MICE models: superior to the HERG model in predicting Torsade de Pointes J Kramer, CA Obejero-Paz, G Myatt, YA Kuryshev, A Bruening-Wright, ... Scientific reports 3 (1), 2100, 2013 | 349 | 2013 |
Mechanisms of arsenic-induced prolongation of cardiac repolarization E Ficker, YA Kuryshev, AT Dennis, C Obejero-Paz, L Wang, P Hawryluk, ... Molecular pharmacology 66 (1), 33-44, 2004 | 327 | 2004 |
Pentamidine-induced long QT syndrome and block of hERG trafficking YA Kuryshev, E Ficker, L Wang, P Hawryluk, AT Dennis, BA Wible, ... Journal of Pharmacology and Experimental Therapeutics 312 (1), 316-323, 2005 | 295 | 2005 |
Interactions of the 5-hydroxytryptamine 3 antagonist class of antiemetic drugs with human cardiac ion channels YA Kuryshev, AM Brown, L Wang, CR Benedict, D Rampe Journal of Pharmacology and Experimental Therapeutics 295 (2), 614-620, 2000 | 187 | 2000 |
HERG-Lite®: A novel comprehensive high-throughput screen for drug-induced hERG risk BA Wible, P Hawryluk, E Ficker, YA Kuryshev, G Kirsch, AM Brown Journal of pharmacological and toxicological methods 52 (1), 136-145, 2005 | 184 | 2005 |
Cloning and expression of a novel K+ channel regulatory protein, KChAP BA Wible, Q Yang, YA Kuryshev, EA Accili, AM Brown Journal of Biological Chemistry 273 (19), 11745-11751, 1998 | 156 | 1998 |
KChAP as a chaperone for specific K+channels YA Kuryshev, TI Gudz, AM Brown, BA Wible American Journal of Physiology-Cell Physiology 278 (5), C931-C941, 2000 | 146 | 2000 |
Assessment of an In Silico Mechanistic Model for Proarrhythmia Risk Prediction Under the CiPA Initiative Z Li, BJ Ridder, X Han, WW Wu, J Sheng, PN Tran, M Wu, A Randolph, ... Clinical Pharmacology & Therapeutics 105 (2), 466-475, 2019 | 135 | 2019 |
Decreased sodium and increased transient outward potassium currents in iron-loaded cardiac myocytes: implications for the arrhythmogenesis of human siderotic heart disease YA Kuryshev, GM Brittenham, H Fujioka, P Kannan, CC Shieh, SA Cohen, ... Circulation 100 (6), 675-683, 1999 | 122 | 1999 |
Alfuzosin delays cardiac repolarization by a novel mechanism AE Lacerda, YA Kuryshev, Y Chen, M Renganathan, H Eng, SJ Danthi, ... Journal of Pharmacology and Experimental Therapeutics 324 (2), 427-433, 2008 | 114 | 2008 |
Corticotropin-releasing hormone stimulates Ca2+ entry through L-and P-type Ca2+ channels in rat corticotropes YA Kuryshev, GV Childs, AK Ritchie Endocrinology 137 (6), 2269-2277, 1996 | 104 | 1996 |
Increased K+ efflux and apoptosis induced by the potassium channel modulatory protein KChAP/PIAS3β in prostate cancer cells BA Wible, L Wang, YA Kuryshev, A Basu, S Haldar, AM Brown Journal of Biological Chemistry 277 (20), 17852-17862, 2002 | 101 | 2002 |
Optical mapping reveals conduction slowing and impulse block in iron-overload cardiomyopathy KR Laurita, ET Chuck, T Yang, WQ Dong, YA Kuryshev, GM Brittenham, ... Journal of Laboratory and Clinical Medicine 142 (2), 83-89, 2003 | 79 | 2003 |
Corticotropin-releasing hormone stimulation of Ca2+ entry in corticotropes is partially dependent on protein kinase A YA Kuryshev, GV Childs, AK Ritchie Endocrinology 136 (9), 3925-3935, 1995 | 76 | 1995 |
KChAP/Kvβ1. 2 interactions and their effects on cardiac Kv channel expression YA Kuryshev, BA Wible, TI Gudz, AN Ramirez, AM Brown American Journal of Physiology-Cell Physiology 281 (1), C290-C299, 2001 | 73 | 2001 |
Corticotropin releasing hormone inhibits an inwardly rectifying potassium current in rat corticotropes. YA Kuryshev, L Haak, GV Childs, AK Ritchie The Journal of physiology 502 (Pt 2), 265, 1997 | 62 | 1997 |
Deferoxamine promotes survival and prevents electrocardiographic abnormalities in the gerbil model of iron-overload cardiomyopathy CA Obejero-Paz, T Yang, WQ Dong, MN Levy, GM Brittenham, ... Journal of Laboratory and Clinical Medicine 141 (2), 121-130, 2003 | 59 | 2003 |
Inhibition of human ether-a-go-go-related gene potassium channels by α1-adrenoceptor antagonists prazosin, doxazosin, and terazosin D Thomas, AB Wimmer, K Wu, BC Hammerling, EK Ficker, YA Kuryshev, ... Naunyn-Schmiedeberg's archives of pharmacology 369, 462-472, 2004 | 55 | 2004 |
Antimony-based antileishmanial compounds prolong the cardiac action potential by an increase in cardiac calcium currents YA Kuryshev, L Wang, BA Wible, X Wan, E Ficker Molecular pharmacology 69 (4), 1216-1225, 2006 | 50 | 2006 |
Inositol 1, 4, 5‐trisphosphate activates two types of Ca2+‐permeable channels in human carcinoma cells GN Mozhayeva, AP Naumov, YA Kuryshev FEBS letters 277 (1-2), 233-234, 1990 | 49 | 1990 |