Helix propensities of the amino acids measured in alanine‐based peptides without helix‐stabilizing side‐chain interactions A Chakrabartty, T Kortemme, RL Baldwin Protein Science 3 (5), 843-852, 1994 | 819 | 1994 |
Stability of α-helices A Chakrabartty, RL Baldwin Advances in protein chemistry 46, 141-176, 1995 | 547 | 1995 |
Membrane disruption by Alzheimer β-amyloid peptides mediated through specific binding to either phospholipids or gangliosides JA McLaurin, A Chakrabartty Journal of Biological Chemistry 271 (43), 26482-26489, 1996 | 437 | 1996 |
Large differences in the helix propensities of alanine and glycine A Chakrabartty, JA Schellman, RL Baldwin Nature 351 (6327), 586-588, 1991 | 426 | 1991 |
Oxidation-induced misfolding and aggregation of superoxide dismutase and its implications for amyotrophic lateral sclerosis R Rakhit, P Cunningham, A Furtos-Matei, S Dahan, XF Qi, JP Crow, ... Journal of Biological Chemistry 277 (49), 47551-47556, 2002 | 417 | 2002 |
Aromatic side-chain contribution to far-ultraviolet circular dichroism of helical peptides and its effect on measurement of helix propensities A Chakrabartty, T Kortemme, S Padmanabhan, RL Baldwin Biochemistry 32 (21), 5560-5565, 1993 | 417 | 1993 |
Monomeric Cu, Zn-superoxide Dismutase Is a Common Misfolding Intermediate in the Oxidation Models of Sporadic and Familial Amyotrophic Lateral Sclerosis*[boxs] R Rakhit, JP Crow, JR Lepock, LH Kondejewski, NR Cashman, ... Journal of Biological Chemistry 279 (15), 15499-15504, 2004 | 409 | 2004 |
A prion protein epitope selective for the pathologically misfolded conformation LA Zou, J Lamontagne, MT Lehto, LH Kondejewski, GP Francoeur, ... Nature medicine 9 (7), 893, 2003 | 356 | 2003 |
Helix propagation and N‐cap propensities of the amino acids measured in alanine‐based peptides in 40 volume percent trifluoroethanol CA Rohl, A Chakrabartty, RL Baldwin Protein Science 5 (12), 2623-2637, 1996 | 351 | 1996 |
Crystal structure of an antifreeze polypeptide and its mechanistic implications DSC Yang, M Sax, A Chakrabartty, CL Hew Nature 333 (6170), 232-237, 1988 | 349 | 1988 |
Manipulating the amyloid-β aggregation pathway with chemical chaperones DS Yang, CM Yip, THJ Huang, A Chakrabartty, PE Fraser Journal of Biological Chemistry 274 (46), 32970-32974, 1999 | 334 | 1999 |
Helix capping propensities in peptides parallel those in proteins. A Chakrabartty, AJ Doig, RL Baldwin Proceedings of the National Academy of Sciences 90 (23), 11332-11336, 1993 | 310 | 1993 |
An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS R Rakhit, J Robertson, CV Velde, P Horne, DM Ruth, J Griffin, ... Nature medicine 13 (6), 754-759, 2007 | 296 | 2007 |
Characterization of the interactions of Alzheimer β‐amyloid peptides with phospholipid membranes JA McLaurin, A Chakrabartty European Journal of Biochemistry 245 (2), 355-363, 1997 | 263 | 1997 |
Amyotrophic lateral sclerosis is a non-amyloid disease in which extensive misfolding of SOD1 is unique to the familial form A Kerman, HN Liu, S Croul, J Bilbao, E Rogaeva, L Zinman, J Robertson, ... Acta neuropathologica 119, 335-344, 2010 | 261 | 2010 |
Structural studies of soluble oligomers of the Alzheimer β-amyloid peptide THJ Huang, DS Yang, NP Plaskos, S Go, CM Yip, PE Fraser, ... Journal of molecular biology 297 (1), 73-87, 2000 | 259 | 2000 |
Structure, folding, and misfolding of Cu, Zn superoxide dismutase in amyotrophic lateral sclerosis R Rakhit, A Chakrabartty Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1762 (11-12 …, 2006 | 256 | 2006 |
Determination of free energies of N-Capping in. alpha.-helixes by modification of the Lifson-Roig Helix-Coil theory to include N-and C-Capping AJ Doig, A Chakrabartty, TM Klingler, RL Baldwin Biochemistry 33 (11), 3396-3403, 1994 | 239 | 1994 |
Lipopeptide detergents designed for the structural study of membrane proteins CL McGregor, L Chen, NC Pomroy, P Hwang, S Go, A Chakrabartty, ... Nature biotechnology 21 (2), 171-176, 2003 | 229 | 2003 |
Structural transitions associated with the interaction of Alzheimer β-amyloid peptides with gangliosides JA McLaurin, T Franklin, PE Fraser, A Chakrabartty Journal of Biological Chemistry 273 (8), 4506-4515, 1998 | 225 | 1998 |