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George Carlson
George Carlson
University of California, San Francisco; McLaughlin Research Institute
Geverifieerd e-mailadres voor ucsf.edu
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Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice
M Citron, D Westaway, W Xia, G Carlson, T Diehl, G Levesque, ...
Nature medicine 3 (1), 67, 1997
18481997
Propagation of tau pathology in a model of early Alzheimer's disease
A de Calignon, M Polydoro, M Suárez-Calvet, C William, DH Adamowicz, ...
Neuron 73 (4), 685-697, 2012
15082012
Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695
MA Chishti, DS Yang, C Janus, AL Phinney, P Horne, J Pearson, ...
Journal of Biological Chemistry 276 (24), 21562-21570, 2001
11912001
Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication
SB Prusiner, M Scott, D Foster, KM Pan, D Groth, C Mirenda, M Torchia, ...
Cell 63 (4), 673-686, 1990
11551990
Tau mislocalization to dendritic spines mediates synaptic dysfunction independently of neurodegeneration
BR Hoover, MN Reed, J Su, RD Penrod, LA Kotilinek, MK Grant, R Pitstick, ...
Neuron 68 (6), 1067-1081, 2010
11212010
Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques
M Scott, D Foster, C Mirenda, D Serban, F Coufal, M Wälchli, M Torchia, ...
Cell 59 (5), 847-857, 1989
9461989
The relationship between Aβ and memory in the Tg2576 mouse model of Alzheimer's disease
MA Westerman, D Cooper-Blacketer, A Mariash, L Kotilinek, ...
Journal of Neuroscience 22 (5), 1858-1867, 2002
9172002
Age-dependent neurofibrillary tangle formation, neuron loss, and memory impairment in a mouse model of human tauopathy (P301L)
M Ramsden, L Kotilinek, C Forster, J Paulson, E McGowan, K SantaCruz, ...
Journal of Neuroscience 25 (46), 10637-10647, 2005
7212005
Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel
RC Moore, IY Lee, GL Silverman, PM Harrison, R Strome, C Heinrich, ...
Journal of molecular biology 292 (4), 797-817, 1999
6921999
Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins
KK Hsiao, DR Borchelt, K Olson, R Johannsdottir, C Kitt, W Yunis, S Xu, ...
Neuron 15 (5), 1203-1218, 1995
6751995
Distinct prion proteins in short and long scrapie incubation period mice
D Westaway, PA Goodman, CA Mirenda, MP McKinley, GA Carlson, ...
Cell 51 (4), 651-662, 1987
6371987
Caspase activation precedes and leads to tangles
A de Calignon, LM Fox, R Pitstick, GA Carlson, BJ Bacskai, ...
Nature 464 (7292), 1201-1204, 2010
6362010
Linkage of prion protein and scrapie incubation time genes
GA Carlson, DT Kingsbury, PA Goodman, S Coleman, ST Marshall, ...
Cell 46 (4), 503-511, 1986
4911986
Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains
P Markel, P Shu, C Ebeling, GA Carlson, DL Nagle, JS Smutko, KJ Moore
Nature genetics 17 (3), 280, 1997
4901997
Identification and characterization of the mouse obesity gene tubby: a member of a novel gene family
PW Kleyn, W Fan, SG Kovats, JJ Lee, JC Pulido, Y Wu, LR Berkemeier, ...
Cell 85 (2), 281-290, 1996
4761996
SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein
C Iadecola, F Zhang, K Niwa, C Eckman, SK Turner, E Fischer, S Younkin, ...
Nature neuroscience 2 (2), 157-161, 1999
4731999
Region-specific dissociation of neuronal loss and neurofibrillary pathology in a mouse model of tauopathy
TL Spires, JD Orne, K SantaCruz, R Pitstick, GA Carlson, KH Ashe, ...
The American journal of pathology 168 (5), 1598-1607, 2006
4522006
Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins
D Westaway, SJ DeArmond, J Cayetano-Canlas, D Groth, D Foster, ...
Cell 76 (1), 117-129, 1994
4261994
Nox2-derived radicals contribute to neurovascular and behavioral dysfunction in mice overexpressing the amyloid precursor protein
L Park, P Zhou, R Pitstick, C Capone, J Anrather, EH Norris, L Younkin, ...
Proceedings of the National Academy of Sciences 105 (4), 1347-1352, 2008
3662008
Cerebrovascular autoregulation is profoundly impaired in mice overexpressing amyloid precursor protein
K Niwa, K Kazama, L Younkin, SG Younkin, GA Carlson, C Iadecola
American Journal of Physiology-Heart and Circulatory Physiology 283 (1 …, 2002
3512002
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Artikelen 1–20