Konstanze Winklhofer
Konstanze Winklhofer
Onbekend partnerschap
Geverifieerd e-mailadres voor ruhr-uni-bochum.de
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin
N Exner, B Treske, D Paquet, K Holmström, C Schiesling, S Gispert, ...
Journal of Neuroscience 27 (45), 12413-12418, 2007
Mitochondrial dysfunction in Parkinson's disease
KF Winklhofer, C Haass
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1802 (1), 29-44, 2010
Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences
N Exner, AK Lutz, C Haass, KF Winklhofer
The EMBO journal 31 (14), 3038-3062, 2012
Inhibition of mitochondrial fusion by α‐synuclein is rescued by PINK1, Parkin and DJ‐1
F Kamp, N Exner, AK Lutz, N Wender, J Hegermann, B Brunner, ...
The EMBO journal 29 (20), 3571-3589, 2010
Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation
AK Lutz, N Exner, ME Fett, JS Schlehe, K Kloos, K Lämmermann, ...
Journal of Biological Chemistry 284 (34), 22938-22951, 2009
The two faces of protein misfolding: gain‐and loss‐of‐function in neurodegenerative diseases
KF Winklhofer, J Tatzelt, C Haass
The EMBO journal 27 (2), 336-349, 2008
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
I Irrcher, H Aleyasin, EL Seifert, SJ Hewitt, S Chhabra, M Phillips, AK Lutz, ...
Human molecular genetics 19 (19), 3734-3746, 2010
Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA
AC Woerner, F Frottin, D Hornburg, LR Feng, F Meissner, M Patra, ...
Science 351 (6269), 173-176, 2016
Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress
L Bouman, A Schlierf, AK Lutz, J Shan, A Deinlein, J Kast, Z Galehdar, ...
Cell Death & Differentiation 18 (5), 769-782, 2011
The cellular prion protein mediates neurotoxic signalling of β‐sheet‐rich conformers independent of prion replication
UK Resenberger, A Harmeier, AC Woerner, JL Goodman, V Müller, ...
The EMBO journal 30 (10), 2057-2070, 2011
Parkin mediates neuroprotection through activation of IκB kinase/nuclear factor-κB signaling
IH Henn, L Bouman, JS Schlehe, A Schlierf, JE Schramm, E Wegener, ...
Journal of Neuroscience 27 (8), 1868-1878, 2007
Intracellular re‐routing of prion protein prevents propagation of PrPSc and delays onset of prion disease
S Gilch, KF Winklhofer, MH Groschup, M Nunziante, R Lucassen, ...
The EMBO journal 20 (15), 3957-3966, 2001
The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO
AK Müller-Rischart, A Pilsl, P Beaudette, M Patra, K Hadian, M Funke, ...
Molecular cell 49 (5), 908-921, 2013
Inflammation-induced alteration of astrocyte mitochondrial dynamics requires autophagy for mitochondrial network maintenance
E Motori, J Puyal, N Toni, A Ghanem, C Angeloni, M Malaguti, ...
Cell metabolism 18 (6), 844-859, 2013
Inactivation of parkin by oxidative stress and C-terminal truncations: a protective role of molecular chaperones
KF Winklhofer, IH Henn, PC Kay-Jackson, U Heller, J Tatzelt
Journal of Biological Chemistry 278 (47), 47199-47208, 2003
Parkin and mitochondrial quality control: toward assembling the puzzle
KF Winklhofer
Trends in cell biology 24 (6), 332-341, 2014
Parkin, PINK1 and mitochondrial integrity: emerging concepts of mitochondrial dysfunction in Parkinson’s disease
A Pilsl, KF Winklhofer
Acta neuropathologica 123 (2), 173-188, 2012
Stress‐protective signalling of prion protein is corrupted by scrapie prions
AS Rambold, V Müller, U Ron, N Ben‐Tal, KF Winklhofer, J Tatzelt
The EMBO journal 27 (14), 1974-1984, 2008
Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system
A Brychzy, T Rein, KF Winklhofer, FU Hartl, JC Young, WMJ Obermann
The EMBO journal 22 (14), 3613-3623, 2003
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Artikelen 1–20