Pamela McLean
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium
IG McKeith, BF Boeve, DW Dickson, G Halliday, JP Taylor, D Weintraub, ...
Neurology 89 (1), 88-100, 2017
Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies
JR Mazzulli, YH Xu, Y Sun, AL Knight, PJ McLean, GA Caldwell, ...
Cell 146 (1), 37-52, 2011
Sirtuin 2 inhibitors rescue α-synuclein-mediated toxicity in models of Parkinson's disease
TF Outeiro, E Kontopoulos, SM Altmann, I Kufareva, KE Strathearn, ...
science 317 (5837), 516-519, 2007
Exosomal cell-to-cell transmission of alpha synuclein oligomers
KM Danzer, LR Kranich, WP Ruf, O Cagsal-Getkin, AR Winslow, L Zhu, ...
Molecular neurodegeneration 7, 1-18, 2012
Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy
TL Spires, M Meyer-Luehmann, EA Stern, PJ McLean, J Skoch, ...
Journal of Neuroscience 25 (31), 7278-7287, 2005
Hsp70 reduces α-synuclein aggregation and toxicity
J Klucken, Y Shin, E Masliah, BT Hyman, PJ McLean
Journal of Biological Chemistry 279 (24), 25497-25502, 2004
Formation of toxic oligomeric α-synuclein species in living cells
TF Outeiro, P Putcha, JE Tetzlaff, R Spoelgen, M Koker, F Carvalho, ...
PloS one 3 (4), e1867, 2008
Direct quantification of CSF α-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration
B Mollenhauer, V Cullen, I Kahn, B Krastins, TF Outeiro, I Pepivani, J Ng, ...
Experimental neurology 213 (2), 315-325, 2008
Distinct roles in vivo for the ubiquitin–proteasome system and the autophagy–lysosomal pathway in the degradation of α-synuclein
D Ebrahimi-Fakhari, I Cantuti-Castelvetri, Z Fan, E Rockenstein, ...
Journal of Neuroscience 31 (41), 14508-14520, 2011
Double-blind trial of imipramine in Alzheimer’s disease patients with and without depression
BV Reifler, L Teri, M Raskind, R Veith, R Barnes, E White, P McLean
Am J Psychiatry 146 (1), 45-9, 1989
Targeted overexpression of human α-synuclein triggers microglial activation and an adaptive immune response in a mouse model of Parkinson disease
S Theodore, S Cao, PJ McLean, DG Standaert
Journal of Neuropathology & Experimental Neurology 67 (12), 1149-1158, 2008
TorsinA and heat shock proteins act as molecular chaperones: suppression of α‐synuclein aggregation
PJ McLean, H Kawamata, S Shariff, J Hewett, N Sharma, K Ueda, ...
Journal of neurochemistry 83 (4), 846-854, 2002
The co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates α-synuclein degradation decisions between proteasomal and lysosomal pathways
Y Shin, J Klucken, C Patterson, BT Hyman, PJ McLean
Journal of Biological Chemistry 280 (25), 23727-23734, 2005
α‐Synuclein oligomers and clinical implications for Parkinson disease
LV Kalia, SK Kalia, PJ McLean, AM Lozano, AE Lang
Annals of neurology 73 (2), 155-169, 2013
Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity
KM Danzer, WP Ruf, P Putcha, D Joyner, T Hashimoto, C Glabe, ...
The FASEB journal 25 (1), 326, 2011
Pharmacological promotion of inclusion formation: a therapeutic approach for Huntington’s and Parkinson’s diseases
RA Bodner, TF Outeiro, S Altmann, MM Maxwell, SH Cho, BT Hyman, ...
Proceedings of the National Academy of Sciences 103 (11), 4246-4251, 2006
Membrane association and protein conformation of α-synuclein in intact neurons: effect of Parkinson′ s disease-linked mutations
PJ McLean, H Kawamata, S Ribich, BT Hyman
Journal of Biological Chemistry 275 (12), 8812-8816, 2000
Protein degradation pathways in Parkinson’s disease: curse or blessing
D Ebrahimi-Fakhari, L Wahlster, PJ McLean
Acta neuropathologica 124, 153-172, 2012
Alpha-synuclein and tau: teammates in neurodegeneration?
S Moussaud, DR Jones, EL Moussaud-Lamodière, M Delenclos, OA Ross, ...
Molecular neurodegeneration 9, 1-14, 2014
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