| Clustal W and Clustal X version 2.0 MA Larkin, G Blackshields, NP Brown, R Chenna, PA McGettigan, ... bioinformatics 23 (21), 2947-2948, 2007 | 32099 | 2007 |
| The genetic landscape of a cell M Costanzo, A Baryshnikova, J Bellay, Y Kim, ED Spear, CS Sevier, ... science 327 (5964), 425-431, 2010 | 2485 | 2010 |
| M-Coffee: combining multiple sequence alignment methods with T-Coffee IM Wallace, O O'sullivan, DG Higgins, C Notredame Nucleic acids research 34 (6), 1692-1699, 2006 | 664 | 2006 |
| Highly-multiplexed barcode sequencing: an efficient method for parallel analysis of pooled samples AM Smith, LE Heisler, RP St. Onge, E Farias-Hesson, IM Wallace, ... Nucleic acids research 38 (13), e142-e142, 2010 | 264 | 2010 |
| Mapping the cellular response to small molecules using chemogenomic fitness signatures AY Lee, RP St. Onge, MJ Proctor, IM Wallace, AH Nile, PA Spagnuolo, ... Science 344 (6180), 208-211, 2014 | 261 | 2014 |
| The M-Coffee web server: a meta-method for computing multiple sequence alignments by combining alternative alignment methods S Moretti, F Armougom, IM Wallace, DG Higgins, CV Jongeneel, ... Nucleic acids research 35 (suppl_2), W645-W648, 2007 | 259 | 2007 |
| An integrated platform of genomic assays reveals small-molecule bioactivities S Hoon, A M Smith, IM Wallace, S Suresh, M Miranda, E Fung, M Proctor, ... Nature chemical biology 4 (8), 498-506, 2008 | 216 | 2008 |
| A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans AR Burns, IM Wallace, J Wildenhain, M Tyers, G Giaever, GD Bader, ... Nature chemical biology 6 (7), 549-557, 2010 | 199 | 2010 |
| Multiple sequence alignments IM Wallace, G Blackshields, DG Higgins Current opinion in structural biology 15 (3), 261-266, 2005 | 167 | 2005 |
| Dark chemical matter as a promising starting point for drug lead discovery AM Wassermann, E Lounkine, D Hoepfner, G Le Goff, FJ King, C Studer, ... Nature chemical biology 11 (12), 958-966, 2015 | 134 | 2015 |
| Analysis and comparison of benchmarks for multiple sequence alignment G Blackshields, IM Wallace, M Larkin, DG Higgins In silico biology 6 (4), 321-339, 2006 | 106 | 2006 |
| Evaluation of iterative alignment algorithms for multiple alignment IM Wallace, DG Higgins Bioinformatics 21 (8), 1408-1414, 2005 | 95 | 2005 |
| Open source drug discovery: highly potent antimalarial compounds derived from the tres cantos arylpyrroles AE Williamson, PM Ylioja, MN Robertson, Y Antonova-Koch, V Avery, ... ACS central science 2 (10), 687-701, 2016 | 81 | 2016 |
| Target Prediction for an Open Access Set of Compounds Active against Mycobacterium tuberculosis F Martinez-Jimenez, G Papadatos, L Yang, IM Wallace, V Kumar, ... PLOS computational biology 9 (10), e1003253, 2013 | 65 | 2013 |
| Compound prioritization methods increase rates of chemical probe discovery in model organisms IM Wallace, ML Urbanus, GM Luciani, AR Burns, MKL Han, H Wang, ... Chemistry & biology 18 (10), 1273-1283, 2011 | 56 | 2011 |
| PITPs as targets for selectively interfering with phosphoinositide signaling in cells AH Nile, A Tripathi, P Yuan, CJ Mousley, S Suresh, IM Wallace, SD Shah, ... Nature chemical biology 10 (1), 76-84, 2014 | 55 | 2014 |
| Dafadine inhibits DAF-9 to promote dauer formation and longevity of Caenorhabditis elegans GM Luciani, L Magomedova, R Puckrin, ML Urbanus, IM Wallace, ... Nature Chemical Biology 7 (12), 891-893, 2011 | 33 | 2011 |
| Supervised multivariate analysis of sequence groups to identify specificity determining residues IM Wallace, DG Higgins Bmc Bioinformatics 8, 1-12, 2007 | 28 | 2007 |
| Mind the gaps: progress in progressive alignment DG Higgins, G Blackshields, IM Wallace Proceedings of the National Academy of Sciences 102 (30), 10411-10412, 2005 | 26 | 2005 |
| Discovery of a small molecule RXFP3/4 agonist that increases food intake in rats upon acute central administration B DeChristopher, SH Park, L Vong, D Bamford, HH Cho, R Duvadie, ... Bioorganic & medicinal chemistry letters 29 (8), 991-994, 2019 | 24 | 2019 |
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