonadotropin-releasing hormone receptor by photoaffinity cross-linking: localization of attachment site to Cys residue in N-terminal segment JS Davidson, D Assefa, Pawson, J Hapgood, Becker, Flanagan, ... Biochemistry 36 (42), 12881-12889, 1997 | 73 | 1997 |
Gonadotropin-releasing hormone (GnRH) receptor structure and GnRH binding CA Flanagan, A Manilall Frontiers in endocrinology 8, 301334, 2017 | 71 | 2017 |
Advances in understanding gonadotrophin-releasing hormone receptor structure and ligand interactions CA Flanagan, RP Millar, N Illing Reviews of reproduction 2, 113-120, 1997 | 65 | 1997 |