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Utkrisht C Rajkumar
Utkrisht C Rajkumar
Machine Learning Scientist at Amazon
Geverifieerd e-mailadres voor ucsd.edu
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Circular ecDNA promotes accessible chromatin and high oncogene expression
S Wu, KM Turner, N Nguyen, R Raviram, M Erb, J Santini, J Luebeck, ...
Nature 575 (7784), 699-703, 2019
3922019
Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers
H Kim, NP Nguyen, K Turner, S Wu, AD Gujar, J Luebeck, J Liu, ...
Nature genetics 52 (9), 891-897, 2020
2982020
NAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodelling
S Chowdhry, C Zanca, U Rajkumar, T Koga, Y Diao, R Raviram, F Liu, ...
Nature 569 (7757), 570-575, 2019
1822019
ecDNA hubs drive cooperative intermolecular oncogene expression
KL Hung, KE Yost, L Xie, Q Shi, K Helmsauer, J Luebeck, R Schöpflin, ...
Nature 600 (7890), 731-736, 2021
1472021
AmpliconReconstructor integrates NGS and optical mapping to resolve the complex structures of focal amplifications
J Luebeck, C Coruh, SR Dehkordi, JT Lange, KM Turner, V Deshpande, ...
Nature communications 11 (1), 4374, 2020
632020
The evolutionary dynamics of extrachromosomal DNA in human cancers
JT Lange, JC Rose, CY Chen, Y Pichugin, L Xie, J Tang, KL Hung, ...
Nature genetics 54 (10), 1527-1533, 2022
582022
EcSeg: semantic segmentation of metaphase images containing extrachromosomal DNA
U Rajkumar, K Turner, J Luebeck, V Deshpande, M Chandraker, ...
Iscience 21, 428-435, 2019
322019
Principles of ecDNA random inheritance drive rapid genome change and therapy resistance in human cancers
JT Lange, CY Chen, Y Pichugin, L Xie, J Tang, KL Hung, KE Yost, Q Shi, ...
BioRxiv, 2021.06. 11.447968, 2021
162021
DeepViFi: detecting oncoviral infections in cancer genomes using transformers
U Rajkumar, S Javadzadeh, M Bafna, D Wu, R Yu, J Shang, V Bafna
Proceedings of the 13th ACM International Conference on Bioinformatics …, 2022
52022
Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma
OS Chapman, J Luebeck, S Sridhar, ITL Wong, D Dixit, S Wang, G Prasad, ...
Nature genetics 55 (12), 2189-2199, 2023
42023
Fastvifi: fast and accurate detection of (hybrid) viral DNA and RNA
S Javadzadeh, U Rajkumar, N Nguyen, S Sarmashghi, J Luebeck, ...
NAR Genomics and Bioinformatics 4 (2), lqac032, 2022
22022
A CNN-based cell tracking method for multi-slice intravital imaging data
K Fujimoto, T Mizugaki, U Rajkumar, H Shigeta, S Seno, Y Uchida, M Ishii, ...
Proceedings of the 12th ACM Conference on Bioinformatics, Computational …, 2021
12021
Permutations resilient to deletions
N Alon, S Butler, R Graham, UC Rajkumar
Annals of Combinatorics 22, 673-680, 2018
12018
Breakage fusion bridge cycles drive high oncogene copy number, but not intratumoral genetic heterogeneity or rapid cancer genome change
SR Dehkordi, ITL Wong, J Ni, J Luebeck, K Zhu, G Prasad, ...
bioRxiv, 2023
2023
Deep Learning in Cancer Biology
UC Rajkumar
2022
Methods of treating extrachromosomal dna expressing cancers
P Mischel, V Bafna, J Ko, W Zhang, U Rajkumar
2019
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Artikelen 1–16