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Prakasha Kempaiah, PhD
Prakasha Kempaiah, PhD
Associate Consultant, Mayo Clinic, Jacksonville, Florida
Verified email at mayo.edu - Homepage
Title
Cited by
Cited by
Year
Severe malarial anemia: innate immunity and pathogenesis
DJ Perkins, T Were, GC Davenport, P Kempaiah, JB Hittner, JM Ong'echa
International journal of biological sciences 7 (9), 1427, 2011
4092011
Natural infection of Plasmodium brasilianum in humans: man and monkey share quartan malaria parasites in the Venezuelan Amazon
A Lalremruata, M Magris, S Vivas-Martínez, M Koehler, M Esen, ...
EBioMedicine 2 (9), 1186-1192, 2015
1652015
Discovery of New Hydroxyethylamine Analogs against 3CLpro Protein Target of SARS-CoV-2: Molecular Docking, Molecular Dynamics Simulation, and Structure–Activity Relationship …
S Kumar, PP Sharma, U Shankar, D Kumar, SK Joshi, L Pena, ...
J. Chem. Inf. Model, 2020
1172020
Mycobacterium abscessus glycopeptidolipid prevents respiratory epithelial TLR2 signaling as measured by HβD2 gene expression and IL-8 release
LB Davidson, R Nessar, P Kempaiah, DJ Perkins, TF Byrd
PloS one 6 (12), e29148, 2011
712011
Mechanisms of erythropoiesis inhibition by malarial pigment and malaria‐induced proinflammatory mediators in an in vitro model
GA Awandare, P Kempaiah, DO Ochiel, P Piazza, CC Keller, DJ Perkins
American journal of hematology 86 (2), 155-162, 2011
672011
A review of the preclinical and clinical efficacy of remdesivir, hydroxychloroquine, and lopinavir-ritonavir treatments against COVID-19
D Maciorowski, SZE Idrissi, Y Gupta, BJ Medernach, MB Burns, ...
SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (10), 1108-1122, 2020
402020
Human tissue factor pathway inhibitor-2 induces caspase-mediated apoptosis in a human fibrosarcoma cell line
P Kempaiah, W Kisiel
Apoptosis 13, 702-715, 2008
382008
Identification of a human TFPI-2 splice variant that is upregulated in human tumor tissues
P Kempaiah, HS Chand, W Kisiel
Molecular cancer 6, 1-11, 2007
362007
Functional haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children
C Ouma, GC Davenport, S Garcia, P Kempaiah, A Chaudhary, T Were, ...
Human genetics 131, 289-299, 2012
352012
Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening pipeline and in-vitro validation assays
Y Gupta, D Maciorowski, SE Zak, KA Jones, RS Kathayat, SA Azizi, ...
Methods 195, 57-71, 2021
332021
Fluorinated scaffolds for antimalarial drug discovery
C Upadhyay, M Chaudhary, RN De Oliveira, A Borbas, P Kempaiah, P S, ...
Expert Opinion on Drug Discovery 15 (6), 705-718, 2020
332020
Heparin: A simplistic repurposing to prevent SARS-CoV-2 transmission in light of its in-vitro nanomolar efficacy
Y Gupta, D Maciorowski, SE Zak, CV Kulkarni, AS Herbert, R Durvasula, ...
International Journal of Biological Macromolecules 183, 203-212, 2021
292021
Antiplasmodial activity of hydroxyethylamine analogs: synthesis, biological activity and structure activity relationship of plasmepsin inhibitors
AK Singh, V Rajendran, S Singh, P Kumar, Y Kumar, A Singh, W Miller, ...
Bioorganic & medicinal chemistry 26 (13), 3837-3844, 2018
282018
Iron dysregulation in COVID‐19 and reciprocal evolution of SARS‐CoV‐2: Natura nihil frustra facit
Y Gupta, D Maciorowski, B Medernach, DP Becker, R Durvasula, ...
Journal of Cellular Biochemistry, 2022
242022
A novel compound active against SARS-CoV-2 targeting uridylate-specific endoribonuclease (NendoU/NSP15): in silico and in vitro investigations
S Kumar, Y Gupta, SE Zak, C Upadhyay, N Sharma, AS Herbert, ...
RSC Medicinal Chemistry 12 (10), 1757-1764, 2021
242021
Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics
Y Gupta, OV Savytskyi, M Coban, A Venugopal, V Pleqi, CA Weber, ...
Molecular Aspects of Medicine 91, 101151, 2023
232023
Reduced parasite burden in children with falciparum malaria and bacteremia coinfections: role of mediators of inflammation
GC Davenport, JB Hittner, V Otieno, Z Karim, H Mukundan, PW Fenimore, ...
Mediators of inflammation 2016, 2016
222016
Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality
SB Anyona, P Kempaiah, E Raballah, C Ouma, T Were, GC Davenport, ...
Infection and immunity 79 (12), 4923-4932, 2011
222011
Fast-acting small molecules targeting malarial aspartyl proteases, plasmepsins, inhibit malaria infection at multiple life stages
S Singh, V Rajendran, J He, AK Singh, AO Achieng, Vandana, A Pant, ...
ACS Infectious Diseases 5 (2), 184-198, 2018
212018
Reduced Hsp70 and glutamine in pediatric severe malaria anemia: role of hemozoin in suppressing Hsp70 and NF-κB activation
P Kempaiah, K Dokladny, Z Karim, E Raballah, JM Ong’echa, PL Moseley, ...
Molecular Medicine 22, 570-584, 2016
212016
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