Notch-dependent EMT is attenuated in patients with aortic aneurysm and bicuspid aortic valve AS Kostina, VЕ Uspensky, OB Irtyuga, EV Ignatieva, O Freylikhman, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (4), 733-740, 2016 | 82 | 2016 |
Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease CV Theodoris, P Zhou, L Liu, Y Zhang, T Nishino, Y Huang, A Kostina, ... Science 371 (6530), eabd0724, 2021 | 67 | 2021 |
Phenotypic and functional changes of endothelial and smooth muscle cells in thoracic aortic aneurysms A Malashicheva, D Kostina, A Kostina, O Irtyuga, I Voronkina, L Smagina, ... International journal of vascular medicine 2016, 2016 | 64 | 2016 |
Different Notch signaling in cells from calcified bicuspid and tricuspid aortic valves A Kostina, A Shishkova, E Ignatieva, O Irtyuga, M Bogdanova, K Levchuk, ... Journal of molecular and cellular cardiology 114, 211-219, 2018 | 57 | 2018 |
Inflammation and mechanical stress stimulate osteogenic differentiation of human aortic valve interstitial cells M Bogdanova, A Kostina, K Zihlavnikova Enayati, A Zabirnyk, ... Frontiers in physiology 9, 1635, 2018 | 48 | 2018 |
Dose-dependent mechanism of Notch action in promoting osteogenic differentiation of mesenchymal stem cells D Semenova, M Bogdanova, A Kostina, A Golovkin, A Kostareva, ... Cell and tissue research 379 (1), 169-179, 2020 | 44 | 2020 |
The Notch pathway: a novel therapeutic target for cardiovascular diseases? G Aquila, A Kostina, F Vieceli Dalla Sega, E Shlyakhto, A Kostareva, ... Expert opinion on therapeutic targets 23 (8), 695-710, 2019 | 42 | 2019 |
Notch, BMP and WNT/β-catenin network is impaired in endothelial cells of the patients with thoracic aortic aneurysm A Kostina, H Bjork, E Ignatieva, O Irtyuga, V Uspensky, D Semenova, ... Atherosclerosis Supplements 35, e6-e13, 2018 | 26 | 2018 |
Notch signaling in the pathogenesis of thoracic aortic aneurysms: A bridge between embryonic and adult states A Malashicheva, A Kostina, A Kostareva, O Irtyuga, M Gordeev, ... Biochimica Et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (3), 165631, 2020 | 23 | 2020 |
Cellular mechanisms of aortic valve calcification EV Zhiduleva, OB Irtyuga, AA Shishkova, EV Ignat’eva, AS Kostina, ... Bulletin of Experimental Biology and Medicine 164 (3), 371-375, 2018 | 23 | 2018 |
Human aortic endothelial cells have osteogenic Notch-dependent properties in co-culture with aortic smooth muscle cells A Kostina, D Semenova, D Kostina, V Uspensky, A Kostareva, ... Biochemical and biophysical research communications 514 (2), 462-468, 2019 | 22 | 2019 |
Altered DNA methylation indicates an oscillatory flow mediated epithelial-to-mesenchymal transition signature in ascending aorta of patients with bicuspid aortic valve HM Björck, L Du, S Pulignani, V Paloschi, K Lundströmer, AS Kostina, ... Scientific Reports 8 (1), 2777, 2018 | 19 | 2018 |
Altered DNA methylation indicates an oscillatory flow mediated epithelial-to-mesenchymal transition signature in ascending aorta of patients with bicuspid aortic valve HM Bjorck, L Du, S Pulignani, V Paloschi, K Lundstromer, AS Kostina, ... SCIENTIFIC REPORTS 8, 2018 | 14 | 2018 |
Context-specific osteogenic potential of mesenchymal stem cells A Kostina, A Lobov, D Semenova, A Kiselev, P Klausen, A Malashicheva Biomedicines 9 (6), 673, 2021 | 9 | 2021 |
Dysregulation of Notch signaling in cardiac mesenchymal cells of patients with tetralogy of Fallot I Kozyrev, P Dokshin, A Kostina, A Kiselev, E Ignatieva, A Golovkin, ... Pediatric Research 88 (1), 38-47, 2020 | 9 | 2020 |
A patterned human heart tube organoid model generated by pluripotent stem cell self-assembly B Volmert, A Riggs, F Wang, A Juhong, A Kiselev, A Kostina, C O’hern, ... bioRxiv, 2022.12. 16.519611, 2022 | 7 | 2022 |
A patterned human primitive heart organoid model generated by pluripotent stem cell self-organization B Volmert, A Kiselev, A Juhong, F Wang, A Riggs, A Kostina, C O’Hern, ... Nature Communications 14 (1), 8245, 2023 | 6 | 2023 |
Uspensky Vcapital Ie C, Irtyuga OB, Ignatieva EV, Freylikhman O, Gavriliuk ND, et al. Notch-dependent EMT is attenuated in patients with aortic aneurysm and bicuspid aortic valve AS Kostina Biochim Biophys Acta 4, 733-40, 1862 | 6 | 1862 |
ER stress and lipid imbalance drive embryonic cardiomyopathy in a human heart organoid model of pregestational diabetes A Kostina, YR Lewis-Israeli, M Abdelhamid, MA Gabalski, BD Volmert, ... bioRxiv, 2023 | 5 | 2023 |
Human heart organoids: current applications and future perspectives A Kostina, B Volmert, A Aguirre European Heart Journal 45 (10), 751-753, 2024 | 3 | 2024 |