| Is there new hope for therapeutic matrix metalloproteinase inhibition? RE Vandenbroucke, C Libert Nature reviews Drug discovery 13 (12), 904-927, 2014 | 768 | 2014 |
| The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls D Vercauteren, RE Vandenbroucke, AT Jones, J Rejman, J Demeester, ... Molecular Therapy 18 (3), 561-569, 2010 | 761 | 2010 |
| A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment H Van Hove, L Martens, I Scheyltjens, K De Vlaminck, AR Pombo Antunes, ... Nature neuroscience 22 (6), 1021-1035, 2019 | 601 | 2019 |
| Nanobodies as therapeutics: big opportunities for small antibodies S Steeland, RE Vandenbroucke, C Libert Drug discovery today 21 (7), 1076-1113, 2016 | 404 | 2016 |
| The internalization route resulting in successful gene expression depends on both cell line and polyethylenimine polyplex type K Von Gersdorff, NN Sanders, R Vandenbroucke, SC De Smedt, ... Molecular therapy 14 (5), 745-753, 2006 | 375 | 2006 |
| Intracellularly degradable polyelectrolyte microcapsules BG De Geest, RE Vandenbroucke, AM Guenther, GB Sukhorukov, ... Advanced materials 18 (8), 1005-1009, 2006 | 369 | 2006 |
| Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier SE Storck, S Meister, J Nahrath, JN Meißner, N Schubert, A Di Spiezio, ... The Journal of clinical investigation 126 (1), 123-136, 2016 | 350 | 2016 |
| Identification of a novel mechanism of blood–brain communication during peripheral inflammation via choroid plexus‐derived extracellular vesicles S Balusu, E Van Wonterghem, R De Rycke, K Raemdonck, S Stremersch, ... EMBO molecular medicine 8 (10), 1162-1183, 2016 | 305 | 2016 |
| Single-cell profiling of myeloid cells in glioblastoma across species and disease stage reveals macrophage competition and specialization AR Pombo Antunes, I Scheyltjens, F Lodi, J Messiaen, A Antoranz, ... Nature neuroscience 24 (4), 595-610, 2021 | 265 | 2021 |
| Ultrasound-responsive polymer-coated microbubbles that bind and protect DNA I Lentacker, BG De Geest, RE Vandenbroucke, L Peeters, J Demeester, ... Langmuir 22 (17), 7273-7278, 2006 | 210 | 2006 |
| Friends or foes: matrix metalloproteinases and their multifaceted roles in neurodegenerative diseases M Brkic, S Balusu, C Libert, RE Vandenbroucke Mediators of inflammation 2015, 2015 | 200 | 2015 |
| An inflammatory triangle in psoriasis: TNF, type I IFNs and IL-17 L Grine, L Dejager, C Libert, RE Vandenbroucke Cytokine & growth factor reviews 26 (1), 25-33, 2015 | 200 | 2015 |
| Biological membranes in EV biogenesis, stability, uptake, and cargo transfer: an ISEV position paper arising from the ISEV membranes and EVs workshop AE Russell, A Sneider, KW Witwer, P Bergese, SN Bhattacharyya, ... Journal of Extracellular Vesicles 8 (1), 1684862, 2019 | 199 | 2019 |
| Passenger mutations confound interpretation of all genetically modified congenic mice TV Berghe, P Hulpiau, L Martens, RE Vandenbroucke, ... Immunity 43 (1), 200-209, 2015 | 183 | 2015 |
| Treatment of TNF mediated diseases by selective inhibition of soluble TNF or TNFR1 F Van Hauwermeiren, RE Vandenbroucke, C Libert Cytokine & growth factor reviews 22 (5-6), 311-319, 2011 | 177 | 2011 |
| Amyloid β oligomers disrupt blood–CSF barrier integrity by activating matrix metalloproteinases M Brkic, S Balusu, E Van Wonterghem, N Gorlé, I Benilova, A Kremer, ... Journal of Neuroscience 35 (37), 12766-12778, 2015 | 170 | 2015 |
| The power of imaging to understand extracellular vesicle biology in vivo FJ Verweij, L Balaj, CM Boulanger, DRF Carter, EB Compeer, G D’angelo, ... Nature methods 18 (9), 1013-1026, 2021 | 151 | 2021 |
| Ultrasound assisted siRNA delivery using PEG-siPlex loaded microbubbles RE Vandenbroucke, I Lentacker, J Demeester, SC De Smedt, ... Journal of controlled release 126 (3), 265-273, 2008 | 147 | 2008 |
| Biodegradable dextran nanogels for RNA interference: focusing on endosomal escape and intracellular siRNA delivery K Raemdonck, B Naeye, K Buyens, RE Vandenbroucke, A Høgset, ... Advanced Functional Materials 19 (9), 1406-1415, 2009 | 145 | 2009 |
| Into rather unexplored terrain—Transcellular transport across the blood–brain barrier M De Bock, V Van Haver, RE Vandenbroucke, E Decrock, N Wang, ... Glia 64 (7), 1097-1123, 2016 | 141 | 2016 |
Sophie SteelandPost-doctoral researcherVerified email at irc.ugent.be
