| De Novo Drug Design of Targeted Chemical Libraries Based on Artificial Intelligence and Pair-Based Multiobjective Optimization A Domenico, G Nicola, T Daniela, C Fulvio, A Nicola, N Orazio Journal of Chemical Information and Modeling 60 (10), 4582-4593, 2020 | 66 | 2020 |
| FAD/NADH dependent oxidoreductases: from different amino acid sequences to similar protein shapes for playing an ancient function L Trisolini, N Gambacorta, R Gorgoglione, M Montaruli, L Laera, F Colella, ... Journal of Clinical Medicine 8 (12), 2117, 2019 | 46 | 2019 |
| Novel class of chalcone oxime ethers as potent monoamine oxidase-B and acetylcholinesterase inhibitors JM Oh, TM Rangarajan, R Chaudhary, RP Singh, M Singh, RP Singh, ... Molecules 25 (10), 2356, 2020 | 40 | 2020 |
| Piperazine-substituted chalcones: A new class of MAO-B, AChE, and BACE-1 inhibitors for the treatment of neurological disorders B Mathew, JM Oh, RS Baty, GES Batiha, DGT Parambi, N Gambacorta, ... Environmental science and pollution research 28, 38855-38866, 2021 | 38 | 2021 |
| Design, synthesis and biological evaluation of imidazole and triazole-based carbamates as novel aromatase inhibitors A Ammazzalorso, M Gallorini, M Fantacuzzi, N Gambacorta, B De Filippis, ... European Journal of Medicinal Chemistry 211, 113115, 2021 | 32 | 2021 |
| Morpholine-based chalcones as dual-acting monoamine oxidase-B and acetylcholinesterase inhibitors: Synthesis and biochemical investigations R Sasidharan, BH Eom, JH Heo, JE Park, MA Abdelgawad, A Musa, ... Journal of enzyme inhibition and medicinal chemistry 36 (1), 188-197, 2021 | 29 | 2021 |
| Halogenated coumarin–chalcones as multifunctional monoamine oxidase-B and butyrylcholinesterase inhibitors NA Rehuman, JM Oh, LR Nath, A Khames, MA Abdelgawad, ... ACS omega 6 (42), 28182-28193, 2021 | 27 | 2021 |
| Trimethoxylated halogenated chalcones as dual inhibitors of MAO-B and BACE-1 for the treatment of neurodegenerative disorders VP Koyiparambath, JM Oh, A Khames, MA Abdelgawad, AS Nair, LR Nath, ... Pharmaceutics 13 (6), 850, 2021 | 24 | 2021 |
| Selected 1, 3‐benzodioxine‐containing chalcones as multipotent oxidase and acetylcholinesterase inhibitors GS Jeong, S Kaipakasseri, SR Lee, N Marraiki, GES Batiha, S Dev, ... ChemMedChem 15 (23), 2257-2263, 2020 | 19 | 2020 |
| Design, synthesis and biological evaluation of aromatase inhibitors based on sulfonates and sulfonamides of resveratrol M Fantacuzzi, M Gallorini, N Gambacorta, A Ammazzalorso, Z Aturki, ... Pharmaceuticals 14 (10), 984, 2021 | 18 | 2021 |
| PLATO: A predictive drug discovery web platform for efficient target fishing and bioactivity profiling of small molecules F Ciriaco, N Gambacorta, D Trisciuzzi, O Nicolotti International Journal of Molecular Sciences 23 (9), 5245, 2022 | 17 | 2022 |
| Synthesis, structure-activity relationships and molecular docking studies of phenyldiazenyl sulfonamides as aromatase inhibitors L Giampietro, M Gallorini, N Gambacorta, A Ammazzalorso, B De Filippis, ... European Journal of Medicinal Chemistry 224, 113737, 2021 | 17 | 2021 |
| Quantitative polypharmacology profiling based on a multifingerprint similarity predictive approach F Ciriaco, N Gambacorta, D Alberga, O Nicolotti Journal of Chemical Information and Modeling 61 (10), 4868-4876, 2021 | 17 | 2021 |
| Design, synthesis and biological evaluation of 3, 5-diaryl isoxazole derivatives as potential anticancer agents DA Aktaş, G Akinalp, F Sanli, MA Yucel, N Gambacorta, O Nicolotti, ... Bioorganic & Medicinal Chemistry Letters 30 (19), 127427, 2020 | 16 | 2020 |
| Design, synthesis, and biological evaluation of pyridazinones containing the (2-fluorophenyl) piperazine moiety as selective MAO-B inhibitors M Çeçen, JM Oh, Z Özdemir, SE Büyüktuncel, M Uysal, MA Abdelgawad, ... Molecules 25 (22), 5371, 2020 | 15 | 2020 |
| Bcr-Abl allosteric inhibitors: where we are and where we are going to F Carofiglio, D Trisciuzzi, N Gambacorta, F Leonetti, A Stefanachi, ... Molecules 25 (18), 4210, 2020 | 15 | 2020 |
| TIRESIA: an explainable artificial intelligence platform for predicting developmental toxicity MV Togo, F Mastrolorito, F Ciriaco, D Trisciuzzi, AR Tondo, N Gambacorta, ... Journal of Chemical Information and Modeling 63 (1), 56-66, 2022 | 14 | 2022 |
| Development of halogenated-chalcones bearing with dimethoxy phenyl head as monoamine oxidase-B inhibitors NA Rehuman, JM Oh, MA Abdelgawad, EAM Beshr, MAS Abourehab, ... Pharmaceuticals 15 (9), 1152, 2022 | 13 | 2022 |
| A New Potent and Selective Monoamine Oxidase‐B Inhibitor with Extended Conjugation in a Chalcone Framework: 1‐[4‐(Morpholin‐4‐yl) phenyl]‐5‐phenylpenta‐2, 4‐dien‐1‐one N Maliyakkal, BH Eom, JH Heo, MA Abdullah Almoyad, ... ChemMedChem 15 (17), 1629-1633, 2020 | 13 | 2020 |
| Aldoxime-and hydroxy-functionalized chalcones as highly potent and selective monoamine oxidase-B inhibitors JM Oh, TM Rangarajan, R Chaudhary, N Gambacorta, O Nicolotti, ... Journal of Molecular Structure 1250, 131817, 2022 | 12 | 2022 |
