| Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis K Wouters, PJ van Gorp, V Bieghs, MJ Gijbels, H Duimel, D Lütjohann, ... Hepatology 48 (2), 474-486, 2008 | 554 | 2008 |
| Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates R Shiri-Sverdlov, K Wouters, PJ van Gorp, MJ Gijbels, B Noel, L Buffat, ... Journal of hepatology 44 (4), 732-741, 2006 | 219 | 2006 |
| Understanding hyperlipidemia and atherosclerosis: lessons from genetically modified apoe and ldlr mice K Wouters, R Shiri-Sverdlov, PJ van Gorp, M van Bilsen, MH Hofker Clinical Chemistry and Laboratory Medicine (CCLM) 43 (5), 470-479, 2005 | 204 | 2005 |
| LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease V Bieghs, PJ Van Gorp, K Wouters, T Hendrikx, MJ Gijbels, M van Bilsen, ... PloS one 7 (1), e30668, 2012 | 197 | 2012 |
| Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice V Bieghs, K Wouters, PJ Van Gorp, MJJ Gijbels, MPJ De Winther, ... Gastroenterology 138 (7), 2477-2486. e3, 2010 | 184 | 2010 |
| Bone marrow–specific deficiency of nuclear receptor Nur77 enhances atherosclerosis AAJ Hamers, M Vos, F Rassam, G Marinković, K Kurakula, PJ Van Gorp, ... Circulation research 110 (3), 428-438, 2012 | 180 | 2012 |
| Hyperlipidemia and cutaneous abnormalities in transgenic mice overexpressing human apolipoprotein C1. MC Jong, MJ Gijbels, VE Dahlmans, PJ Gorp, SJ Koopman, M Ponec, ... The Journal of clinical investigation 101 (1), 145-152, 1998 | 173 | 1998 |
| In the absence of the low density lipoprotein receptor, human apolipoprotein C1 overexpression in transgenic mice inhibits the hepatic uptake of very low density lipoproteins … MC Jong, VE Dahlmans, PJ Van Gorp, KW van Dijk, ML Breuer, ... The Journal of clinical investigation 98 (10), 2259-2267, 1996 | 140 | 1996 |
| Internalization of modified lipids by CD36 and SR-A leads to hepatic inflammation and lysosomal cholesterol storage in Kupffer cells V Bieghs, F Verheyen, PJ van Gorp, T Hendrikx, K Wouters, D Lütjohann, ... PloS one 7 (3), e34378, 2012 | 131 | 2012 |
| Intrahepatic cholesterol influences progression, inhibition and reversal of non-alcoholic steatohepatitis in hyperlipidemic mice K Wouters, M van Bilsen, PJ van Gorp, V Bieghs, D Lütjohann, A Kerksiek, ... FEBS letters 584 (5), 1001-1005, 2010 | 117 | 2010 |
| Specific immunization strategies against oxidized low‐density lipoprotein: a novel way to reduce nonalcoholic steatohepatitis in mice V Bieghs, PJ van Gorp, SMA Walenbergh, MJ Gijbels, F Verheyen, ... Hepatology 56 (3), 894-903, 2012 | 116 | 2012 |
| Macrophage-specific overexpression of group IIa sPLA2 increases atherosclerosis and enhances collagen deposition SAI Ghesquiere, MJJ Gijbels, M Anthonsen, PJJ van Gorp, I van der Made, ... Journal of lipid research 46 (2), 201-210, 2005 | 114 | 2005 |
| Scavenger receptor deficiency leads to more complex atherosclerotic lesions in APOE3Leiden transgenic mice MPJ de Winther, MJJ Gijbels, KW van Dijk, PJJ van Gorp, H Suzuki, ... Atherosclerosis 144 (2), 315-321, 1999 | 102 | 1999 |
| Trapping of oxidized LDL in lysosomes of K upffer cells is a trigger for hepatic inflammation V Bieghs, SMA Walenbergh, T Hendrikx, PJ van Gorp, F Verheyen, ... Liver International 33 (7), 1056-1061, 2013 | 101 | 2013 |
| The cholesterol derivative 27-hydroxycholesterol reduces steatohepatitis in mice V Bieghs, T Hendrikx, PJ van Gorp, F Verheyen, YD Guichot, ... Gastroenterology 144 (1), 167-178. e1, 2013 | 101 | 2013 |
| Xanthine oxidase inhibitor tungsten prevents the development of atherosclerosis in ApoE knockout mice fed a Western-type diet K Schröder, C Vecchione, O Jung, JG Schreiber, R Shiri-Sverdlov, ... Free Radical Biology and Medicine 41 (9), 1353-1360, 2006 | 99 | 2006 |
| Reprogramming macrophages to an anti-inflammatory phenotype by helminth antigens reduces murine atherosclerosis IMJ Wolfs, JL Stoger, P Goossens, C Pottgens, MJJ Gijbels, E Wijnands, ... Faseb Journal 28 (1), 288-299, 2014 | 97 | 2014 |
| Bone marrow‐specific caspase‐1/11 deficiency inhibits atherosclerosis development in Ldlr−/− mice T Hendrikx, MLJ Jeurissen, PJ van Gorp, MJ Gijbels, SMA Walenbergh, ... The FEBS journal 282 (12), 2327-2338, 2015 | 72 | 2015 |
| Both lipolysis and hepatic uptake of VLDL are impaired in transgenic mice coexpressing human apolipoprotein E* 3Leiden and human apolipoprotein C1 MC Jong, VEH Dahlmans, PJJ van Gorp, ML Breuer, MJTM Mol, ... Arteriosclerosis, thrombosis, and vascular biology 16 (8), 934-940, 1996 | 63 | 1996 |
| Protective role of plant sterol and stanol esters in liver inflammation: insights from mice and humans J Plat, T Hendrikx, V Bieghs, MLJ Jeurissen, SMA Walenbergh, ... PloS one 9 (10), e110758, 2014 | 61 | 2014 |
Marten HofkerProfessor of Molecular Genetics, UMCG, Groningen University, The NetherlandsGeverifieerd e-mailadres voor umcg.nl
