| Evolution of the B3 DNA binding superfamily: new insights into REM family gene diversification EAC Romanel, CG Schrago, RM Couñago, CAM Russo, M Alves-Ferreira PloS one 4 (6), e5791, 2009 | 156 | 2009 |
| Imperfect coordination chemistry facilitates metal ion release in the Psa permease RM Couñago, MP Ween, SL Begg, M Bajaj, J Zuegg, ML O'mara, ... Nature chemical biology 10 (1), 35-41, 2014 | 152 | 2014 |
| Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae SL Begg, BA Eijkelkamp, Z Luo, RM Counago, JR Morey, MJ Maher, ... Nature communications 6 (1), 6418, 2015 | 125 | 2015 |
| In vivo molecular evolution reveals biophysical origins of organismal fitness R Couñago, S Chen, Y Shamoo Molecular cell 22 (4), 441-449, 2006 | 121 | 2006 |
| AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae CD Plumptre, BA Eijkelkamp, JR Morey, F Behr, RM Couñago, ... Molecular microbiology 91 (4), 834-851, 2014 | 106 | 2014 |
| WNT activates the AAK1 kinase to promote clathrin-mediated endocytosis of LRP6 and establish a negative feedback loop MJ Agajanian, MP Walker, AD Axtman, RR Ruela-de-Sousa, DS Serafin, ... Cell reports 26 (1), 79-93. e8, 2019 | 73 | 2019 |
| Crystal structure of rice importin-α and structural basis of its interaction with plant-specific nuclear localization signals CW Chang, RLM Couñago, SJ Williams, M Bodén, B Kobe The Plant Cell 24 (12), 5074-5088, 2012 | 72 | 2012 |
| Distinctive conformation of minor site‐specific nuclear localization signals bound to importin‐α CW Chang, RM Couñago, SJ Williams, M Bodén, B Kobe Traffic 14 (11), 1144-1154, 2013 | 57 | 2013 |
| An adaptive mutation in adenylate kinase that increases organismal fitness is linked to stability–activity trade-offs R Counago, CJ Wilson, MI Pena, P Wittung-Stafshede, Y Shamoo Protein Engineering, Design & Selection 21 (1), 19-27, 2008 | 48 | 2008 |
| Gene replacement of adenylate kinase in the gram-positive thermophile Geobacillus stearothermophilus disrupts adenine nucleotide homeostasis and reduces cell … R Couñago, Y Shamoo Extremophiles 9, 135-144, 2005 | 42 | 2005 |
| A Glutathione-Dependent Detoxification System Is Required for Formaldehyde Resistance and Optimal Survival of Neisseria meningitidis in Biofilms NH Chen, RM Counago, KY Djoko, MP Jennings, MA Apicella, B Kobe, ... Antioxidants & redox signaling 18 (7), 743-755, 2013 | 40 | 2013 |
| SGC-AAK1-1: a chemical probe targeting AAK1 and BMP2K C Wells, RM Counago, JC Limas, TL Almeida, JG Cook, DH Drewry, ... ACS medicinal chemistry letters 11 (3), 340-345, 2019 | 38 | 2019 |
| Prokaryotic substrate-binding proteins as targets for antimicrobial therapies R M Counago, C A McDevitt, M P Ween, B Kobe Current Drug Targets 13 (11), 1400-1410, 2012 | 38 | 2012 |
| Experimental evolution of adenylate kinase reveals contrasting strategies toward protein thermostability C Miller, M Davlieva, C Wilson, KI White, R Couñago, G Wu, JC Myers, ... Biophysical journal 99 (3), 887-896, 2010 | 34 | 2010 |
| Biochemical and structural characterization of alanine racemase from Bacillus anthracis (Ames) RM Couñago, M Davlieva, U Strych, RE Hill, KL Krause BMC structural biology 9, 1-15, 2009 | 34 | 2009 |
| Novel bacterial MerR-like regulators: Their role in the response to carbonyl and nitrosative stress AG McEwan, KY Djoko, NH Chen, RLM Couñago, SP Kidd, AJ Potter, ... Advances in microbial physiology 58, 1-22, 2011 | 33 | 2011 |
| Mitochondrial uncoupling protein-dependent signaling in plant bioenergetics and stress response P Barreto, RM Counago, P Arruda Mitochondrion 53, 109-120, 2020 | 30 | 2020 |
| Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations RM Couñago, CK Allerston, P Savitsky, H Azevedo, PH Godoi, CI Wells, ... Scientific reports 7 (1), 7501, 2017 | 30 | 2017 |
| Structures of Orf virus chemokine binding protein in complex with host chemokines reveal clues to broad binding specificity RM Couñago, KM Knapp, Y Nakatani, SB Fleming, M Corbett, LM Wise, ... Structure 23 (7), 1199-1213, 2015 | 29 | 2015 |
| In depth analysis of kinase cross screening data to identify CAMKK2 inhibitory scaffolds SN O’Byrne, JW Scott, JR Pilotte, AS Santiago, CG Langendorf, JS Oakhill, ... Molecules 25 (2), 325, 2020 | 28 | 2020 |
