| Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity F Weinberg, R Hamanaka, WW Wheaton, S Weinberg, J Joseph, M Lopez, ... Proceedings of the National Academy of Sciences 107 (19), 8788-8793, 2010 | 1788 | 2010 |
| Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio BM Emerling, F Weinberg, C Snyder, Z Burgess, GM Mutlu, B Viollet, ... Free Radical Biology and Medicine 46 (10), 1386-1391, 2009 | 375 | 2009 |
| Reactive oxygen species in the tumor microenvironment: an overview F Weinberg, N Ramnath, D Nagrath Cancers 11 (8), 1191, 2019 | 353 | 2019 |
| Reactive oxygen species-dependent signaling regulates cancer F Weinberg, NS Chandel Cellular and molecular life sciences 66, 3663-3673, 2009 | 327 | 2009 |
| PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a) BM Emerling, F Weinberg, JL Liu, TW Mak, NS Chandel Proceedings of the National Academy of Sciences 105 (7), 2622-2627, 2008 | 249 | 2008 |
| Mitochondrial metabolism and cancer F Weinberg, NS Chandel Annals of the New York Academy of Sciences 1177 (1), 66-73, 2009 | 198 | 2009 |
| A chemical genomics screen highlights the essential role of mitochondria in HIF-1 regulation X Lin, CA David, JB Donnelly, M Michaelides, NS Chandel, X Huang, ... Proceedings of the National Academy of Sciences 105 (1), 174-179, 2008 | 129 | 2008 |
| A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: comparison with Carney complex and … KJ Griffin, LS Kirschner, L Matyakhina, SG Stergiopoulos, ... Journal of medical genetics 41 (12), 923-931, 2004 | 125 | 2004 |
| Large Deletions of the PRKAR1A Gene in Carney Complex A Horvath, I Bossis, C Giatzakis, E Levine, F Weinberg, E Meoli, ... Clinical Cancer Research 14 (2), 388-395, 2008 | 115 | 2008 |
| Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors KJ Griffin, LS Kirschner, L Matyakhina, S Stergiopoulos, ... Cancer Research 64 (24), 8811-8815, 2004 | 107 | 2004 |
| Enzastaurin (LY317615), a protein kinase Cβ inhibitor, inhibits the AKT pathway and induces apoptosis in multiple myeloma cell lines MA Rizvi, K Ghias, KM Davies, C Ma, F Weinberg, HG Munshi, NL Krett, ... Molecular cancer therapeutics 5 (7), 1783-1789, 2006 | 88 | 2006 |
| Generation of human fatty livers using custom-engineered induced pluripotent stem cells with modifiable SIRT1 metabolism AC de l’Hortet, K Takeishi, J Guzman-Lepe, K Morita, A Achreja, ... Cell metabolism 30 (2), 385-401. e9, 2019 | 75 | 2019 |
| Protein kinase A effects of an expressed PRKAR1A mutation associated with aggressive tumors E Meoli, I Bossis, L Cazabat, M Mavrakis, A Horvath, S Stergiopoulos, ... Cancer research 68 (9), 3133-3141, 2008 | 75 | 2008 |
| Hyperoxia-induced premature senescence requires p53 and pRb, but not mitochondrial matrix ROS TA Klimova, EL Bell, EH Shroff, FD Weinberg, CM Snyder, GP Dimri, ... The FASEB Journal 23 (3), 783, 2009 | 70 | 2009 |
| Insulin augments GnRH-stimulated LHβ gene expression by Egr-1 C Buggs, F Weinberg, E Kim, A Wolfe, S Radovick, F Wondisford Molecular and cellular endocrinology 249 (1-2), 99-106, 2006 | 47 | 2006 |
| Natural allelic variations in glutathione peroxidase-1 affect its subcellular localization and function S Bera, F Weinberg, DN Ekoue, K Ansenberger-Fricano, M Mao, ... Cancer research 74 (18), 5118-5126, 2014 | 36 | 2014 |
| Cyclin-dependent kinase inhibitors for the treatment of lung cancer A Qin, HG Reddy, FD Weinberg, GP Kalemkerian Expert Opinion on Pharmacotherapy 21 (8), 941-952, 2020 | 25 | 2020 |
| Synthetic lethality: a step forward for personalized medicine in cancer H Jariyal, F Weinberg, A Achreja, D Nagarath, A Srivastava Drug Discovery Today 25 (2), 305-320, 2020 | 20 | 2020 |
| Combination pembrolizumab plus chemotherapy: a new standard of care for patients with advanced non-small-cell lung cancer F Weinberg, S Gadgeel Lung Cancer: Targets and Therapy, 47-56, 2019 | 20 | 2019 |
| A mouse model for Carney complex KJ Griffin, LS Kirschner, L Matyakhina, S Stergiopoulos, ... Endocrine research 30 (4), 903-911, 2004 | 20 | 2004 |
