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Aleksandra Kostina
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Notch-dependent EMT is attenuated in patients with aortic aneurysm and bicuspid aortic valve
AS Kostina, VЕ Uspensky, OB Irtyuga, EV Ignatieva, O Freylikhman, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (4), 733-740, 2016
822016
Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease
CV Theodoris, P Zhou, L Liu, Y Zhang, T Nishino, Y Huang, A Kostina, ...
Science 371 (6530), eabd0724, 2021
672021
Phenotypic and functional changes of endothelial and smooth muscle cells in thoracic aortic aneurysms
A Malashicheva, D Kostina, A Kostina, O Irtyuga, I Voronkina, L Smagina, ...
International journal of vascular medicine 2016, 2016
642016
Different Notch signaling in cells from calcified bicuspid and tricuspid aortic valves
A Kostina, A Shishkova, E Ignatieva, O Irtyuga, M Bogdanova, K Levchuk, ...
Journal of molecular and cellular cardiology 114, 211-219, 2018
572018
Inflammation and mechanical stress stimulate osteogenic differentiation of human aortic valve interstitial cells
M Bogdanova, A Kostina, K Zihlavnikova Enayati, A Zabirnyk, ...
Frontiers in physiology 9, 1635, 2018
482018
Dose-dependent mechanism of Notch action in promoting osteogenic differentiation of mesenchymal stem cells
D Semenova, M Bogdanova, A Kostina, A Golovkin, A Kostareva, ...
Cell and tissue research 379 (1), 169-179, 2020
442020
The Notch pathway: a novel therapeutic target for cardiovascular diseases?
G Aquila, A Kostina, F Vieceli Dalla Sega, E Shlyakhto, A Kostareva, ...
Expert opinion on therapeutic targets 23 (8), 695-710, 2019
422019
Notch, BMP and WNT/β-catenin network is impaired in endothelial cells of the patients with thoracic aortic aneurysm
A Kostina, H Bjork, E Ignatieva, O Irtyuga, V Uspensky, D Semenova, ...
Atherosclerosis Supplements 35, e6-e13, 2018
262018
Notch signaling in the pathogenesis of thoracic aortic aneurysms: A bridge between embryonic and adult states
A Malashicheva, A Kostina, A Kostareva, O Irtyuga, M Gordeev, ...
Biochimica Et Biophysica Acta (BBA)-Molecular Basis of Disease 1866 (3), 165631, 2020
232020
Cellular mechanisms of aortic valve calcification
EV Zhiduleva, OB Irtyuga, AA Shishkova, EV Ignat’eva, AS Kostina, ...
Bulletin of Experimental Biology and Medicine 164 (3), 371-375, 2018
232018
Human aortic endothelial cells have osteogenic Notch-dependent properties in co-culture with aortic smooth muscle cells
A Kostina, D Semenova, D Kostina, V Uspensky, A Kostareva, ...
Biochemical and biophysical research communications 514 (2), 462-468, 2019
222019
Altered DNA methylation indicates an oscillatory flow mediated epithelial-to-mesenchymal transition signature in ascending aorta of patients with bicuspid aortic valve
HM Björck, L Du, S Pulignani, V Paloschi, K Lundströmer, AS Kostina, ...
Scientific Reports 8 (1), 2777, 2018
192018
Altered DNA methylation indicates an oscillatory flow mediated epithelial-to-mesenchymal transition signature in ascending aorta of patients with bicuspid aortic valve
HM Bjorck, L Du, S Pulignani, V Paloschi, K Lundstromer, AS Kostina, ...
SCIENTIFIC REPORTS 8, 2018
142018
Context-specific osteogenic potential of mesenchymal stem cells
A Kostina, A Lobov, D Semenova, A Kiselev, P Klausen, A Malashicheva
Biomedicines 9 (6), 673, 2021
92021
Dysregulation of Notch signaling in cardiac mesenchymal cells of patients with tetralogy of Fallot
I Kozyrev, P Dokshin, A Kostina, A Kiselev, E Ignatieva, A Golovkin, ...
Pediatric Research 88 (1), 38-47, 2020
92020
A patterned human heart tube organoid model generated by pluripotent stem cell self-assembly
B Volmert, A Riggs, F Wang, A Juhong, A Kiselev, A Kostina, C O’hern, ...
bioRxiv, 2022.12. 16.519611, 2022
72022
A patterned human primitive heart organoid model generated by pluripotent stem cell self-organization
B Volmert, A Kiselev, A Juhong, F Wang, A Riggs, A Kostina, C O’Hern, ...
Nature Communications 14 (1), 8245, 2023
62023
Uspensky Vcapital Ie C, Irtyuga OB, Ignatieva EV, Freylikhman O, Gavriliuk ND, et al. Notch-dependent EMT is attenuated in patients with aortic aneurysm and bicuspid aortic valve
AS Kostina
Biochim Biophys Acta 4, 733-40, 1862
61862
ER stress and lipid imbalance drive embryonic cardiomyopathy in a human heart organoid model of pregestational diabetes
A Kostina, YR Lewis-Israeli, M Abdelhamid, MA Gabalski, BD Volmert, ...
bioRxiv, 2023
52023
Human heart organoids: current applications and future perspectives
A Kostina, B Volmert, A Aguirre
European Heart Journal 45 (10), 751-753, 2024
32024
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Artikelen 1–20