| Cell type–specific delivery of siRNAs with aptamer-siRNA chimeras JO McNamara, ER Andrechek, Y Wang, KD Viles, RE Rempel, E Gilboa, ... Nature biotechnology 24 (8), 1005-1015, 2006 | 1316 | 2006 |
| The E2F1–3 transcription factors are essential for cellular proliferation L Wu, C Timmers, B Maiti, HI Saavedra, L Sang, GT Chong, F Nuckolls, ... Nature 414 (6862), 457-462, 2001 | 761 | 2001 |
| Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors JP Dassie, X Liu, GS Thomas, RM Whitaker, KW Thiel, KR Stockdale, ... Nature biotechnology 27 (9), 839-846, 2009 | 701 | 2009 |
| Cardiovascular transition at birth: a physiological sequence SB Hooper, AB Te Pas, J Lang, JJ van Vonderen, CC Roehr, M Kluckow, ... Pediatric research 77 (5), 608-614, 2015 | 573* | 2015 |
| The opposing transcriptional activities of the two isoforms of the human progesterone receptor are due to differential cofactor binding PH Giangrande, EA Kimbrel, DP Edwards, DP McDonnell Molecular and cellular biology, 2000 | 447 | 2000 |
| The opposing transcriptional activities of the two isoforms of the human progesterone receptor are due to differential cofactor binding PH Giangrande, EA Kimbrel, DP Edwards, DP McDonnell Molecular and cellular biology, 2000 | 447 | 2000 |
| The A and B isoforms of the human progesterone receptor: two functionally different transcription factors encoded by a single gene. PH Giangrande, DP McDonnell Recent progress in hormone research 54, 291-313; discussion 313, 1999 | 420 | 1999 |
| E2Fs link the control of G1/S and G2/M transcription W Zhu, PH Giangrande, JR Nevins The EMBO journal 23 (23), 4615-4626, 2004 | 381 | 2004 |
| Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice JO McNamara, D Kolonias, F Pastor, RS Mittler, L Chen, PH Giangrande, ... The Journal of clinical investigation 118 (1), 376-386, 2008 | 357 | 2008 |
| Myc requires distinct E2F activities to induce S phase and apoptosis G Leone, R Sears, E Huang, R Rempel, F Nuckolls, CH Park, ... Molecular cell 8 (1), 105-113, 2001 | 325 | 2001 |
| Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay F Pastor, D Kolonias, PH Giangrande, E Gilboa Nature 465 (7295), 227-230, 2010 | 323 | 2010 |
| Reduction of chromium (VI) by ascorbate leads to chromium-DNA binding and DNA strand breaks in vitro DM Stearns, LJ Kennedy, KD Courtney, PH Giangrande, LS Phieffer, ... Biochemistry 34 (3), 910-919, 1995 | 278 | 1995 |
| Delivery of chemo-sensitizing siRNAs to HER2+-breast cancer cells using RNA aptamers KW Thiel, LI Hernandez, JP Dassie, WH Thiel, X Liu, KR Stockdale, ... Nucleic acids research 40 (13), 6319-6337, 2012 | 246 | 2012 |
| Mapping and characterization of the functional domains responsible for the differential activity of the A and B isoforms of the human progesterone receptor PH Giangrande, G Pollio, DP McDonnell Journal of Biological Chemistry 272 (52), 32889-32900, 1997 | 243 | 1997 |
| Therapeutic applications of DNA and RNA aptamers KW Thiel, PH Giangrande Oligonucleotides 19 (3), 209-222, 2009 | 209 | 2009 |
| Hormone-Dependent Interaction between the Amino- and Carboxyl-Terminal Domains of Progesterone Receptor in Vitro and in Vivo MJ Tetel, PH Giangrande, SA Leonhardt, DP McDonnell, DP Edwards Molecular endocrinology 13 (6), 910-924, 1999 | 208 | 1999 |
| Multifunctional aptamer-miRNA conjugates for targeted cancer therapy CL Esposito, L Cerchia, S Catuogno, G De Vita, JP Dassie, G Santamaria, ... Molecular therapy 22 (6), 1151-1163, 2014 | 177 | 2014 |
| Rational truncation of an RNA aptamer to prostate-specific membrane antigen using computational structural modeling WM Rockey, FJ Hernandez, SY Huang, S Cao, CA Howell, GS Thomas, ... Nucleic acid therapeutics 21 (5), 299-314, 2011 | 144 | 2011 |
| Rapid identification of cell-specific, internalizing RNA aptamers with bioinformatics analyses of a cell-based aptamer selection WH Thiel, T Bair, AS Peek, X Liu, J Dassie, KR Stockdale, MA Behlke, ... Public Library of Science 7 (9), e43836, 2012 | 143 | 2012 |
| A role for E2F6 in distinguishing G1/S-and G2/M-specific transcription PH Giangrande, W Zhu, S Schlisio, X Sun, S Mori, S Gaubatz, JR Nevins Genes & development 18 (23), 2941-2951, 2004 | 136 | 2004 |
