Influence of threonine metabolism on S-adenosylmethionine and histone methylation N Shyh-Chang, JW Locasale, CA Lyssiotis, Y Zheng, RY Teo, ... Science 339 (6116), 222-226, 2013 | 664 | 2013 |
Post-transcriptional regulation of de novo lipogenesis by mTORC1-S6K1-SRPK2 signaling G Lee, Y Zheng, S Cho, C Jang, C England, JM Dempsey, Y Yu, X Liu, ... Cell 171 (7), 1545-1558. e18, 2017 | 195 | 2017 |
Lipoxygenases Mediate the Effect of Essential Fatty Acid in Skin Barrier Formation: A PROPOSED ROLE IN RELEASING OMEGA-HYDROXYCERAMIDE FOR CONSTRUCTION OF THE CORNEOCYTE LIPID … Y Zheng, H Yin, WE Boeglin, PM Elias, D Crumrine, DR Beier, AR Brash Journal of Biological Chemistry 286 (27), 24046-24056, 2011 | 187 | 2011 |
Toward a better understanding of folate metabolism in health and disease Y Zheng, LC Cantley Journal of Experimental Medicine 216 (2), 253-266, 2019 | 153 | 2019 |
PARK2 depletion connects energy and oxidative stress to PI3K/Akt activation via PTEN S-nitrosylation A Gupta, S Anjomani-Virmouni, N Koundouros, M Dimitriadi, ... Molecular cell 65 (6), 999-1013. e7, 2017 | 126 | 2017 |
The importance of the lipoxygenase-hepoxilin pathway in the mammalian epidermal barrier A Muñoz-Garcia, CP Thomas, DS Keeney, Y Zheng, AR Brash Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014 | 124 | 2014 |
Mitochondrial one-carbon pathway supports cytosolic folate integrity in cancer cells Y Zheng, TY Lin, G Lee, MN Paddock, J Momb, Z Cheng, Q Li, DL Fei, ... Cell 175 (6), 1546-1560. e17, 2018 | 89 | 2018 |
The lipid kinase PI5P4Kβ is an intracellular GTP sensor for metabolism and tumorigenesis K Sumita, YH Lo, K Takeuchi, M Senda, S Kofuji, Y Ikeda, J Terakawa, ... Molecular cell 61 (2), 187-198, 2016 | 69 | 2016 |
A 49-kDa mini-lipoxygenase from Anabaena sp. PCC 7120 retains catalytically complete functionality Y Zheng, WE Boeglin, C Schneider, AR Brash Journal of biological chemistry 283 (8), 5138-5147, 2008 | 66 | 2008 |
On the role of molecular oxygen in lipoxygenase activation: comparison and contrast of epidermal lipoxygenase-3 with soybean lipoxygenase-1 Y Zheng, AR Brash Journal of biological chemistry 285 (51), 39876-39887, 2010 | 55 | 2010 |
Evidence for an ionic intermediate in the transformation of fatty acid hydroperoxide by a catalase-related allene oxide synthase from the cyanobacterium Acaryochloris marina B Gao, WE Boeglin, Y Zheng, C Schneider, AR Brash Journal of biological chemistry 284 (33), 22087-22098, 2009 | 51 | 2009 |
Enantiomeric separation of hydroxy and hydroperoxy eicosanoids by chiral column chromatography C Schneider, Z Yu, WE Boeglin, Y Zheng, AR Brash Methods in enzymology 433, 145-157, 2007 | 51 | 2007 |
Human pluripotent stem cells decouple respiration from energy production N Shyh‐Chang, Y Zheng, JW Locasale, LC Cantley The EMBO journal 30 (24), 4851-4852, 2011 | 49 | 2011 |
Investigation of substrate binding and product stereochemistry issues in two linoleate 9-lipoxygenases WE Boeglin, A Itoh, Y Zheng, G Coffa, GA Howe, AR Brash Lipids 43, 979-987, 2008 | 43 | 2008 |
Dioxygenase activity of epidermal lipoxygenase-3 unveiled: typical and atypical features of its catalytic activity with natural and synthetic polyunsaturated fatty acids Y Zheng, AR Brash Journal of biological chemistry 285 (51), 39866-39875, 2010 | 42 | 2010 |
Regulation of folate and methionine metabolism by multisite phosphorylation of human methylenetetrahydrofolate reductase Y Zheng, S Ramsamooj, Q Li, JL Johnson, TM Yaron, K Sharra, ... Scientific reports 9 (1), 4190, 2019 | 26 | 2019 |
Formation of a cyclopropyl epoxide via a leukotriene A synthase-related pathway in an anaerobic reaction of soybean lipoxygenase-1 with 15S-hydroperoxyeicosatetraenoic acid … Y Zheng, AR Brash Journal of biological chemistry 285 (18), 13427-13436, 2010 | 20 | 2010 |
Suppression of nuclear GSK3 signaling promotes serine/one-carbon metabolism and confers metabolic vulnerability in lung cancer cells L He, J Endress, S Cho, Z Li, Y Zheng, JM Asara, J Blenis Science Advances 8 (20), eabm8786, 2022 | 16 | 2022 |
Biosynthesis, isolation, and NMR analysis of leukotriene A epoxides: substrate chirality as a determinant of the cis or trans epoxide configuration [S] J Jin, Y Zheng, WE Boeglin, AR Brash Journal of Lipid Research 54 (3), 754-761, 2013 | 16 | 2013 |
Demonstration of HNE-related Aldehyde Formation via Lipoxygenase-catalyzed Synthesis of a bis-Allylic Dihydroperoxide Intermediate J Jin, Y Zheng, AR Brash Chemical research in toxicology 26 (6), 896-903, 2013 | 4 | 2013 |