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Alvin WT Ng
Alvin WT Ng
Presidential Postdoctoral Fellow at Lee Kong Chian School of Medicine, Singapore
Geverifieerd e-mailadres voor ntu.edu.sg
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The repertoire of mutational signatures in human cancer
LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AWT Ng, Y Wu, A Boot, ...
Nature 578 (7793), 94-101, 2020
25342020
Pan-cancer analysis of whole genomes.
S Hirano, L Yang, M Juul, CA Purdie, BP O'Neill, R Kabbe, ...
Nature 578 (DKFZ-2020-01051), 82-93, 2020
1670*2020
Whole-genome and epigenomic landscapes of etiologically distinct subtypes of cholangiocarcinoma
A Jusakul, I Cutcutache, CH Yong, JQ Lim, MN Huang, N Padmanabhan, ...
Cancer Discovery 7 (10), 1116-1135, 2017
7202017
Aristolochic acids and their derivatives are widely implicated in liver cancers in Taiwan and throughout Asia
AWT Ng, SL Poon, MN Huang, JQ Lim, A Boot, W Yu, Y Suzuki, ...
Science translational medicine 9 (412), eaan6446, 2017
3342017
In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumors
A Boot, MN Huang, AWT Ng, SC Ho, JQ Lim, Y Kawakami, K Chayama, ...
Genome research 28 (5), 654-665, 2018
1442018
Genome-scale mutational signatures of aflatoxin in cells, mice, and human tumors
MN Huang, W Yu, WW Teoh, M Ardin, A Jusakul, AWT Ng, A Boot, ...
Genome research 27 (9), 1475-1486, 2017
1112017
Global epidemiology and genetics of hepatocellular carcinoma
MR Toh, EYT Wong, SH Wong, AWT Ng, LH Loo, PKH Chow, J Ngeow
Gastroenterology 164 (5), 766-782, 2023
872023
Experimental and pan-cancer genome analyses reveal widespread contribution of acrylamide exposure to carcinogenesis in humans
M Zhivagui, AWT Ng, M Ardin, MI Churchwell, M Pandey, C Renard, ...
Genome research 29 (4), 521-531, 2019
752019
Epigenomic Promoter Alterations Amplify Gene Isoform and Immunogenic Diversity in Gastric Adenocarcinoma
A Qamra, M Xing, N Padmanabhan, JJT Kwok, S Zhang, C Xu, YS Leong, ...
Cancer Discovery 7 (6), 630-651, 2017
502017
Characterization of colibactin-associated mutational signature in an Asian oral squamous cell carcinoma and in other mucosal tumor types
A Boot, AWT Ng, FT Chong, SC Ho, W Yu, DSW Tan, NG Iyer, SG Rozen
Genome research 30 (6), 803-813, 2020
452020
Extrachromosomal DNA in the cancerous transformation of Barrett’s oesophagus
J Luebeck, AWT Ng, PC Galipeau, X Li, CA Sanchez, ...
Nature, 1-8, 2023
302023
The Drosophila Dicer-1 Partner Loquacious Enhances miRNA Processing from Hairpins with Unstable Structures at the Dicing Site
MYT Lim, AWT Ng, Y Chou, TP Lim, A Simcox, G Tucker-Kellogg, ...
Cell reports 15 (8), 1795-1808, 2016
232016
Functional genomics identifies specific vulnerabilities in PTEN-deficient breast cancer
YC Tang, SC Ho, E Tan, AWT Ng, JR McPherson, GYL Goh, BT Teh, ...
Breast Cancer Research 20 (1), 22, 2018
202018
Serial circulating tumor DNA detection using a personalized, tumor-informed assay in esophageal adenocarcinoma patients following resection
E Ococks, S Sharma, AWT Ng, A Aleshin, RC Fitzgerald, E Smyth
Gastroenterology 161 (5), 1705-1708. e2, 2021
112021
Rearrangement processes and structural variations show evidence of selection in oesophageal adenocarcinomas
AWT Ng, G Contino, S Killcoyne, G Devonshire, R Hsu, S Abbas, J Su, ...
Communications Biology 5 (1), 1-12, 2022
82022
Accuracy of mutational signature software on correlated signatures
Y Wu, EHZ Chua, AWT Ng, A Boot, SG Rozen
Scientific reports 12 (1), 1-12, 2022
62022
DNA epigenetic signature predictive of benefit from neoadjuvant chemotherapy in oesophageal adenocarcinoma: results from the MRC OE02 trial
R Sundar, A Ng, H Zouridis, N Padmanabhan, T Sheng, S Zhang, MH Lee, ...
European Journal of Cancer 123, 48-57, 2019
52019
Understanding the malignant potential of gastric metaplasia of the oesophagus and its relevance to Barrett’s oesophagus surveillance: individual-level data analysis
EL Black, E Ococks, G Devonshire, AWT Ng, M O’Donovan, S Malhotra, ...
Gut, 2023
32023
Mutational processes in cancer preferentially affect binding of particular transcription factors
M Liu, A Boot, AWT Ng, R Gordân, SG Rozen
Scientific reports 11 (1), 1-12, 2021
32021
DNA methylation signature predictive of benefit from neoadjuvant chemotherapy in esophageal adenocarcinoma: Results from the MRC OEO2 phase III trial.
R Sundar, A Ng, H Zouridis, T Sheng, S Zhang, MH Lee, N Padmanabhan, ...
Journal of Clinical Oncology 37 (4_suppl), 43-43, 2019
22019
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Artikelen 1–20