| Human Homolog of patched, a Candidate Gene for the Basal Cell Nevus Syndrome RL Johnson, AL Rothman, J Xie, LV Goodrich, JW Bare, JM Bonifas, ... Science 272 (5268), 1668-1671, 1996 | 2338 | 1996 |
| Activating Smoothened mutations in sporadic basal-cell carcinoma J Xie, M Murone, SM Luoh, A Ryan, Q Gu, C Zhang, JM Bonifas, CW Lam, ... Nature 391 (6662), 90-92, 1998 | 1623 | 1998 |
| Activation of the hedgehog-signaling pathway in human cancer and the clinical implications L Yang, G Xie, Q Fan, J Xie Oncogene 29 (4), 469-481, 2010 | 410 | 2010 |
| Mutations of the PATCHED Gene in Several Types of Sporadic Extracutaneous Tumors J Xie, RL Johnson, X Zhang, JW Bare, FM Waldman, PH Cogen, ... Cancer research 57 (12), 2369-2372, 1997 | 401 | 1997 |
| Activation of the hedgehog pathway in advanced prostate cancer T Sheng, C Li, X Zhang, S Chi, N He, K Chen, F McCormick, Z Gatalica, ... Molecular cancer 3, 1-13, 2004 | 390 | 2004 |
| Identification of mutations in the human PATCHED gene in sporadic basal cell carcinomas and in patients with the basal cell nevus syndrome M Aszterbaum, A Rothman, M Fisher, J Xie, JM Bonifas, X Zhang, ... Journal of investigative dermatology 110 (6), 885-888, 1998 | 370 | 1998 |
| Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells Z Ji, FC Mei, J Xie, X Cheng Journal of Biological Chemistry 282 (19), 14048-14055, 2007 | 356 | 2007 |
| Activation of the hedgehog pathway in human hepatocellular carcinomas S Huang, J He, X Zhang, Y Bian, L Yang, G Xie, K Zhang, W Tang, ... Carcinogenesis 27 (7), 1334-1340, 2006 | 325 | 2006 |
| Abrogating cholesterol esterification suppresses growth and metastasis of pancreatic cancer J Li, D Gu, SSY Lee, B Song, S Bandyopadhyay, S Chen, SF Konieczny, ... Oncogene 35 (50), 6378-6388, 2016 | 255 | 2016 |
| A frequent activated smoothened mutation in sporadic basal cell carcinomas CW Lam, J Xie, KF To, HK Ng, KC Lee, NWF Yuen, PL Lim, LYS Chan, ... Oncogene 18 (3), 833-836, 1999 | 255 | 1999 |
| Frequent activation of the hedgehog pathway in advanced gastric adenocarcinomas X Ma, K Chen, S Huang, X Zhang, PA Adegboyega, BM Evers, H Zhang, ... Carcinogenesis 26 (10), 1698-1705, 2005 | 250 | 2005 |
| A role of PDGFRα in basal cell carcinoma proliferation J Xie, M Aszterbaum, X Zhang, JM Bonifas, C Zachary, E Epstein, ... Proceedings of the National Academy of Sciences 98 (16), 9255-9259, 2001 | 241 | 2001 |
| Inhibition of Smoothened Signaling Prevents Ultraviolet B-Induced Basal Cell Carcinomas through Regulation of Fas Expression and Apoptosis M Athar, C Li, X Tang, S Chi, X Zhang, AL Kim, SK Tyring, L Kopelovich, ... Cancer research 64 (20), 7545-7552, 2004 | 230 | 2004 |
| Hedgehog signaling is activated in subsets of esophageal cancers X Ma, T Sheng, Y Zhang, X Zhang, J He, S Huang, K Chen, J Sultz, ... International journal of cancer 118 (1), 139-148, 2006 | 221 | 2006 |
| Suppressing Wnt signaling by the hedgehog pathway through sFRP-1 J He, T Sheng, AA Stelter, C Li, X Zhang, M Sinha, BA Luxon, J Xie Journal of Biological Chemistry 281 (47), 35598-35602, 2006 | 177 | 2006 |
| Identification of a large Myc-binding protein that contains RCC1-like repeats Q Guo, J Xie, CV Dang, ET Liu, JM Bishop Proceedings of the National Academy of Sciences 95 (16), 9172-9177, 1998 | 163 | 1998 |
| Regulatory Role of Human AP-Endonuclease (APE1/Ref-1) in YB-1-Mediated Activation of the Multidrug Resistance Gene MDR1 R Chattopadhyay, S Das, AK Maiti, I Boldogh, J Xie, TK Hazra, K Kohno, ... Molecular and cellular biology 28 (23), 7066-7080, 2008 | 154 | 2008 |
| The Hedgehog pathway: role in cell differentiation, polarity and proliferation Y Jia, Y Wang, J Xie Archives of toxicology 89, 179-191, 2015 | 149 | 2015 |
| Regulation of Gli1 localization by the cAMP/protein kinase A signaling axis through a site near the nuclear localization signal T Sheng, S Chi, X Zhang, J Xie Journal of Biological Chemistry 281 (1), 9-12, 2006 | 142 | 2006 |
| Promising molecular mechanisms responsible for gemcitabine resistance in cancer Y Jia, J Xie Genes & Diseases 2 (4), 299-306, 2015 | 136 | 2015 |
Guorui XieUCSFGeverifieerd e-mailadres voor gladstone.ucsf.edu
