The tobacco-specific carcinogen NNK induces DNA methyltransferase 1 accumulation and tumor suppressor gene hypermethylation in mice and lung cancer patients RK Lin, YS Hsieh, P Lin, HS Hsu, CY Chen, YA Tang, CF Lee, YC Wang The Journal of clinical investigation 120 (2), 521-532, 2010 | 241 | 2010 |
Hypoxic tumor microenvironment activates GLI2 via HIF-1α and TGF-β2 to promote chemoresistance in colorectal cancer YA Tang, Y Chen, Y Bao, S Mahara, SMJM Yatim, G Oguz, PL Lee, ... Proceedings of the National Academy of Sciences, 201801348, 2018 | 235 | 2018 |
Dysregulation of p53/Sp1 control leads to DNA methyltransferase-1 overexpression in lung cancer RK Lin, CY Wu, JW Chang, LJ Juan, HS Hsu, CY Chen, YY Lu, YA Tang, ... Cancer research 70 (14), 5807-5817, 2010 | 212 | 2010 |
Oct4 transcriptionally regulates the expression of long non-coding RNAs NEAT1 and MALAT1 to promote lung cancer progression J Jen, YA Tang, YH Lu, CC Lin, WW Lai, YC Wang Molecular Cancer 16 (1), 104, 2017 | 202 | 2017 |
A novel sialyltransferase inhibitor suppresses FAK/paxillin signaling and cancer angiogenesis and metastasis pathways JY Chen, YA Tang, SM Huang, HF Juan, LW Wu, YC Sun, SC Wang, ... Cancer research, 2011 | 144 | 2011 |
Promoter hypermethylation is the predominant mechanism in hMLH1 and hMSH2 deregulation and is a poor prognostic factor in nonsmoking lung cancer HS Hsu, CK Wen, YA Tang, RK Lin, WY Li, WH Hsu, YC Wang Clinical cancer research 11 (15), 5410-5416, 2005 | 98 | 2005 |
MDM2 overexpression deregulates the transcriptional control of RB/E2F leading to DNA methyltransferase 3A overexpression in lung cancer YA Tang, RK Lin, YT Tsai, HS Hsu, YC Yang, CY Chen, YC Wang Clinical cancer research 18 (16), 4325-4333, 2012 | 66 | 2012 |
A novel histone deacetylase inhibitor exhibits antitumor activity via apoptosis induction, F-actin disruption and gene acetylation in lung cancer YA Tang, WL Wen, JW Chang, TT Wei, YHC Tan, S Salunke, CT Chen, ... PloS one 5 (9), e12417, 2010 | 65 | 2010 |
Global Oct4 target gene analysis reveals novel downstream PTEN and TNC genes required for drug-resistance and metastasis in lung cancer YA Tang, CH Chen, HS Sun, CP Cheng, VS Tseng, HS Hsu, WC Su, ... Nucleic acids research 43 (3), 1593-1608, 2015 | 61 | 2015 |
DNMT3B overexpression by deregulation of FOXO3a-mediated transcription repression and MDM2 overexpression in lung cancer YC Yang, YA Tang, JM Shieh, RK Lin, HS Hsu, YC Wang Journal of Thoracic Oncology 9 (9), 1305-1315, 2014 | 47 | 2014 |
Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer J Jen, LL Lin, HT Chen, SY Liao, FY Lo, YA Tang, WC Su, R Salgia, ... Oncogene, 2015 | 42 | 2015 |
A synthetic podophyllotoxin derivative exerts anti-cancer effects by inducing mitotic arrest and pro-apoptotic ER stress in lung cancer preclinical models JY Chen, YA Tang, WS Li, YC Chiou, JM Shieh, YC Wang PloS one 8 (4), e62082, 2013 | 41 | 2013 |
Deregulation of SLIT2-Mediated Cdc42 Activity Is Associated with Esophageal Cancer Metastasis and Poor Prognosis RC Tseng, JM Chang, JH Chen, WR Huang, YA Tang, IY Kuo, JJ Yan, ... Journal of Thoracic Oncology 10 (1), 189-198, 2015 | 36 | 2015 |
A histone deacetylase inhibitor enhances expression of genes inhibiting Wnt pathway and augments activity of DNA demethylation reagent against nonsmall‐cell lung cancer JM Shieh, YA Tang, FH Hu, WJ Huang, YJ Wang, J Jen, SY Liao, YH Lu, ... International Journal of Cancer 140 (10), 2375-2386, 2017 | 30 | 2017 |
Lack of association of C-Met-N375S sequence variant with lung cancer susceptibility and prognosis JM Shieh, YA Tang, TH Yang, CY Chen, HS Hsu, YHC Tan, R Salgia, ... International journal of medical sciences 10 (8), 988, 2013 | 30 | 2013 |
Mitochondrial apoptosis and FAK signaling disruption by a novel histone deacetylase inhibitor, HTPB, in antitumor and antimetastatic mouse models JM Shieh, TT Wei, YA Tang, SM Huang, WL Wen, MY Chen, HC Cheng, ... PloS one 7 (1), e30240, 2012 | 26 | 2012 |
A histone deacetylase inhibitor YCW1 with antitumor and antimetastasis properties enhances cisplatin activity against non-small cell lung cancer in preclinical studies WJ Huang, YA Tang, MY Chen, YJ Wang, FH Hu, TW Wang, SW Chao, ... Cancer letters 346 (1), 84-93, 2014 | 25 | 2014 |
Phosphorylation of Rab37 by protein kinase C alpha inhibits the exocytosis function and metastasis suppression activity of Rab37 HT Tzeng, TH Li, YA Tang, CH Tsai, PJF Lu, WW Lai, CW Chiang, ... Oncotarget 8 (65), 108556, 2017 | 16 | 2017 |
探討 DNA 甲基轉移酵素和組蛋白去乙醯化酵素之變異機制及其抑制劑用於肺癌治療應用性 YA Tang 成功大學基礎醫學研究所學位論文, 1-140, 2012 | | 2012 |