A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts R Li, J Liang, S Ni, T Zhou, X Qing, H Li, W He, J Chen, F Li, Q Zhuang, ... Cell stem cell 7 (1), 51-63, 2010 | 1334 | 2010 |
Modeling Parkinson’s disease in midbrain-like organoids LM Smits, L Reinhardt, P Reinhardt, M Glatza, AS Monzel, N Stanslowsky, ... NPJ Parkinson's disease 5 (1), 5, 2019 | 235 | 2019 |
3D cultures of Parkinson's disease‐specific dopaminergic neurons for high content phenotyping and drug testing S Bolognin, M Fossépré, X Qing, J Jarazo, J Ščančar, EL Moreno, ... Advanced Science 6 (1), 1800927, 2019 | 114 | 2019 |
FACS-assisted CRISPR-Cas9 genome editing facilitates Parkinson's disease modeling J Arias-Fuenzalida, J Jarazo, X Qing, J Walter, G Gomez-Giro, SL Nickels, ... Stem Cell Reports 9 (5), 1423-1431, 2017 | 98 | 2017 |
Neural stem cells of Parkinson's disease patients exhibit aberrant mitochondrial morphology and functionality J Walter, S Bolognin, PMA Antony, SL Nickels, SK Poovathingal, ... Stem cell reports 12 (5), 878-889, 2019 | 86 | 2019 |
Nurr1: RXRα heterodimer activation as monotherapy for Parkinson’s disease AD Spathis, X Asvos, D Ziavra, T Karampelas, S Topouzis, Z Cournia, ... Proceedings of the National Academy of Sciences 114 (15), 3999-4004, 2017 | 77 | 2017 |
CRISPR/Cas9 and piggyBac-mediated footprint-free LRRK2-G2019S knock-in reveals neuronal complexity phenotypes and α-Synuclein modulation in dopaminergic neurons X Qing, J Walter, J Jarazo, J Arias-Fuenzalida, AL Hillje, JC Schwamborn Stem Cell Research 24, 44-50, 2017 | 73 | 2017 |
Parkinson's disease phenotypes in patient neuronal cultures and brain organoids improved by 2‐Hydroxypropyl‐β‐Cyclodextrin treatment J Jarazo, K Barmpa, J Modamio, C Saraiva, S Sabaté‐Soler, I Rosety, ... Movement Disorders 37 (1), 80-94, 2022 | 45 | 2022 |
The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1 J Walter, S Bolognin, SK Poovathingal, S Magni, D Gerard, PMA Antony, ... Cell Reports 37 (3), 2021 | 24 | 2021 |
Class IIa histone deacetylases and myocyte enhancer factor 2 proteins regulate the mesenchymal-to-epithelial transition of somatic cell reprogramming Q Zhuang, X Qing, Y Ying, H Wu, C Benda, J Lin, Z Huang, L Liu, Y Xu, ... Journal of Biological Chemistry 288 (17), 12022-12031, 2013 | 21 | 2013 |
Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients SL Nickels, J Walter, S Bolognin, D Gérard, C Jaeger, X Qing, J Tisserand, ... Parkinsonism & Related Disorders 67, 48-55, 2019 | 20 | 2019 |
The N-terminal BRCT domain determines MCPH1 function in brain development and fertility X Liu, N Schneble-Löhnert, M Kristofova, X Qing, J Labisch, S Hofmann, ... Cell death & disease 12 (2), 143, 2021 | 15 | 2021 |
Nuclear-cytoplasmic shuttling of class IIa histone deacetylases regulates somatic cell reprogramming Z Luo, X Qing, C Benda, Z Huang, M Zhang, Y Huang, H Zhang, L Wang, ... Cell Regeneration 8 (1), 21-29, 2019 | 13 | 2019 |
Guidelines for fluorescent guided biallelic HDR targeting selection with PiggyBac system removal for gene editing J Jarazo, X Qing, JC Schwamborn Frontiers in Genetics 10, 190, 2019 | 11 | 2019 |
Parkinson’s disease phenotypes in patient specific brain organoids are improved by HP-β-CD treatment J Jarazo, K Barmpa, I Rosety, LM Smits, J Arias-Fuenzalida, J Walter, ... BioRxiv, 813089, 2019 | 10 | 2019 |
DNA damage response in neurodevelopment and neuromaintenance X Qing, G Zhang, ZQ Wang The FEBS Journal 290 (13), 3300-3310, 2023 | 9 | 2023 |
The Essential DNA Damage Response Complex MRN Is Dispensable for the Survival and Function of Purkinje Neurons M Ding, X Qing, G Zhang, C Baade-Büttner, R Gruber, H Lu, DO Ferguson, ... Frontiers in aging neuroscience 13, 786199, 2022 | 2 | 2022 |
Means and methods for selecting transformed cells JA Fuenzalida, J Jarazo, J Schwamborn, X Qing US Patent App. 16/073,005, 2020 | 1 | 2020 |
CRISPR/CAS9 AND PIGGYBAC MEDIATED LRRK2-G2019S IN VITRO PARKINSON’S DISEASE MODELING X Qing University of Luxembourg, Belval, Luxembourg, 2017 | | 2017 |
Parkinson's disease associated embryonic neurodevelopmental phenotypes J Walter, S Nickels, J Arias, X Qing, J Jarazo, F Noel, K Tronstad, ... HUMAN GENE THERAPY 27 (11), A80-A80, 2016 | | 2016 |