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Andrew Sinclair
Andrew Sinclair
Scientist, Taproot Medical Technologies - prev. University of Washington Chemical Engineering
Geverifieerd e-mailadres voor uw.edu
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Zwitterionic gel encapsulation promotes protein stability, enhances pharmacokinetics, and reduces immunogenicity
P Zhang, F Sun, C Tsao, S Liu, P Jain, A Sinclair, HC Hung, T Bai, K Wu, ...
Proceedings of the National Academy of Sciences 112 (39), 12046-12051, 2015
2742015
Expansion of primitive human hematopoietic stem cells by culture in a zwitterionic hydrogel
T Bai, J Li, A Sinclair, S Imren, F Merriam, F Sun, MB O’Kelly, C Nourigat, ...
Nature medicine 25 (10), 1566-1575, 2019
2022019
Hierarchical zwitterionic modification of a SERS substrate enables real-time drug monitoring in blood plasma
F Sun, HC Hung, A Sinclair, P Zhang, T Bai, DD Galvan, P Jain, B Li, ...
Nature communications 7 (1), 13437, 2016
1902016
Zwitterionic fusion in hydrogels and spontaneous and time-independent self-healing under physiological conditions
T Bai, S Liu, F Sun, A Sinclair, L Zhang, Q Shao, S Jiang
Biomaterials 35 (13), 3926-3933, 2014
1362014
Self‐healing zwitterionic microgels as a versatile platform for malleable cell constructs and injectable therapies
A Sinclair, MB O'Kelly, T Bai, HC Hung, P Jain, S Jiang
Advanced Materials 30 (39), 1803087, 2018
1212018
Ultra-low fouling and high antibody loading zwitterionic hydrogel coatings for sensing and detection in complex media
YN Chou, F Sun, HC Hung, P Jain, A Sinclair, P Zhang, T Bai, Y Chang, ...
Acta biomaterialia 40, 31-37, 2016
882016
Restraint of the differentiation of mesenchymal stem cells by a nonfouling zwitterionic hydrogel
T Bai, F Sun, L Zhang, A Sinclair, S Liu, JR Ella‐Menye, Y Zheng, S Jiang
Angewandte Chemie 126 (47), 12943-12948, 2014
852014
High-strength and fibrous capsule–resistant zwitterionic elastomers
D Dong, C Tsao, HC Hung, F Yao, C Tang, L Niu, J Ma, J MacArthur, ...
Science advances 7 (1), eabc5442, 2021
812021
Zwitterionic nanocages overcome the efficacy loss of biologic drugs
B Li, Z Yuan, P Zhang, A Sinclair, P Jain, K Wu, C Tsao, J Xie, HC Hung, ...
Advanced Materials 30 (14), 1705728, 2018
742018
A Coating‐Free Nonfouling Polymeric Elastomer
HC Hung, P Jain, P Zhang, F Sun, A Sinclair, T Bai, B Li, K Wu, C Tsao, ...
Advanced Materials 29 (31), 1700617, 2017
692017
EKylation: addition of an alternating-charge peptide stabilizes proteins
EJ Liu, A Sinclair, AJ Keefe, BL Nannenga, BL Coyle, F Baneyx, S Jiang
Biomacromolecules 16 (10), 3357-3361, 2015
642015
Engineering buffering and hydrolytic or photolabile charge shifting in a polycarboxybetaine ester gene delivery platform
A Sinclair, T Bai, LR Carr, JR Ella-Menye, L Zhang, S Jiang
Biomacromolecules 14 (5), 1587-1593, 2013
512013
Directed neural stem cell differentiation on polyaniline-coated high strength hydrogels
B Xu, T Bai, A Sinclair, W Wang, Q Wu, F Gao, H Jia, S Jiang, W Liu
Materials Today Chemistry 1, 15-22, 2016
492016
Butyrylcholinesterase nanocapsule as a long circulating bioscavenger with reduced immune response
P Zhang, P Jain, C Tsao, A Sinclair, F Sun, HC Hung, T Bai, K Wu, S Jiang
Journal of controlled release 230, 73-78, 2016
452016
Hydrolytic cationic ester microparticles for highly efficient DNA vaccine delivery
L Zhang, A Sinclair, Z Cao, JR Ella‐Menye, X Xu, LR Carr, SH Pun, ...
Small 9 (20), 3439-3444, 2013
392013
Zwitterionic hydrogels based on a degradable disulfide carboxybetaine cross-linker
P Jain, HC Hung, B Li, J Ma, D Dong, X Lin, A Sinclair, P Zhang, ...
Langmuir 35 (5), 1864-1871, 2018
362018
Harnessing isomerization-mediated manipulation of nonspecific cell/matrix interactions to reversibly trigger and suspend stem cell differentiation
T Bai, A Sinclair, F Sun, P Jain, HC Hung, P Zhang, JR Ella-Menye, W Liu, ...
Chemical Science 7 (1), 333-338, 2016
352016
Functionalized zwitterionic and mixed charge polymers, related hydrogels, and methods for their use
S Jiang, T Bai, HS Sundaram, AW Sinclair, JR Ella-Menye, P Jain
US Patent 10,828,398, 2020
162020
Hierarchical design of a polymeric nanovehicle for efficient tumor regression and imaging
J An, Q Guo, P Zhang, A Sinclair, Y Zhao, X Zhang, K Wu, F Sun, ...
Nanoscale 8 (17), 9318-9327, 2016
142016
Functionalized Zwitterionic and mixed charge polymers, related hydrogels, and methods for their use
S Jiang, T Bai, HS Sundaram, AW Sinclair, JR Ella-Menye, P Jain
US Patent 10,272,180, 2019
122019
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Artikelen 1–20