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Tyler Starr
Tyler Starr
Department of Biochemistry, University of Utah
Verified email at biochem.utah.edu - Homepage
Title
Cited by
Cited by
Year
Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding
TN Starr, AJ Greaney, SK Hilton, D Ellis, KHD Crawford, AS Dingens, ...
Cell 182 (5), 1295-1310. e20, 2020
18242020
Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies
AJ Greaney, AN Loes, KHD Crawford, TN Starr, KD Malone, HY Chu, ...
Cell host & microbe, 2021
11662021
Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition
AJ Greaney, TN Starr, P Gilchuk, SJ Zost, E Binshtein, AN Loes, SK Hilton, ...
Cell host & microbe 29 (1), 44-57. e9, 2021
10362021
Prospective mapping of viral mutations that escape antibodies used to treat COVID-19
TN Starr, AJ Greaney, A Addetia, WW Hannon, MC Choudhary, ...
Science 371 (6531), 850-854, 2021
7312021
Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016
TN Starr, AJ Greaney, AS Dingens, JD Bloom
Cell Reports Medicine 2 (4), 100255, 2021
4622021
Epistasis in protein evolution
TN Starr, JW Thornton
Protein Science, 2016
4502016
SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape
TN Starr, N Czudnochowski, Z Liu, F Zatta, YJ Park, A Addetia, D Pinto, ...
Nature 597 (7874), 97-102, 2021
3882021
Mapping mutations to the SARS-CoV-2 RBD that escape binding by different classes of antibodies
AJ Greaney, TN Starr, CO Barnes, Y Weisblum, F Schmidt, M Caskey, ...
Nature Communications 12 (1), 1-14, 2021
376*2021
Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail
J Dong, SJ Zost, AJ Greaney, TN Starr, AS Dingens, EC Chen, RE Chen, ...
Nature Microbiology 6 (10), 1233-1244, 2021
357*2021
Broad sarbecovirus neutralization by a human monoclonal antibody
MA Tortorici, N Czudnochowski, TN Starr, R Marzi, AC Walls, F Zatta, ...
Nature 597 (7874), 103-108, 2021
2112021
Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection
AJ Greaney, AN Loes, LE Gentles, KHD Crawford, TN Starr, KD Malone, ...
Science translational medicine 13 (600), eabi9915, 2021
2072021
Alternative evolutionary histories in the sequence space of an ancient protein
TN Starr, LK Picton, JW Thornton
Nature 549 (7672), 409-413, 2017
1862017
Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution
TN Starr, AJ Greaney, WW Hannon, AN Loes, K Hauser, JR Dillen, E Ferri, ...
Science 377 (6604), 420-424, 2022
1452022
Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines
AC Walls, MC Miranda, A Schäfer, MN Pham, A Greaney, ...
Cell 184 (21), 5432-5447. e16, 2021
1392021
Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models
AA Cohen, N van Doremalen, AJ Greaney, H Andersen, A Sharma, ...
Science 377 (6606), eabq0839, 2022
1262022
ACE2 binding is an ancestral and evolvable trait of sarbecoviruses
TN Starr, SK Zepeda, AC Walls, AJ Greaney, S Alkhovsky, D Veesler, ...
Nature 603 (7903), 913-918, 2022
1162022
Systematic Mutant Analyses Elucidate General and Client-Specific Aspects of Hsp90 Function
P Mishra, JM Flynn, TN Starr, DNA Bolon
Cell Reports 15 (3), 588-598, 2016
1142016
Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry
YJ Park, A De Marco, TN Starr, Z Liu, D Pinto, AC Walls, F Zatta, ...
Science 375 (6579), 449-454, 2022
1042022
Pervasive contingency and entrenchment in a billion years of Hsp90 evolution
TN Starr, JM Flynn, P Mishra, DNA Bolon, JW Thornton
Proceedings of the National Academy of Sciences 115 (17), 4453-4458, 2018
1002018
Selection analysis identifies unusual clustered mutational changes in Omicron lineage BA. 1 that likely impact Spike function
DP Martin, S Lytras, AG Lucaci, W Maier, B Grüning, SD Shank, S Weaver, ...
Molecular Biology and Evolution, 2022
97*2022
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