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Tim Ebbels
Tim Ebbels
Professor of Biomedical Data Science, Imperial College London
Verified email at imperial.ac.uk - Homepage
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Year
Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts
O Beckonert, HC Keun, TMD Ebbels, J Bundy, E Holmes, JC Lindon, ...
Nature protocols 2 (11), 2692, 2007
22892007
Human metabolic phenotype diversity and its association with diet and blood pressure
E Holmes, RL Loo, J Stamler, M Bictash, IKS Yap, Q Chan, T Ebbels, ...
Nature 453 (7193), 396-400, 2008
11932008
Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project
JC Lindon, JK Nicholson, E Holmes, H Antti, ME Bollard, H Keun, ...
Toxicology and applied pharmacology 187 (3), 137-146, 2003
5412003
Proposed minimum reporting standards for data analysis in metabolomics
R Goodacre, D Broadhurst, AK Smilde, BS Kristal, JD Baker, R Beger, ...
Metabolomics 3, 231-241, 2007
5092007
High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues
O Beckonert, M Coen, HC Keun, Y Wang, TMD Ebbels, E Holmes, ...
Nature protocols 5 (6), 1019-1032, 2010
4182010
Integrated pathway-level analysis of transcriptomics and metabolomics data with IMPaLA
A Kamburov, R Cavill, TMD Ebbels, R Herwig, HC Keun
Bioinformatics 27 (20), 2917-2918, 2011
3982011
Recursive Segment-Wise Peak Alignment of Biological 1H NMR Spectra for Improved Metabolic Biomarker Recovery
KA Veselkov, JC Lindon, TMD Ebbels, D Crockford, VV Volynkin, ...
Analytical chemistry 81 (1), 56-66, 2009
3872009
The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements
JC Lindon, HC Keun, TMD Ebbels, JMT Pearce, E Holmes, JK Nicholson
Future Medicine Ltd 6 (7), 691-699, 2005
3452005
Analytical reproducibility in 1H NMR-based metabonomic urinalysis
HC Keun, TMD Ebbels, H Antti, ME Bollard, O Beckonert, G Schlotterbeck, ...
Chemical research in toxicology 15 (11), 1380-1386, 2002
3242002
Optimized preprocessing of ultra-performance liquid chromatography/mass spectrometry urinary metabolic profiles for improved information recovery
KA Veselkov, LK Vingara, P Masson, SL Robinette, E Want, JV Li, ...
Analytical chemistry 83 (15), 5864-5872, 2011
3062011
Improved analysis of multivariate data by variable stability scaling: application to NMR-based metabolic profiling
HC Keun, TMD Ebbels, H Antti, ME Bollard, O Beckonert, E Holmes, ...
Analytica chimica acta 490 (1-2), 265-276, 2003
2382003
Spectral editing and pattern recognition methods applied to high-resolution magic-angle spinning 1H nuclear magnetic resonance spectroscopy of liver tissues
Y Wang, ME Bollard, H Keun, H Antti, O Beckonert, TM Ebbels, JC Lindon, ...
Analytical biochemistry 323 (1), 26-32, 2003
2142003
Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach
TMD Ebbels, HC Keun, OP Beckonert, ME Bollard, JC Lindon, E Holmes, ...
Journal of proteome research 6 (11), 4407-4422, 2007
2132007
Optimization and evaluation of metabolite extraction protocols for untargeted metabolic profiling of liver samples by UPLC-MS
P Masson, AC Alves, TMD Ebbels, JK Nicholson, EJ Want
Analytical Chemistry 82 (18), 7779-7786, 2010
2072010
Correction of mass calibration gaps in liquid chromatography–mass spectrometry metabolomics data
HP Benton, EJ Want, TMD Ebbels
Bioinformatics 26 (19), 2488-2489, 2010
2052010
Bayesian deconvolution and quantification of metabolites in complex 1D NMR spectra using BATMAN
J Hao, M Liebeke, W Astle, M De Iorio, JG Bundy, T Ebbels
Nature protocols 9 (6), 1416-1427, 2014
1962014
Urinary metabolic signatures of human adiposity
P Elliott, JM Posma, Q Chan, I Garcia-Perez, A Wijeyesekera, M Bictash, ...
Science translational medicine 7 (285), 285ra62-285ra62, 2015
1892015
The evolution of partial least squares models and related chemometric approaches in metabonomics and metabolic phenotyping
JM Fonville, SE Richards, RH Barton, CL Boulange, TMD Ebbels, ...
Journal of Chemometrics 24 (11‐12), 636-649, 2010
1892010
NMR-based metabonomic toxicity classification: hierarchical cluster analysis and k-nearest-neighbour approaches
O Beckonert, ME Bollard, TMD Ebbels, HC Keun, H Antti, E Holmes, ...
Analytica Chimica Acta 490 (1-2), 3-15, 2003
1882003
Design and analysis of metabolomics studies in epidemiologic research: a primer on-omic technologies
I Tzoulaki, TMD Ebbels, A Valdes, P Elliott, JPA Ioannidis
American journal of epidemiology 180 (2), 129-139, 2014
1852014
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