| RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome L Duprez, N Takahashi, F Van Hauwermeiren, B Vandendriessche, ... Immunity 35 (6), 908-918, 2011 | 588 | 2011 |
| Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models N Takahashi, L Duprez, S Grootjans, A Cauwels, W Nerinckx, ... Cell death & disease 3 (11), e437-e437, 2012 | 482 | 2012 |
| Endothelial Outgrowth Cells Are Not Derived From CD133+ Cells or CD45+ Hematopoietic Precursors F Timmermans, F Van Hauwermeiren, M De Smedt, R Raedt, ... Arteriosclerosis, thrombosis, and vascular biology 27 (7), 1572-1579, 2007 | 470 | 2007 |
| Treatment of TNF mediated diseases by selective inhibition of soluble TNF or TNFR1 F Van Hauwermeiren, RE Vandenbroucke, C Libert Cytokine & growth factor reviews 22 (5-6), 311-319, 2011 | 183 | 2011 |
| Nlrp6-and ASC-dependent inflammasomes do not shape the commensal gut microbiota composition M Mamantopoulos, F Ronchi, F Van Hauwermeiren, S Vieira-Silva, ... Immunity 47 (2), 339-348. e4, 2017 | 174 | 2017 |
| Familial Mediterranean fever mutations lift the obligatory requirement for microtubules in Pyrin inflammasome activation H Van Gorp, PHV Saavedra, NM de Vasconcelos, N Van Opdenbosch, ... Proceedings of the National Academy of Sciences 113 (50), 14384-14389, 2016 | 162 | 2016 |
| Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF RE Vandenbroucke, E Dejonckheere, F Van Hauwermeiren, S Lodens, ... EMBO molecular medicine 5 (7), 1000-1016, 2013 | 142 | 2013 |
| Matrix metalloprotease 8-dependent extracellular matrix cleavage at the blood–CSF barrier contributes to lethality during systemic inflammatory diseases RE Vandenbroucke, E Dejonckheere, P Van Lint, D Demeestere, ... Journal of Neuroscience 32 (29), 9805-9816, 2012 | 130 | 2012 |
| Caspase-1 engagement and TLR-induced c-FLIP expression suppress ASC/caspase-8-dependent apoptosis by inflammasome sensors NLRP1b and NLRC4 N Van Opdenbosch, H Van Gorp, M Verdonckt, PHV Saavedra, ... Cell reports 21 (12), 3427-3444, 2017 | 116 | 2017 |
| MCC950/CRID3 potently targets the NACHT domain of wild-type NLRP3 but not disease-associated mutants for inflammasome inhibition L Vande Walle, IB Stowe, P Šácha, BL Lee, D Demon, A Fossoul, ... PLoS biology 17 (9), e3000354, 2019 | 107 | 2019 |
| Regulation and dysregulation of tumor necrosis factor receptor-1 L Puimège, C Libert, F Van Hauwermeiren Cytokine & growth factor reviews 25 (3), 285-300, 2014 | 99 | 2014 |
| Type I interferon drives tumor necrosis factor–induced lethal shock L Huys, F Van Hauwermeiren, L Dejager, E Dejonckheere, S Lienenklaus, ... Journal of Experimental Medicine 206 (9), 1873-1882, 2009 | 98 | 2009 |
| Neutralizing TNFα restores glucocorticoid sensitivity in a mouse model of neutrophilic airway inflammation L Dejager, K Dendoncker, M Eggermont, J Souffriau, ... Mucosal immunology 8 (6), 1212-1225, 2015 | 89 | 2015 |
| Pro-inflammatory effects of matrix metalloproteinase 7 in acute inflammation RE Vandenbroucke, I Vanlaere, F Van Hauwermeiren, ... Mucosal Immunology 7 (3), 579-588, 2014 | 89 | 2014 |
| Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium F Van Hauwermeiren, M Armaka, N Karagianni, K Kranidioti, ... The Journal of clinical investigation 123 (6), 2590-2603, 2013 | 87 | 2013 |
| Generation and characterization of small single domain antibodies inhibiting human tumor necrosis factor receptor 1 S Steeland, L Puimège, RE Vandenbroucke, F Van Hauwermeiren, ... Journal of Biological Chemistry 290 (7), 4022-4037, 2015 | 81 | 2015 |
| NOD‐like receptors interfacing the immune and reproductive systems H Van Gorp, A Kuchmiy, F Van Hauwermeiren, M Lamkanfi The FEBS journal 281 (20), 4568-4582, 2014 | 77 | 2014 |
| Tumor necrosis factor inhibits glucocorticoid receptor function in mice: a strong signal toward lethal shock T Van Bogaert, S Vandevyver, L Dejager, F Van Hauwermeiren, I Pinheiro, ... Journal of Biological Chemistry 286 (30), 26555-26567, 2011 | 71 | 2011 |
| LPS resistance of SPRET/Ei mice is mediated by Gilz, encoded by the Tsc22d3 gene on the X chromosome I Pinheiro, L Dejager, I Petta, S Vandevyver, L Puimege, T Mahieu, ... EMBO molecular medicine 5 (3), 456-470, 2013 | 61 | 2013 |
| TNFR1-induced lethal inflammation is mediated by goblet and Paneth cell dysfunction F Van Hauwermeiren, RE Vandenbroucke, L Grine, S Lodens, ... Mucosal immunology 8 (4), 828-840, 2015 | 54 | 2015 |
