| IFN-γ–related mRNA profile predicts clinical response to PD-1 blockade M Ayers, J Lunceford, M Nebozhyn, E Murphy, A Loboda, DR Kaufman, ... The Journal of clinical investigation 127 (8), 2930-2940, 2017 | 2857 | 2017 |
| Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes R Cristescu, J Lee, M Nebozhyn, KM Kim, JC Ting, SS Wong, J Liu, ... Nature medicine 21 (5), 449-456, 2015 | 1819 | 2015 |
| Pan-tumor genomic biomarkers for PD-1 checkpoint blockade–based immunotherapy R Cristescu, R Mogg, M Ayers, A Albright, E Murphy, J Yearley, X Sher, ... Science 362 (6411), eaar3593, 2018 | 1792 | 2018 |
| Comprehensive molecular characterization of clinical responses to PD-1 inhibition in metastatic gastric cancer ST Kim, R Cristescu, AJ Bass, KM Kim, JI Odegaard, K Kim, XQ Liu, ... Nature medicine 24 (9), 1449-1458, 2018 | 1229 | 2018 |
| Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma Z Kan, H Zheng, X Liu, S Li, TD Barber, Z Gong, H Gao, K Hao, ... Genome research 23 (9), 1422-1433, 2013 | 556 | 2013 |
| Cancer-associated fibroblasts neutralize the anti-tumor effect of CSF1 receptor blockade by inducing PMN-MDSC infiltration of tumors V Kumar, L Donthireddy, D Marvel, T Condamine, F Wang, ... Cancer cell 32 (5), 654-668. e5, 2017 | 539 | 2017 |
| Phase 1 study of the histone deacetylase inhibitor vorinostat (suberoylanilide hydroxamic acid [SAHA]) in patients with advanced leukemias and myelodysplastic syndromes G Garcia-Manero, H Yang, C Bueso-Ramos, A Ferrajoli, J Cortes, ... Blood, The Journal of the American Society of Hematology 111 (3), 1060-1066, 2008 | 529 | 2008 |
| Phase II trial of vorinostat in recurrent glioblastoma multiforme: a north central cancer treatment group study E Galanis, KA Jaeckle, MJ Maurer, JM Reid, MM Ames, JS Hardwick, ... Journal of clinical oncology 27 (12), 2052, 2009 | 401 | 2009 |
| Analysis of genomic targets reveals complex functions of MYC JH Patel, AP Loboda, MK Showe, LC Showe, SB McMahon Nature Reviews Cancer 4 (7), 562-568, 2004 | 380 | 2004 |
| Phase I pharmacologic and pharmacodynamic study of the gamma secretase (Notch) inhibitor MK-0752 in adult patients with advanced solid tumors I Krop, T Demuth, T Guthrie, PY Wen, WP Mason, P Chinnaiyan, ... Journal of clinical oncology 30 (19), 2307-2313, 2012 | 343 | 2012 |
| Unique ectopic lymph node-like structures present in human primary colorectal carcinoma are identified by immune gene array profiling D Coppola, M Nebozhyn, F Khalil, H Dai, T Yeatman, A Loboda, JJ Mulé The American journal of pathology 179 (1), 37-45, 2011 | 323 | 2011 |
| EMT is the dominant program in human colon cancer A Loboda, MV Nebozhyn, JW Watters, CA Buser, PM Shaw, PS Huang, ... BMC medical genomics 4, 1-10, 2011 | 320 | 2011 |
| Functional genomics identifies therapeutic targets for MYC-driven cancer M Toyoshima, HL Howie, M Imakura, RM Walsh, JE Annis, AN Chang, ... Proceedings of the National Academy of Sciences 109 (24), 9545-9550, 2012 | 292 | 2012 |
| An unbiased oncology compound screen to identify novel combination strategies J O'Neil, Y Benita, I Feldman, M Chenard, B Roberts, Y Liu, J Li, A Kral, ... Molecular cancer therapeutics 15 (6), 1155-1162, 2016 | 263 | 2016 |
| Transcriptional architecture of the primate neocortex A Bernard, LS Lubbers, KQ Tanis, R Luo, AA Podtelezhnikov, EM Finney, ... Neuron 73 (6), 1083-1099, 2012 | 246 | 2012 |
| Association of response to programmed death receptor 1 (PD-1) blockade with pembrolizumab (MK-3475) with an interferon-inflammatory immune gene signature. A Ribas, C Robert, FS Hodi, JD Wolchok, AM Joshua, WJ Hwu, JS Weber, ... Journal of Clinical Oncology 33 (15_suppl), 3001-3001, 2015 | 243 | 2015 |
| Classification and prediction of survival in patients with the leukemic phase of cutaneous T cell lymphoma L Kari, A Loboda, M Nebozhyn, AH Rook, EC Vonderheid, C Nichols, ... The Journal of experimental medicine 197 (11), 1477-1488, 2003 | 236 | 2003 |
| A multigene mutation classification of 468 colorectal cancers reveals a prognostic role for APC MJ Schell, M Yang, JK Teer, FY Lo, A Madan, D Coppola, ANA Monteiro, ... Nature communications 7 (1), 11743, 2016 | 208 | 2016 |
| Comparative expression pathway analysis of human and canine mammary tumors P Uva, L Aurisicchio, J Watters, A Loboda, A Kulkarni, J Castle, ... BMC genomics 10, 1-20, 2009 | 201 | 2009 |
| Constitutive activation of signal transducers and activators of transcription predicts vorinostat resistance in cutaneous T-cell lymphoma VR Fantin, A Loboda, CP Paweletz, RC Hendrickson, JW Pierce, JA Roth, ... Cancer research 68 (10), 3785-3794, 2008 | 199 | 2008 |
Razvan CristescuDistinguished Scientist, MerckVerified email at merck.com
