Suivre
Alexander T Dilthey
Alexander T Dilthey
Institute of Medical Microbiology, University Hospital of Dusseldorf
Adresse e-mail validée de med.uni-duesseldorf.de
Titre
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Année
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
Nature 476 (7359), 214-219, 2011
29912011
Nanopore sequencing and assembly of a human genome with ultra-long reads
M Jain, S Koren, KH Miga, J Quick, AC Rand, TA Sasani, JR Tyson, ...
Nature biotechnology 36 (4), 338-345, 2018
18892018
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
International IBD Genetics Consortium (IIBDGC), C Agliardi, L Alfredsson, ...
Nature genetics 45 (11), 1353-1360, 2013
13412013
Severe COVID-19 is marked by a dysregulated myeloid cell compartment
J Schulte-Schrepping, N Reusch, D Paclik, K Baßler, S Schlickeiser, ...
Cell 182 (6), 1419-1440. e23, 2020
12862020
Genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
A Strange, F Capon, CCA Spencer, J Knight, ME Weale, MH Allen, ...
Nature genetics 42 (11), 985, 2010
10252010
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility
Australo-Anglo-American Spondyloarthritis Consortium (TASC), ...
Nature genetics 43 (8), 761-767, 2011
9682011
Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles
BP Fairfax, S Makino, J Radhakrishnan, K Plant, S Leslie, A Dilthey, ...
Nature genetics 44 (5), 502-510, 2012
5692012
SARS‐CoV‐2 targets neurons of 3D human brain organoids
A Ramani, L Müller, PN Ostermann, E Gabriel, P Abida‐Islam, ...
The EMBO journal 39 (20), e106230, 2020
4632020
De novo assembly of haplotype-resolved genomes with trio binning
S Koren, A Rhie, BP Walenz, AT Dilthey, DM Bickhart, SB Kingan, ...
Nature biotechnology 36 (12), 1174-1182, 2018
4072018
Class II HLA interactions modulate genetic risk for multiple sclerosis
Nature genetics 47 (10), 1107-1113, 2015
3992015
Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19
JP Bernardes, N Mishra, F Tran, T Bahmer, L Best, JI Blase, D Bordoni, ...
Immunity 53 (6), 1296-1314. e9, 2020
3032020
Improved genome inference in the MHC using a population reference graph
A Dilthey, C Cox, Z Iqbal, MR Nelson, G McVean
Nature genetics 47 (6), 682-688, 2015
2372015
Multi-population classical HLA type imputation
A Dilthey, S Leslie, L Moutsianas, J Shen, C Cox, MR Nelson, G McVean
PLoS computational biology 9 (2), e1002877, 2013
2032013
DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis
L Kular, Y Liu, S Ruhrmann, G Zheleznyakova, F Marabita, ...
Nature communications 9 (1), 2397, 2018
1902018
HLA* IMP—an integrated framework for imputing classical HLA alleles from SNP genotypes
AT Dilthey, L Moutsianas, S Leslie, G McVean
Bioinformatics 27 (7), 968-972, 2011
1822011
Early IFN-α signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19
B Krämer, R Knoll, L Bonaguro, M ToVinh, J Raabe, ...
Immunity 54 (11), 2650-2669. e14, 2021
1772021
Molecular mimicry between Anoctamin 2 and Epstein-Barr virus nuclear antigen 1 associates with multiple sclerosis risk
K Tengvall, J Huang, C Hellström, P Kammer, M Biström, B Ayoglu, ...
Proceedings of the National Academy of Sciences 116 (34), 16955-16960, 2019
1632019
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
Nature genetics 42 (11), 985-990, 2010
1512010
A fast adaptive algorithm for computing whole-genome homology maps
C Jain, S Koren, A Dilthey, AM Phillippy, S Aluru
Bioinformatics 34 (17), i748-i756, 2018
1442018
Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania
Nature communications 10 (1), 5732, 2019
1402019
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