Barbara Leggett
Barbara Leggett
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CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer
DJ Weisenberger, KD Siegmund, M Campan, J Young, TI Long, ...
Nature genetics 38 (7), 787-793, 2006
Role of the serrated pathway in colorectal cancer pathogenesis
B Leggett, V Whitehall
Gastroenterology 138 (6), 2088-2100, 2010
Immunohistochemistry versus microsatellite instability testing in phenotyping colorectal tumors
NM Lindor, LJ Burgart, O Leontovich, RM Goldberg, JM Cunningham, ...
Journal of clinical oncology 20 (4), 1043-1048, 2002
BRAF mutation is associated with DNA methylation in serrated polyps and cancers of the colorectum
T Kambara, LA Simms, VLJ Whitehall, KJ Spring, CVA Wynter, MD Walsh, ...
Gut 53 (8), 1137-1144, 2004
Emerging concepts in colorectal neoplasia
JR Jass, VLJ Whitehall, J Young, BA Leggett
Gastroenterology 123 (3), 862-876, 2002
High prevalence of sessile serrated adenomas with BRAF mutations: a prospective study of patients undergoing colonoscopy
KJ Spring, ZZ Zhao, R Karamatic, MD Walsh, VLJ Whitehall, T Pike, ...
Gastroenterology 131 (5), 1400-1407, 2006
Morphology of sporadic colorectal cancer with DNA replication errors
JR Jass, KA Do, LA Simms, H Iino, C Wynter, SP Pillay, J Searle, ...
Gut 42 (5), 673-679, 1998
Microsatellite instability in the insulin–like growth factor II receptor gene in gastrointestinal tumours
RF Souza, R Appel, J Yin, S Wang, KN Smolinski, JM Abraham, TT Zou, ...
Nature genetics 14 (3), 255-257, 1996
Features of colorectal cancers with high-level microsatellite instability occurring in familial and sporadic settings: parallel pathways of tumorigenesis
J Young, LA Simms, KG Biden, C Wynter, V Whitehall, R Karamatic, ...
The American journal of pathology 159 (6), 2107-2116, 2001
The serrated pathway to colorectal carcinoma: current concepts and challenges
M Bettington, N Walker, A Clouston, I Brown, B Leggett, V Whitehall
Histopathology 62 (3), 367-386, 2013
Whole-genome landscape of pancreatic neuroendocrine tumours
A Scarpa, DK Chang, K Nones, V Corbo, AM Patch, P Bailey, RT Lawlor, ...
Nature 543 (7643), 65-71, 2017
DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer?
H Iino, JR Jass, LA Simms, J Young, B Leggett, Y Ajioka, H Watanabe
Journal of Clinical Pathology 52 (1), 5-9, 1999
Risks of Lynch Syndrome Cancers for MSH6 Mutation Carriers
L Baglietto, NM Lindor, JG Dowty, DM White, A Wagner, ...
Journal of the National Cancer Institute 102 (3), 193-201, 2010
Safe procedure in endoscopic submucosal dissection for colorectal tumors focused on preventing complications
N Yoshida, N Yagi, Y Naito, T Yoshikawa
World Journal of Gastroenterology: WJG 16 (14), 1688, 2010
Methylation of O–6-methylguanine DNA methyltransferase characterizes a subset of colorectal cancer with low-level DNA microsatellite instability
VLJ Whitehall, MD Walsh, J Young, BA Leggett, JR Jass
Cancer research 61 (3), 827-830, 2001
Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways.
JR Jass, KG Biden, MC Cummings, LA Simms, M Walsh, E Schoch, ...
Journal of clinical pathology 52 (6), 455-460, 1999
Neoplastic progression occurs through mutator pathways in hyperplastic polyposis of the colorectum
JR Jass, H Iino, A Ruszkiewicz, D Painter, MJ Solomon, DJ Koorey, ...
Gut 47 (1), 43-49, 2000
Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes
XP Zhou, K Woodford-Richens, R Lehtonen, K Kurose, M Aldred, ...
The American Journal of Human Genetics 69 (4), 704-711, 2001
Colorectal cancer with mutation in BRAF, KRAS, and wild-type with respect to both oncogenes showing different patterns of DNA methylation
T Nagasaka, H Sasamoto, K Notohara, HM Cullings, M Takeda, K Kimura, ...
Journal of Clinical Oncology 22 (22), 4584-4594, 2004
Metachronous colorectal cancer risk for mismatch repair gene mutation carriers: the advantage of more extensive colon surgery
S Parry, AK Win, B Parry, FA Macrae, LC Gurrin, JM Church, JA Baron, ...
Gut 60 (7), 950-957, 2011
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