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han chong toh
han chong toh
Deputy CEO, National Cancer Centre Singapore, Duke-NUS Medical School
Geverifieerd e-mailadres voor singhealth.com.sg
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A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets
N Deng, LK Goh, H Wang, K Das, J Tao, IB Tan, S Zhang, M Lee, J Wu, ...
Gut 61 (5), 673-684, 2012
7222012
Revisiting the role of CD4+ T cells in cancer immunotherapy—new insights into old paradigms
RE Tay, EK Richardson, HC Toh
Cancer gene therapy 28 (1), 5-17, 2021
7162021
Linifanib versus Sorafenib in patients with advanced hepatocellular carcinoma: results of a randomized phase III trial
C Cainap, S Qin, WT Huang, IJ Chung, H Pan, Y Cheng, M Kudo, ...
Journal of Clinical Oncology 33 (2), 172-179, 2015
6682015
Interaction between tumour-infiltrating B cells and T cells controls the progression of hepatocellular carcinoma
M Garnelo, A Tan, Z Her, J Yeong, CJ Lim, J Chen, KH Lim, A Weber, ...
Gut 66 (2), 342-351, 2017
4332017
Intrinsic subtypes of gastric cancer, based on gene expression pattern, predict survival and respond differently to chemotherapy
IB Tan, T Ivanova, KH Lim, CW Ong, N Deng, J Lee, SH Tan, J Wu, ...
Gastroenterology 141 (2), 476-485. e11, 2011
4222011
Chemokine-driven lymphocyte infiltration: an early intratumoural event determining long-term survival in resectable hepatocellular carcinoma
V Chew, J Chen, D Lee, E Loh, J Lee, KH Lim, A Weber, K Slankamenac, ...
Gut 61 (3), 427-438, 2012
3872012
Inflammatory tumour microenvironment is associated with superior survival in hepatocellular carcinoma patients
V Chew, C Tow, M Teo, HL Wong, J Chan, A Gehring, M Loh, A Bolze, ...
Journal of hepatology 52 (3), 370-379, 2010
3052010
Multidimensional analyses reveal distinct immune microenvironment in hepatitis B virus-related hepatocellular carcinoma
CJ Lim, YH Lee, L Pan, L Lai, C Chua, M Wasser, TKH Lim, J Yeong, ...
Gut 68 (5), 916-927, 2019
2972019
Molecular correlates of clinical response and resistance to atezolizumab in combination with bevacizumab in advanced hepatocellular carcinoma
AX Zhu, AR Abbas, MR de Galarreta, Y Guan, S Lu, H Koeppen, W Zhang, ...
Nature medicine 28 (8), 1599-1611, 2022
2962022
Intentional induction of mixed chimerism and achievement of antitumor responses after nonmyeloablative conditioning therapy and HLA-matched donor bone marrow transplantation …
TR Spitzer, S McAfee, R Sackstein, C Colby, HC Toh, P Multani, ...
Biology of Blood and Marrow Transplantation 6 (3), 309-320, 2000
2932000
Adoptive T-cell transfer and chemotherapy in the first-line treatment of metastatic and/or locally recurrent nasopharyngeal carcinoma
WK Chia, M Teo, WW Wang, B Lee, SF Ang, WM Tai, CL Chee, J Ng, ...
Molecular Therapy 22 (1), 132-139, 2014
2912014
Human bone marrow-derived mesenchymal stem cells suppress human glioma growth through inhibition of angiogenesis
IAW Ho, HC Toh, WH Ng, YL Teo, CM Guo, KM Hui, PYP Lam
Stem cells 31 (1), 146-155, 2013
2872013
Epstein-Barr virus-associated smooth muscle tumors are distinctive mesenchymal tumors reflecting multiple infection events: a clinicopathologic and molecular analysis of 29 …
AT Deyrup, VK Lee, CE Hill, W Cheuk, HC Toh, S Kesavan, EW Chan, ...
The American journal of surgical pathology 30 (1), 75-82, 2006
2592006
Delineation of an immunosuppressive gradient in hepatocellular carcinoma using high-dimensional proteomic and transcriptomic analyses
V Chew, L Lai, L Pan, CJ Lim, J Li, R Ong, C Chua, JY Leong, KH Lim, ...
Proceedings of the National Academy of Sciences 114 (29), E5900-E5909, 2017
2242017
Immune microenvironment in tumor progression: characteristics and challenges for therapy
V Chew, HC Toh, JP Abastado
Journal of oncology 2012 (1), 608406, 2012
2202012
Loss of BCAA catabolism during carcinogenesis enhances mTORC1 activity and promotes tumor development and progression
RE Ericksen, SL Lim, E McDonnell, WH Shuen, M Vadiveloo, PJ White, ...
Cell metabolism 29 (5), 1151-1165. e6, 2019
1982019
Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy
Y Zhao, TWH Shuen, TB Toh, XY Chan, M Liu, SY Tan, Y Fan, H Yang, ...
Gut 67 (10), 1845-1854, 2018
1832018
Targeting dendritic cells to enhance DNA vaccine potency
Z You, X Huang, J Hester, HC Toh, SY Chen
Cancer research 61 (9), 3704-3711, 2001
1812001
RAD001 (everolimus) inhibits tumour growth in xenograft models of human hepatocellular carcinoma
H Huynh, KH Pierce Chow, KC Soo, HC Toh, SP Choo, KF Foo, D Poon, ...
Journal of cellular and molecular medicine 13 (7), 1371-1380, 2009
1672009
Efficacy and tolerability of bevacizumab plus capecitabine as first-line therapy in patients with advanced hepatocellular carcinoma
CH Hsu, TS Yang, C Hsu, HC Toh, RJ Epstein, LT Hsiao, PJ Chen, ZZ Lin, ...
British Journal of Cancer 102 (6), 981-986, 2010
1622010
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