| ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data K Wang, M Li, H Hakonarson Nucleic acids research 38 (16), e164-e164, 2010 | 7717 | 2010 |
| Biological, clinical and population relevance of 95 loci for blood lipids TM Teslovich, K Musunuru, AV Smith, AC Edmondson, IM Stylianou, ... Nature 466 (7307), 707-713, 2010 | 3298 | 2010 |
| Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study BF Voight, GM Peloso, M Orho-Melander, R Frikke-Schmidt, M Barbalic, ... The Lancet 380 (9841), 572-580, 2012 | 1942 | 2012 |
| Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk GB Ehret, PB Munroe, KM Rice, M Bochud, AD Johnson, DI Chasman, ... Nature 478 (7367), 103, 2011 | 1867 | 2011 |
| Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease H Schunkert, IR König, S Kathiresan, MP Reilly, TL Assimes, H Holm, ... Nature genetics 43 (4), 333-338, 2011 | 1750 | 2011 |
| PennCNV: an integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data K Wang, M Li, D Hadley, R Liu, J Glessner, SFA Grant, H Hakonarson, ... Genome research 17 (11), 1665-1674, 2007 | 1647 | 2007 |
| Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants S Kathiresan, BF Voight, S Purcell, K Musunuru, D Ardissino, ... Nature genetics 41 (3), 334-341, 2009 | 1121 | 2009 |
| Pathway-based approaches for analysis of genomewide association studies K Wang, M Li, M Bucan The American Journal of Human Genetics 81 (6), 1278-1283, 2007 | 927 | 2007 |
| Analysing biological pathways in genome-wide association studies K Wang, M Li, H Hakonarson Nature Reviews Genetics 11 (12), 843-854, 2010 | 819 | 2010 |
| A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants LG Fritsche, W Igl, JNC Bailey, F Grassmann, S Sengupta, ... Nature genetics 48 (2), 134-143, 2016 | 714 | 2016 |
| Meta-analysis and imputation refines the association of 15q25 with smoking quantity JZ Liu, F Tozzi, DM Waterworth, SG Pillai, P Muglia, L Middleton, ... Nature genetics 42 (5), 436-440, 2010 | 605 | 2010 |
| Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction R Do, NO Stitziel, HH Won, AB Jørgensen, S Duga, PA Merlini, A Kiezun, ... Nature 518 (7537), 102-106, 2015 | 545 | 2015 |
| A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium N Soranzo, TD Spector, M Mangino, B Kühnel, A Rendon, A Teumer, ... Nature genetics 41 (11), 1182-1190, 2009 | 535 | 2009 |
| Widespread RNA and DNA sequence differences in the human transcriptome M Li, IX Wang, Y Li, A Bruzel, AL Richards, JM Toung, VG Cheung science 333 (6038), 53-58, 2011 | 520* | 2011 |
| Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two … MP Reilly, M Li, J He, JF Ferguson, IM Stylianou, NN Mehta, MS Burnett, ... The Lancet 377 (9763), 383-392, 2011 | 478 | 2011 |
| Strong association of the Y402H variant in complement factor H at 1q32 with susceptibility to age-related macular degeneration S Zareparsi, KEH Branham, M Li, S Shah, RJ Klein, J Ott, J Hoh, ... The American Journal of Human Genetics 77 (1), 149-153, 2005 | 433 | 2005 |
| Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies BJ Keating, S Tischfield, SS Murray, T Bhangale, TS Price, JT Glessner, ... PloS one 3 (10), e3583, 2008 | 427 | 2008 |
| Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes M Bucan, BS Abrahams, K Wang, JT Glessner, EI Herman, LI Sonnenblick, ... PLoS Genet 5 (6), e1000536, 2009 | 417 | 2009 |
| A genome-wide association meta-analysis identifies new childhood obesity loci JP Bradfield, HR Taal, NJ Timpson, A Scherag, C Lecoeur, ... Nature genetics 44 (5), 526, 2012 | 410 | 2012 |
| CFH haplotypes without the Y402H coding variant show strong association with susceptibility to age-related macular degeneration M Li, P Atmaca-Sonmez, M Othman, KEH Branham, R Khanna, MS Wade, ... Nature genetics 38 (9), 1049-1054, 2006 | 378 | 2006 |
Hakon HakonarsonDirector, Center for Applied Genomics, CHOP, UPENNGeverifieerd e-mailadres voor email.chop.edu
