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Kim A. Staats
Kim A. Staats
Director of Rare Disease Drug Development, INmune Bio
Geverifieerd e-mailadres voor inmunebio.com
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Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis
W Van Rheenen, A Shatunov, AM Dekker, RL McLaughlin, FP Diekstra, ...
Nature genetics 48 (9), 1043-1048, 2016
5842016
Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons
Y Shi, S Lin, KA Staats, Y Li, WH Chang, ST Hung, E Hendricks, ...
Nature medicine 24 (3), 313-325, 2018
5272018
EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans
A Van Hoecke, L Schoonaert, R Lemmens, M Timmers, KA Staats, ...
Nature medicine 18 (9), 1418-1422, 2012
3442012
Oligodendrocyte dysfunction in the pathogenesis of amyotrophic lateral sclerosis
T Philips, A Bento-Abreu, A Nonneman, W Haeck, K Staats, V Geelen, ...
Brain 136 (2), 471-482, 2013
2742013
The microRNA-29 family dictates the balance between homeostatic and pathological glucose handling in diabetes and obesity
J Dooley, JE Garcia-Perez, J Sreenivasan, SM Schlenner, ...
Diabetes 65 (1), 53-61, 2016
1502016
Rapamycin increases survival in ALS mice lacking mature lymphocytes
KA Staats, S Hernandez, S Schönefeldt, A Bento-Abreu, J Dooley, ...
Molecular neurodegeneration 8, 1-5, 2013
712013
Elongator subunit 3 (ELP3) modifies ALS through tRNA modification
A Bento-Abreu, G Jager, B Swinnen, L Rué, S Hendrickx, A Jones, ...
Human molecular genetics 27 (7), 1276-1289, 2018
662018
ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD
S Moore, E Alsop, I Lorenzini, A Starr, BE Rabichow, E Mendez, JL Levy, ...
Acta neuropathologica 138, 49-65, 2019
622019
Olmsted syndrome: exploration of the immunological phenotype
D Danso-Abeam, J Zhang, J Dooley, KA Staats, L Van Eyck, ...
Orphanet journal of rare diseases 8, 1-8, 2013
582013
Astrocytes in amyotrophic lateral sclerosis: direct effects on motor neuron survival
KA Staats, L Van Den Bosch
Journal of biological physics 35 (4), 337-346, 2009
582009
Blood-based biomarkers of inflammation in amyotrophic lateral sclerosis
KA Staats, DR Borchelt, MG Tansey, J Wymer
Molecular Neurodegeneration 17 (1), 11, 2022
432022
The multifaceted role of kinases in amyotrophic lateral sclerosis: genetic, pathological and therapeutic implications
W Guo, T Vandoorne, J Steyaert, KA Staats, L Van Den Bosch
Brain 143 (6), 1651-1673, 2020
432020
Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons
Y Shi, ST Hung, G Rocha, S Lin, GR Linares, KA Staats, C Seah, Y Wang, ...
JCI insight 4 (15), 2019
432019
Genome-wide burden of deleterious coding variants increased in schizophrenia
DYJ Loohuis LM, Vorstman JA, Ori AP, Staats KA, Wang T, Richards AL ...
Nature Communications 6 (7501), 2015
312015
Dupuytren's disease susceptibility gene, EPDR1, is involved in myofibroblast contractility.
KA Staats, T Wu, BS Gan, DB O'Gorman, RA Ophoff
Journal of Dermatological Sciences 83 (2), 131-137, 2016
282016
PARALS Registry; SLALOM Group; SLAP Registry; FALS Sequencing Consortium; SLAGEN Consortium; NNIPPS Study Group. Genome-wide association analyses identify new risk variants and …
W van Rheenen, A Shatunov, AM Dekker, RL McLaughlin, FP Diekstra, ...
Nat Genet 48 (9), 1043-1048, 2016
282016
Aire mediates thymic expression and tolerance of pancreatic antigens via an unconventional transcriptional mechanism
D Danso‐Abeam, KA Staats, D Franckaert, L Van Den Bosch, A Liston, ...
European journal of immunology 43 (1), 75-84, 2013
252013
Genetic ablation of IP3 receptor 2 increases cytokines and decreases survival of SOD1G93A mice
KA Staats, S Humblet-Baron, A Bento-Abreu, W Scheveneels, A Nikolaou, ...
Human molecular genetics 25 (16), 3491-3499, 2016
242016
Beta-2 microglobulin is important for disease progression in a murine model for amyotrophic lateral sclerosis
KA Staats, S Schönefeldt, M Van Rillaer, A Van Hoecke, P Van Damme, ...
Frontiers in Cellular Neuroscience 7, 249, 2013
242013
Loss of T cell microRNA provides systemic protection against autoimmune pathology in mice
L Tian, G De Hertogh, M Fedeli, KA Staats, S Schonefeldt, ...
Journal of autoimmunity 38 (1), 39-48, 2012
232012
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Artikelen 1–20