| Discovery of begacestat, a Notch-1-sparing γ-secretase inhibitor for the treatment of Alzheimer’s disease SC Mayer, AF Kreft, B Harrison, M Abou-Gharbia, M Antane, S Aschmies, ... Journal of medicinal chemistry 51 (23), 7348-7351, 2008 | 146 | 2008 |
| The Scope and Mechanism of Phosphonium-Mediated SNAr Reactions in Heterocyclic Amides and Ureas ZK Wan, S Wacharasindhu, CG Levins, M Lin, K Tabei, TS Mansour The Journal of Organic Chemistry 72 (26), 10194-10210, 2007 | 125 | 2007 |
| Chemical exchange in diffusion NMR experiments AD Chen, CS Johnson, M Lin, MJ Shapiro Journal of the American Chemical Society 120 (35), 9094-9095, 1998 | 105 | 1998 |
| Protecting group free radical C–H trifluoromethylation of peptides N Ichiishi, JP Caldwell, M Lin, W Zhong, X Zhu, E Streckfuss, HY Kim, ... Chemical science 9 (17), 4168-4175, 2018 | 102 | 2018 |
| Direct Oxa-Pictet−Spengler Cyclization to the Natural (3a,5)-trans-Stereochemistry in the Syntheses of (+)-7-Deoxyfrenolicin B and (+)-7-Deoxykalafungin CN Eid, J Shim, J Bikker, M Lin The Journal of Organic Chemistry 74 (1), 423-426, 2009 | 43 | 2009 |
| Use of 1H NMR to facilitate solubility measurement for drug discovery compounds M Lin, M Tesconi, M Tischler International journal of pharmaceutics 369 (1-2), 47-52, 2009 | 36 | 2009 |
| Dimethyl sulfoxide mediated elimination reactions in 3-aryl 2, 3-dihalopropanoates: Scope and mechanistic insights W Li, J Li, M Lin, S Wacharasindhu, K Tabei, TS Mansour The Journal of Organic Chemistry 72 (16), 6016-6021, 2007 | 28 | 2007 |
| First Scale-Up: Problems and Resolutions on the Synthesis of WAY-253752, a Novel, Dual-Acting SSRI/5HT1A Antagonist A Nikitenko, D Evrard, AL Sabb, RL Vogel, G Stack, M Young, M Lin, ... Organic Process Research & Development 12 (1), 76-80, 2008 | 24 | 2008 |
| C-5 substituted heteroaryl-3-pyridinecarbonitriles as PKCθ inhibitors: Part II AS Prashad, D Wang, J Subrath, B Wu, M Lin, MY Zhang, N Kagan, J Lee, ... Bioorganic & medicinal chemistry letters 19 (19), 5799-5802, 2009 | 20 | 2009 |
| A multidisciplinary approach to identify a degradation product in a pharmaceutical dosage form C Pan, J Guan, M Lin Journal of pharmaceutical and biomedical analysis 54 (4), 855-859, 2011 | 15 | 2011 |
| Synthesis of 7-(E)-alkenyl-4-amino-3-quinolinecarbonitriles via Pd-mediated Heck, Stille, and Suzuki reactions YD Wang, M Dutia, MB Floyd, AS Prashad, D Berger, M Lin Tetrahedron 65 (1), 57-61, 2009 | 14 | 2009 |
| SAR exploration at the C-3 position of tetrahydro-β-carboline sstr3 antagonists S He, PH Dobbelaar, L Guo, Z Ye, J Liu, T Jian, Q Truong, SK Shah, W Du, ... Bioorganic & Medicinal Chemistry Letters 26 (6), 1529-1535, 2016 | 12 | 2016 |
| Pharmaceutical dosage forms and compositions K Ghosh, A Nagi, X Pan, M Lin, L Linberg, P Cai, E Browne, M Bernatchez, ... US Patent App. 11/082,548, 2005 | 11 | 2005 |
| Chemical interactions between an active pharmaceutical ingredient and its counterion in a tromethamine salt under forced degradation conditions E Loeser, P Sutton, A Skorodinsky, M Lin, G Yowell Drug Development and Industrial Pharmacy 38 (3), 357-364, 2012 | 10 | 2012 |
| Facile and practical synthesis of a cannabinoid-1 antagonist via regio-and stereoselective ring-opening of an aziridinium ion EB Villhauer, WC Shieh, Z Du, K Vargas, L Ciszewski, Y Lu, M Girgis, ... Tetrahedron 65 (45), 9067-9074, 2009 | 9 | 2009 |
| Pharmaceutical dosage forms and compositions K Ghosh, A Nagi, X Pan, M Lin, L Linberg, P Cai, E Browne, M Bernatchez, ... US Patent App. 11/517,605, 2007 | 9 | 2007 |
| Pradigastat disposition in humans: in vivo and in vitro investigations A Upthagrove, J Chen, CD Meyers, K Kulmatycki, A Bretz, L Wang, ... Xenobiotica 47 (12), 1077-1089, 2017 | 7 | 2017 |
| Good Christian Hombre Fletcher Flannel Fletcher Christian Good nqSTaTW087 for clumsy. orkutpro. com N Ichiishi, JP Caldwell, M Lin, W Zhong, X Zhu, E Streckfuss, HY Kim, ... Good Christian Hombre Fletcher Flannel Fletcher Christian Good nqSTaTW087 …, 2018 | 1 | 2018 |
| Synthetic studies of [M+ 5] hydroxymidazolam Z Jian, A Wu, M Lin, L Jones, T Ray JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS 53 (5-6), 265-268, 2010 | 1 | 2010 |
| Pharmaceutical dosage forms and compositions K Ghosh, AS Nagi, X Pan, M Lin, L Linberg, P Cai, ENC Browne, ... TW Patent App. 095,132,852 A, 2008 | 1 | 2008 |
