Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex LM Machesky, RD Mullins, HN Higgs, DA Kaiser, L Blanchoin, RC May, ... Proceedings of the National Academy of Sciences 96 (7), 3739-3744, 1999 | 1006 | 1999 |
The many faces of actin: matching assembly factors with cellular structures ES Chhabra, HN Higgs Nature cell biology 9 (10), 1110-1121, 2007 | 956 | 2007 |
Regulation of actin filament network formation through ARP2/3 complex: activation by a diverse array of proteins HN Higgs, TD Pollard Annual review of biochemistry 70 (1), 649-676, 2001 | 895 | 2001 |
An actin-dependent step in mitochondrial fission mediated by the ER-associated formin INF2 F Korobova, V Ramabhadran, HN Higgs Science 339 (6118), 464-467, 2013 | 796 | 2013 |
Crystal structure of Arp2/3 complex RC Robinson, K Turbedsky, DA Kaiser, JB Marchand, HN Higgs, S Choe, ... science 294 (5547), 1679-1684, 2001 | 745 | 2001 |
Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins L Blanchoin, KJ Amann, HN Higgs, JB Marchand, DA Kaiser, TD Pollard Nature 404 (6781), 1007-1011, 2000 | 734 | 2000 |
The human androgen receptor: complementary deoxyribonucleic acid cloning, sequence analysis and gene expression in prostate DB Lubahn, DR Joseph, M Sar, J Tan, HN Higgs, RE Larson, FS French, ... Molecular endocrinology 2 (12), 1265-1275, 1988 | 697 | 1988 |
Control of the assembly of ATP-and ADP-actin by formins and profilin DR Kovar, ES Harris, R Mahaffy, HN Higgs, TD Pollard Cell 124 (2), 423-435, 2006 | 691 | 2006 |
Activation by Cdc42 and Pip2 of Wiskott-Aldrich Syndrome Protein (Wasp) Stimulates Actin Nucleation by Arp2/3 Complex HN Higgs, TD Pollard The Journal of cell biology 150 (6), 1311-1320, 2000 | 684 | 2000 |
Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutation in a family with complete androgen … DB Lubahn, TR Brown, JA Simental, HN Higgs, CJ Migeon, EM Wilson, ... Proceedings of the National Academy of Sciences 86 (23), 9534-9538, 1989 | 568 | 1989 |
The mouse Formin mDia1 is a potent actin nucleation factor regulated by autoinhibition F Li, HN Higgs Current biology 13 (15), 1335-1340, 2003 | 545 | 2003 |
Formin proteins: a domain-based approach HN Higgs Trends in biochemical sciences 30 (6), 342-353, 2005 | 523 | 2005 |
Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis EJ Brown, JS Schlöndorff, DJ Becker, H Tsukaguchi, SJ Tonna, ... Nature genetics 42 (1), 72-76, 2010 | 513 | 2010 |
Ena/VASP proteins enhance actin polymerization in the presence of barbed end capping proteins M Barzik, TI Kotova, HN Higgs, L Hazelwood, D Hanein, FB Gertler, ... Journal of Biological Chemistry 280 (31), 28653-28662, 2005 | 438 | 2005 |
Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 complex JB Marchand, DA Kaiser, TD Pollard, HN Higgs Nature cell biology 3 (1), 76-82, 2001 | 429 | 2001 |
Phylogenetic analysis of the formin homology 2 domain HN Higgs, KJ Peterson Molecular biology of the cell 16 (1), 1-13, 2005 | 353 | 2005 |
Regulation of actin polymerization by Arp2/3 complex and WASp/Scar proteins HN Higgs, TD Pollard Journal of Biological Chemistry 274 (46), 32531-32534, 1999 | 351 | 1999 |
Influence of the C terminus of Wiskott-Aldrich syndrome protein (WASp) and the Arp2/3 complex on actin polymerization HN Higgs, L Blanchoin, TD Pollard Biochemistry 38 (46), 15212-15222, 1999 | 340 | 1999 |
A mitochondria-anchored isoform of the actin-nucleating spire protein regulates mitochondrial division U Manor, S Bartholomew, G Golani, E Christenson, M Kozlov, H Higgs, ... elife 4, e08828, 2015 | 319 | 2015 |
Actin filaments target the oligomeric maturation of the dynamin GTPase Drp1 to mitochondrial fission sites W Ji, AL Hatch, RA Merrill, S Strack, HN Higgs Elife 4, e11553, 2015 | 317 | 2015 |