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Daniel Dauch
Daniel Dauch
Department of Medical Oncology and Pneumology, University Hospital Tuebingen, Tuebingen, Germany
Verified email at med.uni-tuebingen.de
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Cited by
Cited by
Year
Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
TW Kang, T Yevsa, N Woller, L Hoenicke, T Wuestefeld, D Dauch, ...
Nature 479 (7374), 547-551, 2011
15562011
A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage
J Wang, Q Sun, Y Morita, H Jiang, A Groß, A Lechel, K Hildner, ...
Cell 148 (5), 1001-1014, 2012
3752012
Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer
M Malehmir, D Pfister, S Gallage, M Szydlowska, D Inverso, E Kotsiliti, ...
Nature medicine 25 (4), 641-655, 2019
3182019
In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer
R Rudalska, D Dauch, T Longerich, K McJunkin, T Wuestefeld, TW Kang, ...
Nature medicine 20 (10), 1138-1146, 2014
3022014
A MYC–aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer
D Dauch, R Rudalska, G Cossa, JC Nault, TW Kang, T Wuestefeld, ...
Nature medicine 22 (7), 744-753, 2016
2722016
Cardiac glycosides are broad-spectrum senolytics
A Guerrero, N Herranz, B Sun, V Wagner, S Gallage, R Guiho, K Wolter, ...
Nature metabolism 1 (11), 1074-1088, 2019
2492019
A critical role for notch signaling in the formation of cholangiocellular carcinomas
S Zender, I Nickeleit, T Wuestefeld, I Sörensen, D Dauch, P Bozko, ...
Cancer cell 23 (6), 784-795, 2013
2352013
A Direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration
T Wuestefeld, M Pesic, R Rudalska, D Dauch, T Longerich, TW Kang, ...
Cell 153 (2), 389-401, 2013
1662013
IGF2 is up-regulated by epigenetic mechanisms in hepatocellular carcinomas and is an actionable oncogene product in experimental models
I Martinez-Quetglas, R Pinyol, D Dauch, S Torrecilla, V Tovar, A Moeini, ...
Gastroenterology 151 (6), 1192-1205, 2016
1202016
Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathways in tumours
E Brenner, BF Schörg, F Ahmetlić, T Wieder, FJ Hilke, N Simon, ...
Nature Communications 11 (1), 1335, 2020
952020
Spatial tissue proteomics quantifies inter-and intratumor heterogeneity in hepatocellular carcinoma (HCC)
K Buczak, A Ori, JM Kirkpatrick, K Holzer, D Dauch, S Roessler, V Endris, ...
Molecular & Cellular Proteomics 17 (4), 810-825, 2018
792018
Assessment of mutation probabilities of KRAS G12 missense mutants and their long-timescale dynamics by atomistic molecular simulations and Markov state modeling
T Pantsar, S Rissanen, D Dauch, T Laitinen, I Vattulainen, A Poso
PLoS computational biology 14 (9), e1006458, 2018
742018
Nucleoporin Nup155 is part of the p53 network in liver cancer
K Holzer, A Ori, A Cooke, D Dauch, E Drucker, P Riemenschneider, ...
Nature communications 10 (1), 2147, 2019
392019
Proteomic analysis reveals GMP synthetase as p53 repression target in liver cancer
K Holzer, E Drucker, S Roessler, D Dauch, F Heinzmann, N Waldburger, ...
The American journal of pathology 187 (2), 228-235, 2017
372017
Prosurvival function of the cellular apoptosis susceptibility/importin‐α1 transport cycle is repressed by p53 in liver cancer
J Winkler, A Ori, K Holzer, C Sticht, D Dauch, EM Eiteneuer, F Pinna, ...
Hepatology 60 (3), 884-895, 2014
352014
Optimized Target Residence Time: Type I Inhibitors for p38α MAP Kinase with Improved Binding Kinetics through Direct Interaction with the R‐Spine
HK Wentsch, NM Walter, M Bührmann, S Mayer‐Wrangowski, D Rauh, ...
Angewandte Chemie International Edition 56 (19), 5363-5367, 2017
302017
LXRα activation and Raf inhibition trigger lethal lipotoxicity in liver cancer
R Rudalska, J Harbig, MT Snaebjornsson, S Klotz, S Zwirner, L Taranets, ...
Nature cancer 2 (2), 201-217, 2021
272021
Selective targeting of the αC and DFG-out pocket in p38 MAPK
S Roehm, M Schroeder, JE Dwyer, CS Widdowson, A Chaikuad, ...
European Journal of Medicinal Chemistry 208, 112721, 2020
132020
MYC determines lineage commitment in KRAS-driven primary liver cancer development
L D’Artista, AA Moschopoulou, I Barozzi, AJ Craig, M Seehawer, ...
Journal of Hepatology 79 (1), 141-149, 2023
62023
HELLS is negatively regulated by wild-type P53 in liver cancer by a mechanism involving P21 and FOXM1
S Schuller, J Sieker, P Riemenschneider, B Köhler, E Drucker, ...
Cancers 14 (2), 459, 2022
62022
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