| A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium SMIII Consortium Nature Biotechnology 32 (9), 903-914, 2014 | 842 | 2014 |
| Next-generation sequencing in the clinic: promises and challenges J Xuan, Y Yu, T Qing, L Guo, L Shi Cancer letters 340 (2), 284-295, 2013 | 406 | 2013 |
| Comparison of RNA-seq and microarray-based models for clinical endpoint prediction W Zhang, Y Yu, F Hertwig, J Thierry-Mieg, W Zhang, D Thierry-Mieg, ... Genome biology 16, 1-12, 2015 | 394 | 2015 |
| Metabolomic profiling to identify potential serum biomarkers for schizophrenia and risperidone action J Xuan, G Pan, Y Qiu, L Yang, M Su, Y Liu, J Chen, G Feng, Y Fang, W Jia, ... Journal of proteome research 10 (12), 5433-5443, 2011 | 162 | 2011 |
| HLA-B*58:01 allele is associated with augmented risk for both mild and severe cutaneous adverse reactions induced by allopurinol in Han Chinese Z Cao, Z Wei, Q Zhu, J Zhang, L Yang, S Qin, L Shao, Y Zhang, J Xuan, ... Pharmacogenomics 13 (10), 1193-1201, 2012 | 127 | 2012 |
| Development of HepG2-derived cells expressing cytochrome P450s for assessing metabolism-associated drug-induced liver toxicity J Xuan, S Chen, B Ning, WH Tolleson, L Guo Chemico-biological interactions 255, 63-73, 2016 | 86 | 2016 |
| Sertraline, an antidepressant, induces apoptosis in hepatic cells through the mitogen-activated protein kinase pathway S Chen, J Xuan, L Wan, H Lin, L Couch, N Mei, VN Dobrovolsky, L Guo Toxicological sciences 137 (2), 404-415, 2014 | 70 | 2014 |
| Ginkgo biloba leaf extract induces DNA damage by inhibiting topoisomerase II activity in human hepatic cells Z Zhang, S Chen, H Mei, J Xuan, X Guo, L Couch, VN Dobrovolsky, L Guo, ... Scientific reports 5 (1), 14633, 2015 | 67 | 2015 |
| Sertraline induces endoplasmic reticulum stress in hepatic cells S Chen, J Xuan, L Couch, A Iyer, Y Wu, QZ Li, L Guo Toxicology 322, 78-88, 2014 | 64 | 2014 |
| HLA-B* 59: 01: a marker for Stevens–Johnson syndrome/toxic epidermal necrolysis caused by methazolamide in Han Chinese F Yang, J Xuan, J Chen, H Zhong, H Luo, P Zhou, X Sun, L He, S Chen, ... The pharmacogenomics journal 16 (1), 83-87, 2016 | 60 | 2016 |
| HLA-B*13:01 is associated with salazosulfapyridine-induced drug rash with eosinophilia and systemic symptoms in Chinese Han population F Yang, B Gu, L Zhang, J Xuan, H Luo, P Zhou, Q Zhu, S Yan, S Chen, ... Pharmacogenomics 15 (11), 1461-1469, 2014 | 53 | 2014 |
| Response of risperidone treatment may be associated with polymorphisms of HTT gene in Chinese schizophrenia patients L Wang, L Yu, G He, J Zhang, AP Zhang, J Du, RQ Tang, XZ Zhao, J Ma, ... Neuroscience letters 414 (1), 1-4, 2007 | 53 | 2007 |
| Pharacogenetic effects of dopamine transporter gene polymorphisms on response to chlorpromazine and clozapine and on extrapyramidal syndrome in schizophrenia M Xu, Q Xing, S Li, Y Zheng, S Wu, R Gao, L Yu, T Guo, Y Yang, J Liu, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 34 (6), 1026-1032, 2010 | 51 | 2010 |
| Effects of the dopamine D3 receptor (DRD3) gene polymorphisms on risperidone response: a pharmacogenetic study J Xuan, X Zhao, G He, L Yu, L Wang, W Tang, X Li, N Gu, G Feng, Q Xing, ... Neuropsychopharmacology 33 (2), 305-311, 2008 | 50 | 2008 |
| Mitochondrial dysfunction induced by leflunomide and its active metabolite J Xuan, Z Ren, T Qing, L Couch, L Shi, WH Tolleson, L Guo Toxicology 396, 33-45, 2018 | 48 | 2018 |
| Endoplasmic reticulum stress and MAPK signaling pathway activation underlie leflunomide-induced toxicity in HepG2 Cells Z Ren, S Chen, T Qing, J Xuan, L Couch, D Yu, B Ning, L Shi, L Guo Toxicology 392, 11-21, 2017 | 48 | 2017 |
| Relationship between response to risperidone, plasma concentrations of risperidone and CYP3A4 polymorphisms in schizophrenia patients J Du, A Zhang, L Wang, J Xuan, L Yu, R Che, X Li, N Gu, Z Lin, G Feng, ... Journal of Psychopharmacology 24 (7), 1115-1120, 2010 | 44 | 2010 |
| Comprehensive analysis of polymorphisms throughout GAD1 gene: a family-based association study in schizophrenia J Du, S Duan, H Wang, W Chen, X Zhao, A Zhang, L Wang, J Xuan, L Yu, ... Journal of neural transmission 115, 513-519, 2008 | 44 | 2008 |
| The role of CYP 3A4 and 1A1 in amiodarone-induced hepatocellular toxicity Q Wu, B Ning, J Xuan, Z Ren, L Guo, MS Bryant Toxicology letters 253, 55-62, 2016 | 40 | 2016 |
| A functional SNP in the 3′‐UTR of TAP2 gene interacts with microRNA hsa‐miR‐1270 to suppress the gene expression B Knox, Y Wang, LJ Rogers, J Xuan, D Yu, H Guan, J Chen, T Shi, B Ning, ... Environmental and molecular mutagenesis 59 (2), 134-143, 2018 | 34 | 2018 |
