| Stellate cells, hepatocytes, and endothelial cells imprint the Kupffer cell identity on monocytes colonizing the liver macrophage niche J Bonnardel, W T’Jonck, D Gaublomme, R Browaeys, CL Scott, L Martens, ... Immunity 51 (4), 638-654. e9, 2019 | 433 | 2019 |
| A role for autophagy during hepatic stellate cell activation LFR Thoen, ELM Guimarães, L Dollé, I Mannaerts, M Najimi, E Sokal, ... Journal of hepatology 55 (6), 1353-1360, 2011 | 398 | 2011 |
| The Hippo pathway effector YAP controls mouse hepatic stellate cell activation I Mannaerts, SB Leite, S Verhulst, S Claerhout, N Eysackers, LFR Thoen, ... Journal of hepatology 63 (3), 679-688, 2015 | 345 | 2015 |
| Novel human hepatic organoid model enables testing of drug-induced liver fibrosis in vitro SB Leite, T Roosens, A El Taghdouini, I Mannaerts, AJ Smout, M Najimi, ... Biomaterials 78, 1-10, 2016 | 230 | 2016 |
| FXR agonist obeticholic acid reduces hepatic inflammation and fibrosis in a rat model of toxic cirrhosis L Verbeke, I Mannaerts, R Schierwagen, O Govaere, S Klein, ... Scientific reports 6 (1), 1-12, 2016 | 201 | 2016 |
| Generation of hepatic stellate cells from human pluripotent stem cells enables in vitro modeling of liver fibrosis M Coll, L Perea, R Boon, SB Leite, J Vallverdú, I Mannaerts, A Smout, ... Cell stem cell 23 (1), 101-113. e7, 2018 | 200 | 2018 |
| Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice IM Moya, SA Castaldo, L Van den Mooter, S Soheily, L Sansores-Garcia, ... Science 366 (6468), 1029-1034, 2019 | 154 | 2019 |
| Chronic administration of valproic acid inhibits activation of mouse hepatic stellate cells in vitro and in vivo I Mannaerts, NR Nuytten, V Rogiers, K Vanderkerken, LA van Grunsven, ... Hepatology 51 (2), 603-614, 2010 | 135 | 2010 |
| Valproic acid attenuates proteinuria and kidney injury K Van Beneden, C Geers, M Pauwels, I Mannaerts, D Verbeelen, ... Journal of the American Society of Nephrology 22 (10), 1863-1875, 2011 | 132 | 2011 |
| Integrative miRNA and gene expression profiling analysis of human quiescent hepatic stellate cells M Coll, AE Taghdouini, L Perea, I Mannaerts, M Vila-Casadesús, D Blaya, ... Scientific Reports 5 (1), 11549, 2015 | 98 | 2015 |
| HDAC inhibitors in experimental liver and kidney fibrosis K Van Beneden, I Mannaerts, M Pauwels, C Van den Branden, ... Fibrogenesis & tissue repair 6, 1-14, 2013 | 87 | 2013 |
| Class II HDAC inhibition hampers hepatic stellate cell activation by induction of microRNA-29 I Mannaerts, N Eysackers, OO Onyema, K Van Beneden, S Valente, A Mai, ... PloS one 8 (1), e55786, 2013 | 79 | 2013 |
| Genome-wide analysis of DNA methylation and gene expression patterns in purified, uncultured human liver cells and activated hepatic stellate cells A El Taghdouini, AL Sørensen, AH Reiner, M Coll, S Verhulst, I Mannaerts, ... Oncotarget 6 (29), 26729, 2015 | 67 | 2015 |
| Circulating ECV-associated miRNAs as potential clinical biomarkers in early stage HBV and HCV induced liver fibrosis J Lambrecht, P Jan Poortmans, S Verhulst, H Reynaert, I Mannaerts, ... Frontiers in pharmacology 8, 56, 2017 | 57 | 2017 |
| Comparison of trichostatin A and valproic acid treatment regimens in a mouse model of kidney fibrosis K Van Beneden, C Geers, M Pauwels, I Mannaerts, KM Wissing, ... Toxicology and applied pharmacology 271 (2), 276-284, 2013 | 57 | 2013 |
| Prospects in non-invasive assessment of liver fibrosis: Liquid biopsy as the future gold standard? J Lambrecht, S Verhulst, I Mannaerts, H Reynaert, LA van Grunsven Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (4 …, 2018 | 54 | 2018 |
| Gene expression profiling of early hepatic stellate cell activation reveals a role for Igfbp3 in cell migration I Mannaerts, B Schroyen, S Verhulst, L Van Lommel, F Schuit, M Nyssen, ... PloS one 8 (12), e84071, 2013 | 50 | 2013 |
| The role of miRNAs in stress-responsive hepatic stellate cells during liver fibrosis J Lambrecht, I Mannaerts, LA van Grunsven Frontiers in physiology 6, 150919, 2015 | 47 | 2015 |
| In vivo hepatocyte MR imaging using lactose functionalized magnetoliposomes A Ketkar-Atre, T Struys, T Dresselaers, M Hodenius, I Mannaerts, Y Ni, ... Biomaterials 35 (3), 1015-1024, 2014 | 38 | 2014 |
| A PDGFRβ-based score predicts significant liver fibrosis in patients with chronic alcohol abuse, NAFLD and viral liver disease J Lambrecht, S Verhulst, I Mannaerts, JP Sowa, J Best, A Canbay, ... EBioMedicine 43, 501-512, 2019 | 32 | 2019 |
Leo van GrunsvenProfessor @ Vrije Universiteit BrusselVerified email at vub.be
